Systems and methods for cleaning and maintaining artificial airways sized for insertion within pediatric or neonatal patients (e.g., external diameters of less than 5 mm) are disclosed. The system includes a multi-port ventilator manifold configured to couple to a ventilation source, thereby forming a ventilator circuit with the patient. The manifold includes an occluder configured to advantageously reduce an amount of dead space in the manifold so as to prevent less of positive end expiratory pressure of the ventilator circuit and reduce the likelihood of broncho-pulmonary dysplasia of the patient, or even premature death.

Systems and methods for treating biologic fluids are disclosed. Some disclosed embodiments may be used to filter cerebrospinal fluid (CSF) from a human or animal subject, heat CSF to a target temperature, cool CSF to a target temperature, apply light treatment to CSF, separate cells via their dielectric properties, apply spiral and/or centrifugal separation, introduce additives to target particles, and/or apply combinations thereof. The method may include the steps of withdrawing fluid comprising CSF, treating the fluid, and returning a portion of the treated fluid to the subject. During operation of the system, various parameters may be modified, such as flow rate.

A ventilator that moves breathable air into and out of the lungs of a patient. The ventilator includes an inspiratory circuit with an inlet, a bellows, and an outlet port for moving air into the lungs of the patient. An expiratory circuit includes an inlet port and a discharge port for moving the air out of the lungs. The inspiratory circuit is adjustable to control a number of breathes per time period and a volume of the breaths.

A hood for a sterilization system including a return line (132) to provide for airflow between first and second ends; a hood (116) having an opening situated in a top wall and configured to be coupled to a tube; and couplers (126) configured to couple the hood to adjacent ones of a plurality of support struts (114) to configure the hood to form an opening (128) leading to a cavity (129), wherein the cavity is configured to receive at least a portion of a head of a subject (101) receiving respiratory gas from a ventilator (170) such that the plurality of support struts are situated outside of the cavity, wherein the hood is configured to enable ambient air into the airflow while over the portion of the head of the subject.

Systems and methods for cleaning and maintaining artificial airways sized for insertion within pediatric or neonatal patients (e.g., external diameters of less than 5 mm) are disclosed. The system includes a multi-port ventilator manifold configured to couple to a ventilation source, thereby forming a ventilator circuit with the patient. The manifold includes an occluder configured to advantageously reduce an amount of dead space in the manifold so as to prevent loss of positive end expiratory pressure of the ventilator circuit and reduce the likelihood of broncho-pulmonary dysplasia of the patient, or even premature death.

A method of reducing the risk of ventilator-associated pneumonia by decontaminating the oropharynx using a safe, antimicrobial light-emitting device.

A treadmill may include two separate left and right belts rotating around two sets of rollers, four legs having an adjustable height via air suspension to customize an inclination of the treadmill, a thermoelectric assembly, a fragrance assembly having a rotating fragrance cartridge to emit various smells toward a user of the treadmill, a display on which exercise programs are played, and an attachment module having a dispensing tray on which treats are dispensed. A handle of the treadmill may have a sensor to sense a height and front-rear position, and a belt divider provided between the left and right belts may have position or proximity sensors to sense a left-right position. An inclination of the treadmill may be automatically adjusted according to positions detected by the sensors, and the fragrance assembly, attachment module, and inclination may be automatically operated in accordance with an exercise program played on the display.

Liquid drug cartridges and an associated inhaler are used to deliver one more separate doses of an aerosolized liquid drug. A cartridge includes a container for storing the liquid drug, an end cap having an ejection opening, a filter element, and a piston that is repositionable relative to the container to selectively eject a volume of liquid drug from the ejection opening. The filter element filters the liquid drug prior to ejection from the ejection opening. The liquid drug cartridge can be coupled with an inhaler that includes an aerosol generator. The aerosol generator includes a vibratable membrane onto which the liquid drug is ejected. The liquid drug is aerosolized by the vibration of the membrane for inhalation by a user.

The present invention provides systems, methods, and articles for stress reduction and sleep promotion. A stress reduction and sleep promotion system includes at least one remote device, at least one body sensor, and at least one remote server. In other embodiments, the stress reduction and sleep promotion system includes machine learning.

Described is a method and device for dilating a tubular anatomical structure. The device and method can be useful for extracting a blood clot in an artery of a mammal by concentrically irradiating an inner wall of the occluded artery using an ultraviolet (UV) laser beam delivered by an optical fiber having an external or inverted conical tip. Dilation results from photophysical production and release of nitric oxide from the cells lining the arterial wall when UV laser light is projected as a ring beam onto the inner arterial wall. This “minimal contact persistent dilation system” prepares the artery for safer mechanical extraction by thrombectomy, owing to decrease in friction and dissolution of chemical bonding.