A smoking substitute apparatus comprising an air inlet, a first passage leading from the air inlet to a first outlet, and an aerosol generator arranged in fluid communication with the first passage, the aerosol generator being operable to generate an aerosol from an aerosol precursor, to flow in use along the first passage downstream of the aerosol generator for inhalation by a user drawing on the outlet. The smoking substitute apparatus further comprises a second passage leading from the air inlet to a second outlet, separate from the first outlet, wherein the second passage bypasses the first passage downstream of the aerosol generator.

An aerosol unit for an aerosol dispenser, which aerosol unit comprises an axially oriented body, having a distal inlet part and a proximal outlet part; a carrier member arranged in the body, transversally to the axis between the inlet part and the outlet part; and wherein the carrier member comprises through-holes which place the inlet part in fluid communication with the outlet part, and wherein the carrier member is insert-moulded into the body such that a contact surface between the carrier and the body forms an air-tight seal.

A blood processing apparatus may include a heat exchanger and a gas exchanger. At least one of the heat exchanger and the gas exchanger may be configured to impart a radial component to blow flow through the heat exchanger and/or gas exchanger. The heat exchanger may be configured to cause blood flow to follow a spiral flow path.

A blood processing apparatus may include a heat exchanger and a gas exchanger. At least one of the heat exchanger and the gas exchanger may be configured to impart a radial component to blow flow through the heat exchanger and/or gas exchanger. The heat exchanger may be configured to cause blood flow to follow a spiral flow path.

A nasal cannula interface is provided for a respiratory support system configured to receive a breathable gases flow, the nasal cannula interface comprising: a. an inlet to receive the gases flow; b. at least one nasal prong configured to receive the gases flow from the inlet, and to be received in, and to deliver the gases flow to, a nare of the patient. The nasal cannula interface may comprise one or more structural features that are configured to help manage, avoid and/or reduce generation of aerosols by the patient during breathing and/or whilst breathing gases from a respiratory support apparatus.

The present disclosure pertains to a system and method for facilitating pressure support therapy, mechanical inexsufflation therapy, and suctioning therapy for a subject. The system and method described herein offer a novel combination of mechanical inexsufflation with suctioning from a vacuum system. The invasive nature of current closed suctioning systems poses many potential risks, such as tissue trauma, less optimum secretion clearance at the peripheral airway, and lung decruitment. The system and method described herein provide a non-invasive method of suctioning with a suctioning volume measurement and a monitoring alarm to ensure a baseline lung volume and a positive end expiratory pressure (PEEP) level are maintained. This non-invasive method of suctioning is provided together with mechanical inexsufflation and pressure support therapy.

A cushion module for a patient interface is disclosed. The cushion module comprising a first cavity, a second cavity, a nasal aperture and an oral aperture. The first and second cavities are separated by a cavity wall that enables respiratory gas to flow within the cushion module between the first and second cavities when in use. Additionally, the first cavity is configured to communicate respiratory gas to both the mouth and the nares of a patient via the oral aperture and the nasal aperture respectively. The cushion module comprises an exhaust vent to communicate respiratory gas from within the cushion module to externally of the cushion module and the second cavity is in communication with the exhaust vent. Also disclosed are a cavity wall and a cushion module.

An inhaler device for pulmonary delivery of at least one substance from a drug dose cartridge to an inhaling user, including: a first conduit for conducting a carrier airflow to a proximal opening of a mouthpiece for use by the user; a holder configured to position the dose cartridge within the carrier airflow; and a second conduit for conducting a shunting airflow to the mouthpiece without passing through the dose cartridge position. In some embodiments, a controller connected to a valve controls a rate of carrier airflow, for example by controlling the shunting airflow, based on a sensor indication of airflow rate and a target airflow profile.

A blood oxygenator has a housing with a first end opposite a second end and a sidewall extending between the first end and the second end along a longitudinal axis. The housing may define an interior chamber having a fluid inlet and a fluid outlet. The blood oxygenator further has a gas exchange medium positioned within the interior chamber. The gas exchange medium may have a plurality of hollow fibers rolled into a spiral shape. The blood oxygenator further has a flow diverter positioned within the interior chamber and configured for guiding fluid flow through the gas exchange medium.

An inhaler device for pulmonary delivery of at least one substance from a drug dose cartridge to an inhaling user, including: a first conduit for conducting a carrier airflow to a proximal opening of a mouthpiece for use by the user; a holder configured to position the dose cartridge within the carrier airflow; and a second conduit for conducting a shunting airflow to the mouthpiece without passing through the dose cartridge position. In some embodiments, a controller connected to a valve controls a rate of carrier airflow, for example by controlling the shunting airflow, based on a sensor indication of airflow rate and a target airflow profile.