Containment units, dry powder inhalers, delivery systems, and methods for the same are disclosed. Exemplary devices are configured to have inlets and outlets which are formed with the containment walls of a containment unit. Air jets formed by the configuration of inlet(s) and outlet(s) inside the containment unit create significant turbulence and deaggregate the powder. Delivery system components downstream of the containment unit may integrate the exiting aerosol plume with a low flow nasal cannula air stream for delivery to a subject.

The present invention comprises a compact atomizer that substantially encapsulates a standard inhalant canister and allows for in-line dispensing through a mouthpiece formed in an actuating cover. The compact atomizer comprises an actuating cover and housing that cooperate to secure the canister. By compressing the actuating cover and housing together, a nozzle of the canister is depressed to release a portion of substance within the canister. Compression is enabled by an actuation surface formed in the actuating cover. Substance is released in-line with the canister through a mouthpiece at the end of the actuating cover. The result is a small, compact, yet attractive atomizer that can be carried in a pocket or the like while keeping the canister free of debris.

A dry powder inhaler is disclosed. The dry powder inhaler includes a first housing member and a second housing member being rotatable in relation to one another to prepare administering a medicament dose from at least one medicament reservoir. An air inlet, a first air outlet, and a second air outlet are provided. The air inlet and the first air outlet are connected by a first air channel via a dosage mechanism configured to arrange a dose from the reservoir into the first air channel. The air inlet and the second air outlet are connected by a second air channel. An inhalation chimney is provided internally forming the proximal portion of the first air channel and comprising the first air outlet at a first end thereof.

An aerosol generator for an aerosol dispenser is presented where, the aerosol generator has a housing having an inlet part comprising a liquid inlet configured to guide a liquid jet (L) into the housing and an air inlet configured to guide an air flow into the housing. The housing further having an outlet part having an aerosol outlet configured to guide an aerosol (C) of liquid mixed with air out of the housing. The air inlet is configured such that at least part of the air flow entering the housing through the air inlet is obstructed at a distance from the liquid jet (L) entering the housing through the liquid inlet, thereby creating a source of turbulence in the housing to interact with droplets of the liquid jet (L) to prevent coalescence of the droplets.

A spray device includes a mouthpiece that accommodates a spray nozzle unit. The spray nozzle unit is operatively connected to a liquid reservoir to receive a pressurized liquid to be sprayed. A connection between the spray nozzle unit and the liquid reservoir is effected by a flexible tube that connects at one end substantially fixedly to the mouth piece in fluid communication with the spray nozzle device. The liquid reservoir is interchangeably coupled to the opposite end of the flexible tube and, preferably, comprises a standard syringe. A spray delivery device comprises a holder for holding the syringe and has at least one manipulator member that is configured to impose an enhanced force on the plunger.

Core annular flow is used to enable the subcutaneous delivery of a viscous fluid such as a protein therapeutic formulation. The high-viscosity fluid is surrounded by a low-viscosity fluid, and the low-viscosity fluid lubricates the passage of the high-viscosity fluid. This allows the use of protein formulations that have a higher concentration and a higher viscosity at comparatively reduced injection forces and reduced injection times. Several different embodiments of injection devices that provide core annular flow are described herein.

The present invention relates to a filtering syringe, and more particularly, to an apparatus obtained by improving a syringe provided with a filter means for filtering foreign substances such as glass fragments of an ampoule, so as to prevent an injection needle or an injection flow passage from being contaminated with the foreign substances while allowing a liquid medicine to be smoothly sucked with a smaller force. The filtering syringe is configured such that the injection needle or the injection flow passage is isolated from the suction flow passage which is upstream of the filter means and in which the foreign substances may remain together with the liquid medicine, thereby allowing the liquid medicine to be sucked with a force less than that required for a conventional syringe and thus maximizing user's convenience and marketability of the syringe.

Core annular flow is used to enable the subcutaneous delivery of a viscous fluid such as a protein therapeutic formulation. The high-viscosity fluid is surrounded by a low-viscosity fluid, and the low-viscosity fluid lubricates the passage of the high-viscosity fluid. This allows the use of protein formulations that have a higher concentration and a higher viscosity at comparatively reduced injection forces and reduced injection times. Several different embodiments of injection devices that provide core annular flow are described herein.

Core annular flow is used to enable the subcutaneous delivery of a viscous fluid such as a protein therapeutic formulation. The high-viscosity fluid is surrounded by a low-viscosity fluid, and the low-viscosity fluid lubricates the passage of the high-viscosity fluid. This allows the use of protein formulations that have a higher concentration and a higher viscosity at comparatively reduced injection forces and reduced injection times. Several different embodiments of injection devices that provide core annular flow are described herein.

Aspects of the disclosure describe a design that isolates concentrated oxygen from electrical and/or flammable components of a ventilator. In an example, ventilator components containing or otherwise interacting with concentrated oxygen are isolated from the electrical equipment and/or drained to an exterior of the housing of the ventilator, in case of a leak. For example, an isolating structure encases the concentrated oxygen-carrying components to prevent concentrated oxygen from inadvertently leaking into the inside of the housing of the ventilator. The isolating structure may be a sleeve. An isolation gas inside the isolating structure may be fluidly coupled with ambient air outside the housing of the ventilator to allow the escape of isolation gas outside of the ventilator housing.