An implantable glymphatic pump configured to flush metabolites from a brain parenchyma of a patient. The implantable glymphatic pump including at least one spinal catheter having a distal end configured to be positioned within an intrathecal space of a spine of a patient, at least one cranial catheter having a distal end configured to be positioned within a brain parenchyma of the patient, and an implantable pump configured to draw cerebrospinal fluid from the intrathecal space of the spine in the patient via the at least one spinal catheter, and reintroduce said cerebrospinal fluid to the brain parenchyma of the patient via the one or more cranial catheters to encourage a flow of the cerebrospinal fluid through the brain parenchyma.

Described herein are noninvasive electrical stimulation devices, systems and methods for stimulation of the Vagus nerve through its auricular branch to provide beneficial physiological responses in subjects, including alleviation, mitigation or elimination of symptoms of various disorders, including metabolic and inflammatory disorders.

Described herein are noninvasive electrical stimulation devices, systems and methods for stimulation of the Vagus nerve through its auricular branch to provide beneficial physiological responses in subjects, including alleviation, mitigation or elimination of symptoms of various disorders, including metabolic and inflammatory disorders.

A sleep-aiding audio signal updating method and apparatus in the artificial intelligence (AI) field is provided. The method includes: obtaining a first biological signal collected when a first audio signal in a sleep-aiding audio library is played, where the first biological signal is a biological signal of a first user; determining a sleep quality of the first user based on the first biological signal; and updating the sleep-aiding audio library based on the sleep quality of the first user, so that a sleep-aiding audio signal can be updated, to provide a proper sleep-aiding audio signal for a user, and ensure a sleep-aiding effect.

A sleep-aiding audio signal updating method and apparatus in the artificial intelligence (AI) field is provided. The method includes: obtaining a first biological signal collected when a first audio signal in a sleep-aiding audio library is played, where the first biological signal is a biological signal of a first user; determining a sleep quality of the first user based on the first biological signal; and updating the sleep-aiding audio library based on the sleep quality of the first user, so that a sleep-aiding audio signal can be updated, to provide a proper sleep-aiding audio signal for a user, and ensure a sleep-aiding effect.

An automated EP analysis apparatus for monitoring, detecting and identifying changes (adverse or recovering) to a physiological system generating the analyzed EPs, wherein the apparatus is adapted to characterize and classify EPs and create alerts of changes (adverse or recovering) to the physiological systems generating the EPs if the acquired EP waveforms change significantly in latency, amplitude or morphology.

An automated EP analysis apparatus for monitoring, detecting and identifying changes (adverse or recovering) to a physiological system generating the analyzed EPs, wherein the apparatus is adapted to characterize and classify EPs and create alerts of changes (adverse or recovering) to the physiological systems generating the EPs if the acquired EP waveforms change significantly in latency, amplitude or morphology.

A human body support has a plurality of electrodes arranged in an array and spaced longitudinally with respect to the human body. The array extends from an inferior position to a more superior position along the body. A sensor measures a parameter of the human body that is capable of indicating the presence of drowsiness. A controller has an input connected to the sensor for receiving a signal representing the sensed parameter and has outputs connected to each of the electrodes. The controller detects whether the sensed parameter is within a range indicating the presence of drowsiness and applies a wave of electrical stimuli against the human body in response to detection of a sensed parameter within the range. The electrical stimuli cause periodic tightening and relaxing of proximate muscles as the wave progresses in a direction from an inferior location on the human body toward a more superior location.

A human body support has a plurality of electrodes arranged in an array and spaced longitudinally with respect to the human body. The array extends from an inferior position to a more superior position along the body. A sensor measures a parameter of the human body that is capable of indicating the presence of drowsiness. A controller has an input connected to the sensor for receiving a signal representing the sensed parameter and has outputs connected to each of the electrodes. The controller detects whether the sensed parameter is within a range indicating the presence of drowsiness and applies a wave of electrical stimuli against the human body in response to detection of a sensed parameter within the range. The electrical stimuli cause periodic tightening and relaxing of proximate muscles as the wave progresses in a direction from an inferior location on the human body toward a more superior location.

An implantable glymphatic pump configured to flush metabolites from a brain parenchyma of a patient. The implantable glymphatic pump including at least one spinal catheter having a distal end configured to be positioned within an intrathecal space of a spine of a patient, at least one cranial catheter having a distal end configured to be positioned within a brain parenchyma of the patient, and an implantable pump configured to draw cerebrospinal fluid from the intrathecal space of the spine in the patient via the at least one spinal catheter, and reintroduce said cerebrospinal fluid to the brain parenchyma of the patient via the one or more cranial catheters to encourage a flow of the cerebrospinal fluid through the brain parenchyma.