An instrument having a dosing unit connected to a handle or housing of instrument. The dosing unit may include a reusable actuator with a drive unit and a single-use cartridge. The Cartridge may have a cylinder and a piston, and may be filled by a user prior to the intervention or may be prefilled by the manufacturer. The dosing unit is brought into an open position offset from housing by, for example, operating a latch slider and pulling the dosing unit in a proximal direction. After insertion of the cartridge, the dosing unit may be moved toward housing and the latched slider will lock the dosing unit into a closed position.

The present invention relates to a needle-free injector using pulsed shock waves, the needle-free injector comprising: a power unit generating pulsed power; a pulsed shock wave generating unit which receives the pulsed power and generates pulsed shock waves; an upper housing in which a liquid and the pulsed shock wave generating unit are disposed; a lower housing which is connected to the upper housing, and in which a drug is disposed; a shock wave transmission unit which is provided between the upper housing and the lower housing to separate the upper housing and the lower housing; and an injection unit which is disposed in the lower housing and inject the drug.

A transdermal injection component, comprising: an injection volume configured to contain an injectable treatment therein, a plunger, the injection volume being in fluid communication with at least one orifice such that the plunger is configured to exert the injectable treatment from the injection volume through the at least one orifice; the plunger sealably engaged with the injection volume, the plunger configured to exert the injectable treatment from the injection volume through the at least one orifice so as to effect transdermal injection of the injectable treatment to a patient; the transdermal injection component being configured to engage with an actuator device configured to effect movement of the plunger to exert the injectable treatment through the at least one orifice.

An apparatus may include a plunger and a substantially cylindrical body. The substantially cylindrical body may include an end portion having rounded edges and may define a cavity sized to receive the plunger. The substantially cylindrical body may include at least one opening extending from the cavity to an external surface. The at least one opening may a substantially irregular shape. In some embodiments, the at least one opening may extend from the cavity through a nub to the external surface. The nub may have a rounded shape. In some embodiments, the substantially irregular shape may include one of a slit, an oval shape, an elliptical shape, an hourglass shape, a rectangular shape, and a diamond shape. In some embodiments, the opening may be part of a non-cylindrical fluid passage.

The present invention relates to a device for injecting a material, the device comprising the laser generation unit generates laser beams at a repetition rate of 15 to 25 Hz such that an inject material is injected so as to penetrate into skin through the surface of skin. As described above, a device for delivering a material by applying an optimum inject cycle according to the present invention is advantageous in that a material can be injected at an optimum inject cycle and made to penetrate into skin without a needle, thereby improving the penetration efficiency and minimizing the residual material which has failed to penetrate.

A device for administering a fluid can include a cylinder, a piston connected to a piston rod, and a tensioning device connected to the piston rod. The tensioning device includes a ramp which is rotatable via a motor, a ramp track, and a roller which is in contact with the ramp track and which is mounted rotatably in a driver. The driver can be connected to the piston rod via a joint. In a tensioning procedure, the ramp track is rotated such that the roller runs on the region of inclination as far as the second plateau and the piston is thereby moved to its rear end position. In a dispensing procedure, the ramp track is rotated until the roller runs over a transfer region and, on account of the tensioning, is accelerated toward the first plateau and, as a result, the piston is moved toward the an dispensing end.

The present disclosure relates to a medicament delivery device comprising a medicament receiving element, at least one fluid chamber having a fluid outlet configured to direct fluid vapour towards the medicament receiving element, a heating element for heating the fluid in the at least one fluid chamber. The device is configured such that, in use, the heating element heats the fluid in the at least one fluid chamber to at least partially evaporate the fluid so that the vapor pressure in the at least one fluid chamber increases until the fluid is expelled out of the at least one fluid chamber through the fluid outlet towards the medicament receiving element and entrains the medicament towards the patient's skin.

A material for an injection nozzle is molded into a form that includes a sacrificial tip around the nozzle exit orifice. The sacrificial tip is then machined away using any suitable machining process to expose the exit orifice. In this manner, an injection nozzle can be fabricated with favorable geometric characteristics.

The devices, assemblies, and methods described herein utilize photoacoustic principals to create a jet of fluid using a ultrasonic resonance member and a pulsed laser light beam. The ultrasonic resonance member is a treated substrate having an liquid interface surface in contact with a fluid. When a pulsed laser light beam is applied to the treated substrate, pressure is generated via induced ultrasonic waves to urge the fluid into a jet stream.

An apparatus for injectate delivery includes a cartridge, a linear actuator, a rotary motor mechanically coupled the actuator, and a controller coupled to the motor. The controller controls a linear motion of the actuator by controlling an electrical input supplied to the motor in a first interval during which the motor is stationary with the linear actuator engaged with the cartridge to displace an injectate in the cartridge, a second interval following the first interval during which the controller accelerates the motor from stationary to a first speed selected to create a jet of the injectate from the cartridge with a velocity sufficient to pierce human tissue to a subcutaneous depth, a third interval during which the controller maintains the motor at or above the first speed, and a fourth interval during which the controller decelerates the motor to a second speed to deliver the injectate at the subcutaneous depth.