An autoinjector including a housing; an axially fixed product container; a torsion spring; a drive element; a propulsion element; and a needle protection sleeve is configured such that when the autoinjector is pressed against an injection location, the needle protection sleeve undergoes an actuation movement in the proximal direction. For discharging liquid from the product container through an injection needle into the injection location, the torsion spring sets the drive element into rotation and the rotating drive element causes a movement of the propulsion element and a piston in the product container in the distal direction. The autoinjector includes a coupling which, due to the actuation movement of the needle protection sleeve, releases the drive element for rotation, where the coupling is between a first and second coupling element in an engagement of locking surfaces, and can be disengaged by an axial coupling stroke of the two coupling elements.

An electronic add-on module for an injection device includes a longitudinal axis and a discharge button arranged at a proximal end and configured to be movable in a distal direction along the longitudinal axis for discharging a liquid medication out of a container of the injection device. The add-on module includes a sensor unit, a receiving region adapted to the shape of the housing of the injection device for placing on along the longitudinal axis thereof, and a holding mechanism configured to releasably secure the add-on module against moving axially relative to the injection device. The receiving region is configured such that the discharge button can be accessed or contacted when the add-on module is on the injection device. The add-on module comprises a release element configured to be moved solely on a plane perpendicular to the longitudinal axis in a release movement for releasing the holding mechanism.

A drive mechanism suitable for use in drug delivery devices is disclosed. The drive mechanism may be used with injector-type drug delivery devices, such as those permitting a user to set the delivery dose. The drive mechanism may include a housing, a dose dial sleeve, and a drive sleeve. A clutch is configured to permit rotation of the drive sleeve and the dose dial sleeve with respect to the housing when the dose dial sleeve and drive sleeve are coupled through the clutch. Conversely, when the dose dial sleeve and drive sleeve are in a de-coupled state, rotation of the dose dial sleeve with respect to the housing is permitted and rotation of the drive sleeve with respect to the housing is prevented. In the de-coupled state, axial movement of the drive sleeve transfers force in a longitudinal direction for actuation of a drug delivery device.

A crawling mechanism for a drug delivery device has a central longitudinal axis and is arranged to crawl in an axial direction. The crawling mechanism includes a housing and one or more swing members pivotally coupled to the housing that are arranged to swing relative to the housing between an initial position and a terminal position suitable for urging crawling of the mechanism.

Drug delivery systems and methods of use thereof for recording administration of a drug dose to a subject are provided. Aspects of the invention include a syringe stopper rod comprising a sensor component that is configured to detect a delivery signature, and to transmit a report comprising a drug dose completion signal to a data management component, e.g., a mobile computing device.

An apparatus (100) for use with an auto-injector configured to receive a syringe and comprising: a firing assembly (102) comprising a rearward portion (108), a plunger rod (110) moveable forward relative to the rearward portion (108) and a plunger rod driver (112) configured to drive the plunger rod (110) forward relative to the rearward portion (108); an insertion driver (106) configured to drive the syringe forwards on an insertion stroke for inserting a needle of the syringe into an injection site; and wherein the firing assembly (102) further comprises a retainer (114) engaged with the plunger rod (110) and/or the rearward portion (108) and configured to prevent forward movement of the plunger rod (110) relative to the rearward portion (108), and to disengage from the firing assembly (102) at a point on the insertion stroke.

A drug delivery device comprises a medication container containing medication for delivery and a detachable unit having an electronic circuit with a microprocessor. The electronic circuit is open and non-operational when the detachable component is assembled on the drug delivery device; and the electronic circuit is closed and operational when the detachable component is detached from the drug delivery device. The detachment of the detachable unit is an essential step to operate the drug delivery device. The detachable unit can be an activation protection cap or a needle shield remover for an autoinjector device. Alternatively, the detachable unit can be a needle shield remover for a pre-filled syringe.

Implementations of the present disclosure are directed to a medical handheld device that includes an actuating feature configured to generate a trigger signal, a sensor configured to detect a functionality of the medical handheld device in response to the trigger signal, and a haptic source configured to generate a haptic signal including information associated with the functionality of the medical handheld device.

A drug delivery device configured to provide a dose of a first medicament followed by a dose of a second medicament is disclosed. The device includes a main exterior body and an interior body. The device further includes a dual-chamber reservoir with (i) a first chamber holding the first medicament and (ii) a second chamber holding the second medicament. The device also includes a needle and a plunger. After activation of the device, the plunger is configured to (i) move the dual-chamber reservoir a given distance in a distal direction with respect to the interior body so that a distal end of the needle extends out of the interior body and (ii) after moving the dual-chamber reservoir the given distance, move in the distal direction with respect to the dual-chamber reservoir so as to eject from the needle the first medicament followed by the second medicament.

Automatic injection devices (i.e., auto-injectors) and methods are disclosed that use gas-generating chemical reactions for parenteral delivery of therapeutic fluids. The generated gas may place the auto-injector in a punctured configuration to puncture a patient's skin with a needle, an injected configuration to deliver the therapeutic fluid through the needle and into the puncture site, and/or a retracted configuration to withdraw the needle from the puncture site.