An autoinjector including a housing; an axially fixed product container; a torsion spring; a drive element; a propulsion element; and a needle protection sleeve is configured such that when the autoinjector is pressed against an injection location, the needle protection sleeve undergoes an actuation movement in the proximal direction. For discharging liquid from the product container through an injection needle into the injection location, the torsion spring sets the drive element into rotation and the rotating drive element causes a movement of the propulsion element and a piston in the product container in the distal direction. The autoinjector includes a coupling which, due to the actuation movement of the needle protection sleeve, releases the drive element for rotation, where the coupling is between a first and second coupling element in an engagement of locking surfaces, and can be disengaged by an axial coupling stroke of the two coupling elements.

A drug delivery device (100, 200) for delivering a fixed dose, comprising a drive mecha-nism comprising a drive spring (108, 208), and an activation mechanism comprising a connector (170, 270) adapted for activating the drive mechanism, wherein the drug de-livery device further comprises a split-dose-prevention mechanism adapted for limiting the axial movement of the connector during dosing. The split dose prevention mechanism comprises: (i) a split-dose-prevention structure (184, 284.1, 284.2) provided on the drive tube (180, 280) and extending in a circumferential direction, and (ii) a retention portion (178.3, 278.2) provided on the connector. For the drive tube being arranged in the intermediate position, the split-dose-prevention structure (184, 284.1, 284.2) and the retention portion are arranged with a transverse overlap, whereby movement of the connector in the second axial direction is limited by the split-dose prevention structure. For the drive tube being arranged in the stop position, the split-dose-prevention structure (184, 284.1, 284.2) and the retention portion are arranged with a transverse clearance and/or an axial gap, whereby the return spring (107, 207) can move the connector in the second axial direction, in response to releasing the applied force in the first direction on the connector.

According to an embodiment, a painless syringe with an anti-slip structure for perforating an alveolar bone and injecting an anesthetic comprises an injecting part having a needle for perforating the alveolar bone and injecting the anesthetic, a holder having a first end coupled with the injecting part and a second end open and empty, an ampoule formed to be inserted into the holder and having a first end into which the needle of the injecting part is inserted and a second end having a piston for discharging the anesthetic, a housing formed to receive the holder and having a through hole to expose the first end of the holder to an outside, and a handpiece coupled with the housing, rotating the ampoule, the holder, and the injecting part to perforate the alveolar bone, and pressing the piston to inject the anesthetic.

The invention relates to a piston rod drive arrangement for an injection device used for self-administration of a plurality of individually set doses. The drive arrangement is made from a first element (10) mating the non-circular cross-section (3) of a piston rod (1) and a second element (20) having an inner thread (21) mating the outer thread of the piston rod. Whenever the first element (10) and the second element (20) are rotated in relation to each other the piston rod (1) is moved in an axial direction. In order to minimise the play in the threaded connection a resilient element (23) is proved to apply a force to the piston rod (1) in a longitudinal direction.

The present disclosure concerns an indication mechanism for an automatic applicator, particularly for insulin or other liquid preparations, particularly for multiple injection administration of set doses of a medicine from an exchangeable container, for example for the self-application of insulin by diabetes patients. An indication mechanism for an automatic applicator, having an assembly of at least two barrels movably coupled to each other has an indication barrel mounted on the driving barrel contains only marking on its external surface and is co-axially connected to the pull-push control nut.

A drug delivery device configured to provide a dose of medicament is disclosed. The drug delivery device includes a main housing, a syringe arranged in the main housing, and a pneumatic power pack arranged in the main housing. The pneumatic power pack includes a pressurized gas source storing pressurized gas, a valve for the pressurized gas source, a sleeve having an inner wall, and a plunger. The sleeve is configured to receive pressurized gas released from the pressurized gas source. The plunger is in sliding gas-tight engagement with the inner wall of the sleeve. Upon activation of the valve, the valve releases the pressurized gas, and the released pressurized gas flows into the sleeve and propels the plunger in a distal direction with respect to the sleeve and the syringe, so as to eject medicament from the syringe.

A system comprises a first member, a second member, and a third member, wherein the first and second members are rotatable relative to the third member, wherein the first and second members are coupled to one another by a dead-angle follower coupling, wherein the dead-angle follower coupling is configured such that the first and second members are rotatable relative to one another, wherein the second and third members are rotationally coupled to one another by a switchable coupling mechanism, wherein the switchable coupling mechanism is switchable between two different states, a locked state and a non-locked state, wherein the maximum torque transferable between the second and third members via the switchable coupling mechanism in the locked state is greater than in the non-locked state, wherein the switchable coupling mechanism is in the locked state when the first member is in a locking position relative to the second member.

An autoinjector includes a housing, a product container, a torsion spring, a drive element, and a propulsion element. In order to discharge liquid out of the product container, the torsion spring rotates the drive element, and the rotating drive element produces a propulsive movement of the propulsion element and of a piston in the product container. A rotation sensor is configured for an alternating continuous detection of at least two rotational positions per revolution of the drive element during the discharge process, and a processor unit is configured for determining the axial position of the piston in the product container from the detected rotational positions.

A drug delivery device configured to provide a dose of medicament is disclosed. The drug delivery device includes a main housing, a syringe arranged in the main housing, and a pneumatic power pack arranged in the main housing. The pneumatic power pack includes a pressurized gas source storing pressurized gas, a valve for the pressurized gas source, a sleeve having an inner wall, and a plunger. The sleeve is configured to receive pressurized gas released from the pressurized gas source. The plunger is in sliding gas-tight engagement with the inner wall of the sleeve. Upon activation of the valve, the valve releases the pressurized gas, and the released pressurized gas flows into the sleeve and propels the plunger in a distal direction with respect to the sleeve and the syringe, so as to eject medicament from the syringe.

The invention relates to a spring driven multi-use fixed dose injection device with an End-of-Content (EoC) mechanism. A housing structure contains a volume of a liquid drug which is expelled in a predefined number of substantially equally sized dose volumes. Each dose volume is expelled automatically with the assistance of a spring which is loaded with a force sufficient to expel the full number of the predefined plurality of predetermined and equally sized dose volumes. Each dose volume is prepared and released by moving a drive element a predetermined axial distance in the proximal direction away from an initial position, followed by a rotation of the drive element by the force of the spring back to the initial position during which rotation the drive element rotates the piston rod to move helically. The End-of-Content mechanism determines how many times the drive element can be moved proximally and comprises a longitudinal track structure associated with the piston rod which has a free length defined by a proximal stop associated with the piston rod which stop prevents the drive element from moving an additional predetermined axial distance in the proximal direction required to prepare a subsequent predetermined dose volume after the predefined plurality of predetermined and equally sized dose volumes have been selected.