An intraosseous needle includes a cylindrical shaft. The cylindrical shaft includes a first portion comprising a plurality of threads protruding from the cylindrical shaft. The cylindrical shaft includes a second portion comprising a plurality of fenestrations, disposed between the first portion and a distal end of the cylindrical shaft, wherein the cylindrical shaft is continuous and smooth within the second portion, and where the continuous, smooth second portion is longer than the first portion. The intraosseous needle also includes a needle head extending from a proximal end of the cylindrical shaft.

An apparatus and method for performing painless bone marrow biopsy that requires only a single procedural pass to the biopsy bone site is disclosed. The biopsy device combines dermatotomy, anesthesia and marrow specimen extraction functionality and inherently aligns the bone drilling site with the site of anesthetic delivery by incorporating a transport channel that may be used for anesthetic delivery, into the biopsy needle used for bone access and bone marrow sample retrieval. The biopsy device also discloses a right angle drill interface and multiple side-access ports for aspiration and anesthetic syringe attachments. A novel syringe/plunger system comprising vacuum tube fitted plungers for quick transfer of marrow specimen sample without requiring a second non-sterile assistant is also disclosed.

A resin hollow needle includes a distal end section including a puncture end portion, a large-diameter section having a diameter greater than that of the distal end section, a tapered section that is located between the large-diameter section and the distal end section, and a hub section. The distal end section includes a hole that is provided on a proximal end side in comparison to a distal end and on a distal end side of the tapered section, and communicates with the inside and the outside of a hollow needle, and a tapered puncture end portion. The distal end section has a total length of 7 to 14 mm and a maximum outer diameter of 1.5 to 3.0 mm. The tapered section has a length of 0.3 to 4.7 mm and a taper angle of 10° to 50°. The large-diameter section has a length of 4 mm or greater, and a distal end outer diameter that is greater than the maximum outer diameter of the distal end section by 0.6 to 3.0 mm.

A system for refilling a multi-chamber implantable infusion device is presented. The infusion device has a refill chamber which is accessible through an external septum of a refill port. The refill chamber is divided by an inner septum into an upper reservoir and a lower reservoir. The lower refill chamber is refilled with lower reservoir needles having a needle opening axially placed to align with the lower reservoir. The upper reservoir is refilled with an upper reservoir needle having an opening aligned with the upper reservoir. Magnetic portions are provided in the needles to localize and identify the needle. A processor within the infusion device is connected to magnetic field sensors which sense magnetic portions of the needle and recognize information encoded magnetically within the needle.

A device for injecting a therapeutic agent into an ocular implant at least partially implanted in an eye including an injection lumen providing a pathway for injecting the therapeutic agent into the implant; an outlet lumen providing a pathway for pre-existing fluid in the ocular implant to exit the implant; and a collection chamber fluidly coupled to the outlet lumen that provides a first fluid outflow resistance and a second fluid outflow resistance. The first fluid outflow resistance is lower than a first resistance to outflow of the implant. The second fluid outflow resistance is greater than a force imparted onto the implant by intraocular pressure of the eye. Injection of therapeutic agent into the implant via the injection lumen causes the pre-existing fluid to exit the implant and enter the collection chamber via the outlet lumen and causes a second pre-existing fluid to displace from the collection chamber.

An injection device for in vivo delivery of an agent includes a tubular body defining a lumen that extends along a central axis that is oriented along a longitudinal direction. A distal end of the lumen is occluded and the tubular body defines at least one side-port extending from the lumen to an outer surface of the tubular body. The at least one side-port is elongated along the outer surface of the tubular body.

The present invention relates to a drug injection device using pulsed shock waves, the drug injection device comprising: a power unit generating pulsed power; a pulsed shock wave generating unit which receives the pulsed power and generates pulsed shock waves; an upper housing in which a liquid and the pulsed shock wave generating unit are disposed; a lower housing which is connected to the upper housing, and in which a drug is disposed; a shock wave transmission unit which is provided between the upper housing and the lower housing to separate the upper housing and the lower housing; and an injection unit which is disposed in the lower housing and inject the drug.

A method for preparing a pre-filled multi-chamber injection system includes providing an injection system body, the injection system body defining an open proximal end, a body interior, and an open distal end. The method also includes introducing a first substance into a distal end of the body interior. The method further includes disposing a distal stopper member in the body interior, the distal stopper member and the injection system body defining proximal and distal chambers in the body interior. Moreover, the method includes introducing a second substance into the body interior. In addition, the method includes disposing a proximal stopper member in the body interior. The method also includes inserting an elongate member at least partially into the body interior, the elongate member having a plurality of flow channels for fluidly coupling the proximal and distal chambers. The method further includes coupling a plunger member to the proximal stopper member.

A puncture apparatus includes: a needle member having a tubular shape and comprising a flexible portion that is deformable; and a puncture assisting member that is movable or deformable in an axial direction of the needle member between: a restricting position in which the puncture assisting member is located outside the flexible portion of the needle member in a radial direction of the needle member, and thereby restricts deformation of the flexible portion, and a permissive position in which the puncture assisting member is not located outside the flexible portion in the radial direction, and thereby permits deformation of the flexible portion. The puncture assisting member is configured to move or deform from the restricting position to the permissive position in conjunction with an operation of inserting the flexible portion into a living body at a time of puncturing the living body with the needle member.

An intraosseous needle assembly includes a needle having a first cylindrical shaft. The shaft having a distal end, a proximal end, and a wall defining an inner channel. The first cylindrical shaft includes threading protruding from the wall along a proximal portion of the first cylindrical shaft. The needle further includes a needle head extending from the proximal end of the first cylindrical shaft. The needle assembly may further include a stylet, the stylet having a second cylindrical shaft having a first end and a second end and a stylet head extending from the second end. The stylet head includes a proximal surface and a distal surface, a pair of substantially parallel second side walls, a pair of rounded end sections joining the second side walls, a protrusion extending from the distal surface, and a tapered section extending from the distal surface to the second cylindrical shaft.