Tumors in portions of a subject's body that have a longitudinal axis (e.g., the torso, head, and arm) can be treated with TTFields by affixing first and second sets of electrodes at respective positions that are longitudinally prior to and subsequent to a target region. An AC voltage with a frequency of 100-500 kHz is applied between these sets of electrodes. This imposes an AC electric field with field lines that run through the target region longitudinally. The field strength is at least 1 V/cm in at least a portion of the target region. In some embodiments, this approach is combined with the application of AC electric fields through the target region in a lateral direction (e.g., front to back and/or side to side) in order to apply AC electric fields with different orientations to the target region.

A wearable device is provided. The wearable device, which is used by being attached to a user's skin, includes a main body unit including a housing and a battery, the battery being arranged inside the housing, an electrode unit including a plurality of electrodes connected to the battery, and a patch unit including one or more conductive members, the one or more conductive members being configured to electrically connect the electrode unit to the user's skin. The patch unit further includes a plurality of stacked layers, and a layer in contact with the user's skin includes a plurality of ventilation holes.

A medical drug devices for transdermal drug delivery systems (TDDS) comprising a novel iontophoretic polymeric microneedle device and its use in administration of drugs.

Improved hydrogel configurations for use with a TTField-generating system is disclosed. Also disclosed are kits containing the improved hydrogel configurations and methods of producing and using the improved hydrogel configurations.

Improved hydrogel configurations for use with a TTField-generating system is disclosed. Also disclosed are kits containing the improved hydrogel configurations and methods of producing and using the improved hydrogel configurations.

Discussed is a hair care appliance including: a first care body having a first care electrode; a second care body having a second care electrode; and a bending unit connected between the first care body and the second care body. The first care body includes a main substrate electrically connected to the first care electrode, and a processor provided at the main substrate, and the second care body includes a battery electrically connected to the second care electrode, and the bending unit includes an elastic housing and a flexible substrate which is accommodated in the elastic housing and which electrically connects the battery to the main substrate.

A method and apparatus to treat hyperhidrosis is provided in which a battery provides a milliampere electrical current to the inside of a waterproof glove containing water and sealed to the user's arm so that circulation is not unduly restricted while the user can raise the water-filled gloves and hands above the user's head without leaking. A tapered portion on the proximal end of each glove is folded inside the glove to seal against the user's arm to form a pocket between the tapered portion which seals against the user's arms, and part of a wrist portion of the glove located radially outward of the tapered portion. When the user's gloves and hands rotate upward, water collects in the pocket(s) while the tapered portion provides a leakproof seal, thus allowing manual manipulation while wearing the water-filled gloves.

The invention provides a variety of novel devices, systems, and methods of utilizing mixed-ionic-electronic conductor (MIEC) materials adapted to function with an applied current or potential. The materials, as part of a circuit, are placed in contact with a part of a human or nonhuman animal body. A sodium selective membrane system utilizing the MIEC is also described.

Described is a low voltage, pulsed electrical stimulation device for controlling expression of klotho, a useful protein, by tissues. Also described are methods of enhancing expression of klotho in cells.

A medical drug devices for transdermal drug delivery systems (TDDS) comprising a novel iontophoretic polymeric microneedle device and its use in administration of drugs.