The present invention relates to an artificial joint comprising a first joint portion (101), a second joint portion (105) and an intermediate portion (103). The first joint portion and the second joint portion each comprise an electrically conductive material and the intermediate portion comprises a non-conductive material and is arranged in between the first joint portion and the second joint portion such that the first joint portion is electrically isolated from the second joint portion. The artificial joint further comprises an internal electronic unit (110) provided inside of the isolating portion being connected to the first joint portion via at least one first electrode (111) and to the second joint portion via at least one second electrode (113). Thus, a first voltage can be applied to the first joint portion and a second electric voltage can be applied to the second joint portion, the voltages being with reference to a common reference potential.

The present invention relates to anti-microbial, antiviral, fibers, and fabrics and to devices made from said fabrics. The invention has particular utility in connection with personal protective equipment (PPE’s) such as surgical masks and respirators, and will be described in connection with such utilities, although other utilities are contemplated, including, for example for forming air handling filters for people movers, i.e., automobiles, trucks, buses, trains, ships and planes, as well as for forming filters for air handling equipment for buildings.

A skin care device according to an embodiment of the present disclosure includes a substrate; a case for covering surface of the substrate; and at least one galvanic current application device electrically connected to the substrate, in which each of the at least one galvanic current application device includes a contact head that forms a contact surface with respect to a user's skin and is electrically connected to the substrate; and a holder provided between the substrate or the case and the contact head, and in which the holder includes an elastic fixing body elastically fixing the contact surface of the contact head to a position spaced apart from the case by a predetermined length.

An unattended approach can increase the reproducibility and safety of the treatment as the chance of over/under treating of a certain area is significantly decreased. On the other hand, unattended treatment of uneven or rugged areas can be challenging in terms of maintaining proper distance or contact with the treated tissue, mostly on areas which tend to differ from patient to patient (e.g. facial area). Delivering energy via a system of active elements embedded in a flexible pad adhesively attached to the skin offers a possible solution. The unattended approach may include delivering of multiple energies to enhance a visual appearance.

A cosmetic method for treating a skin of a person is presented, the method comprises inserting one or more needles to one or more depths into the skin of the person such that at least a tip of at least one needle of the one or more needles is deployed within a muscle layer of the person's skin; applying a negative DC voltage to the one or more needles, while a skin of the person is in contact with a positive electrode to form one or more closed circuits of DC current through the person's body; and providing the DC current for a pre-selected amount of time to damage and/or ablate muscles and/or muscle nerve cells in the muscle layer; thereby providing a skin treatment comprising reducing and/or smoothing wrinkles from the person's skin.

Disclosed are apparatus, compositions, and methods for promoting regeneration of tissue on a subject such as a wounded, damaged, or injured appendage, or within a subject such as a wounded, damaged, or injured organ. The disclosed apparatus, composition, and methods include or utilize wearable sleeves and regenerative compositions.

An apparatus for use with a needle electrode assembly used to disrupt biofilm from an implanted metallic object, such as a replacement orthopedic appliance, includes a body that retains the needle electrode assembly including a projecting needle portion projecting from a lower end of the body. A needle adjustment mechanism enables the length of the projecting needle portion to be adjusted, the needle adjustment mechanism including a spring element within the apparatus body and attached to the needle electrode assembly. The spring element has a substantially nonvariable spring constant such that constant pressure is applied to the needle electrode irrespective of the length of the needle electrode to be brought into contact with the skin of a subject and implanted metallic object, once released by the needle adjustment mechanism. The apparatus includes a plurality of supports that enable the apparatus to be attached to the skin of a subject during treatment wherein a retraction mechanism enables the needle to be withdrawn into the apparatus and a locking mechanism enables safe encapsulation and retention of the needle within the apparatus after treatment.

An electrophysiology system for removing an excess of ions from a predetermined area of a patient's body. The system includes an electric signal source configured to generate an electric signal, a plurality of electric channels connected to the electric signal source and a controller. Each channel includes an electric signal emitter and an electric signal receiver. A signal path may be created therebetween. Such signal path is to be passed through the lymphatic system of a patient to move an excess of ions. The controller is configured to operate in an operational mode. The controller operating in the operational mode is configured to: send a first electric test signal, measure the first electric test signal, compare the measured first electric test signal and the sent first electric test signal, indicate the result of the comparison and apply a first treatment electric signal based on the comparison.

Pulsed electric fields (PEFs) are transmitted to a body lumen or passageway in a manner which provides focal therapy. In some embodiments, PEFs are delivered through independent electrically active electrodes of an energy delivery body, typically in a monopolar fashion. Such delivery concentrates the electrical energy over a smaller surface area, resulting in stronger effects than delivery through an electrode extending circumferentially around the lumen or passageway. It also forces the electrical energy to be delivered in a staged regional approach, mitigating the effect of preferential current pathways through the surrounding tissue. Focal delivery of PEFs can provide increased tissue lethality by employing precise timing and sequencing of energy delivery to the electrodes.

A system for preventing thrombosis in an implantable medical device includes an implantable medical device sized for implantation at least partially within a patient's body. The device includes an at least partially electrically conductive portion that is disposed within a patient's body upon implantation, an electrode coupled to the electrically conductive portion of the device; and a power source coupled to the electrode. The power source provides a negative electric charge to the at least partially electrically conductive portion for an indefinite period of time. The device may be configured to resist thrombosis, infection, and/or undesired tissue growth via the charged conductive portion once implanted. Exemplary embodiments of the implantable medical device include a hemodialysis vasculature graft, a dialysis catheter, a coronary artery, and a heart valve.