This disclosure relates generally to medical devices, systems, and methods for activation of a photoactive agent during a medical procedure. In an aspect, a catheter system for activation of a photoactive agent may comprise a catheter comprising an elongate shaft comprising a proximal portion, a distal portion, and a first lumen extending along the elongate shaft. A first flexible circuit may be disposed about the distal portion of the elongate shaft. A plurality of first light-emitting diodes (LEDs) may be disposed along the first flexible circuit. A second flexible circuit may be disposed about the distal portion of the elongate shaft. A plurality of second LEDs may be disposed along the second flexible circuit. A control unit may be coupled to the proximal end of the elongate shaft. The communications cable may be disposed within the catheter and may electrically couple the first LEDs with the control unit.

The present disclosure describes a wellness application for digital usage comprising at least one software program that identifies the level of high energy visible light reduction provided by the thin film; and a dosimeter for sending data about ionizing radiation to the software. The software tracks the total time of device usage and determines wherein the software, based on a dosimeter measurement received from the dosimeter, communicates with at least one processor to execute at least one of: determine a notification for reducing exposure to high energy visible blue light about divide user interface, and adjust the display output by at least one of adjusting a color contrast and brightness, taking into account the level of visible light coverage and total time of device usage.

The present invention relates to a hybrid imaging system for photodiagnosis and phototherapy and, more particularly, to a hybrid imaging system for photodiagnosis and phototherapy, which simultaneously acquires a visible ray image or a near-infrared ray image and a lonq wave infrared ray image by using an optical method. The hybrid imaging system for photodiagnosis and phototherapy according to the present invention includes a light distribution unit, a visible ray/near-infrared ray measurement unit, a long wave infrared ray measurement unit, and a light source unit, thereby simultaneously and quickly extracting a visible ray image, a near-infrared ray image, and a long wave infrared ray image without mutual distortion.

Periodontal disorders such as disorders associated with a dental implant are treated with a laser where an average laser power along with other laser parameters provide particular settings for the treatment, the treatment including one or more of creating a gingival trough or flap around the implant, ablating or denaturing infected tissue via photothermolysis, lasing a pocket around the affected implant, and compressing marginal tissues against the implant.

An optical stimulation system includes a light source configured to produce light for optical stimulation; a light monitor; an optical lead coupled, or coupleable, to the light source and the light monitor; and a control module coupled, or coupleable, to the light source and the light monitor. The control module includes a memory, and a processor coupled to the memory and configured for receiving a request for verification or measurement of a light output value; in response to the request, receiving, from the light monitor, a measurement of light generated by the light source; and, based on the measurement, reporting a response to the request.

A treatment apparatus and a treatment method capable of minimally invasively specifying a lesion extent and checking progress of treatment while performing the treatment for destroying tumor cells. The treatment apparatus that detects and destroys a tumor cell by irradiating an antibody-photosensitive substance adsorbed on a tumor cell membrane with excitation light includes: an elongated tubular shaft having optical transparency; a light irradiation unit configured to emit the excitation light of the antibody-photosensitive substance from an inside of the shaft in a side direction perpendicular to an axial direction of the shaft; and a side direction fluorescence detection unit configured to detect, from the side direction perpendicular to the axial direction of the shaft, fluorescence emitted by the excited antibody-photosensitive substance, and movable in the axial direction with respect to the shaft.

A device that is connectable to a phototherapy apparatus for applying targeted phototherapy to an area of skin to place a skin condition into remission and a method of determining a maximum tolerable dose of phototherapy applied to a treatment area to determine an optimum therapeutic dose to quickly place a skin condition into remission. The dosimetry device can include a housing and an optical matrix arranged within the housing. The optical matrix includes a plurality of at least one of absorptive, reflective and/or partially transmissive regions that each permits a different percentage of light to be delivered to an individual's skin. An assessment can then be made as to the maximum tolerable dose of phototherapy that can be applied to the individual's skin in order to place a skin condition into remission.

According to the invention, there is provided a light-based skin treatment device comprising a treatment light source; a treatment light exit window via which, during operation, treatment light generated by the treatment light source is applied to skin of a user, wherein the treatment light exit window comprises an optically transparent material arranged to contact the skin during operation; and an imaging unit comprising an image sensor 5 arranged to generate an image of the skin during operation. The skin treatment device further comprises an optical waveguide comprising a treatment light receiving surface, an imaging light exit surface and a main surface, wherein said treatment light receiving surface is arranged to receive the treatment light so that the treatment light enters the waveguide at the treatment light receiving surface; said main surface comprises the treatment light exit 10 window and is arranged to transmit the treatment light so that the treatment light exits the waveguide at the treatment light exit window; said imaging light exit surface is arranged with respect to the main surface to receive light reflected at the main surface by total internal reflection at positions where, during operation, no skin is in contact with the main surface; said image sensor is arranged to receive from the imaging light exit surface light which is 15 guided by total internal reflection from the main surface towards the imaging light exit surface.

A photodynamic therapy treatment support device is provided with a light source and a distribution information output unit. The light source irradiates a photosensitive substance administered to a body of a subject with light of a specific wavelength bandwidth having energy capable of generating fluorescence from the photosensitive substance without advancing necroses of tumor cells. The distribution information output unit outputs information on a distribution state of the fluorescence generated from the photosensitive substance, based on the fluorescence generated from the photosensitive substance.

A method includes providing a pixelated surface, providing at least one sensor configured to track movement of at least one eye of a user relative to the surface, detecting one or more portions of the surface based on the tracked movement and adjusting one or more properties in relation to the one or more detected portions such that a dosing of one of cyan and long-red, near-infrared (NIR) illumination is provided, while the user is gazing at the one or more portions.