An LED exterior luminaire comprising light-emitting diodes (LEDs) with a circadian-adjustable light output mode for its medical safety comprises at least two switchable LED chip chains I and III, wherein chain I comprising at least one LED chip emitting orange light from a wavelength range of 580 nm to 610 nm and at least one LED chip emitting red light from a wavelength range of 610 nm to 700 nm, chain III comprising at least one blue LED chip overlaid with a luminophore emitting a continuous band spectrum of visible light from a wavelength range of 440 nm to 700 nm and a correlated color temperature CCT of 2200 to 4200 K, wherein chains I and III are each separately connected to a power source via a dimming ballast that regulates the proportion of input current to each chain separately.

Lighting systems, methods, and devices for protecting human circadian neuroendocrine function during night use are described. Suitable lighting conditions can be provided for a working environment while protecting the circadian neuroendocrine systems of those occupying the illuminated workplace during the night. Lighting systems, methods, and devices can provide substantive attenuation of the pathologic circadian disruption in night workers. Lighting systems, methods, and devices can attenuate the specific bands of light implicated in circadian disruption. LED lighting systems, methods, and devices can provide increased intensity at a different portion of the spectrum than conventional LEDs, providing a useable white light even when unfavorable portions of the wavelength are attenuated by a notch filter. LED lighting systems, methods, and devices can switch between a daytime configuration and a night time configuration, wherein the daytime configuration provides unfiltered light and the night time configuration provides filtered light.

Lighting systems, methods, and devices for protecting human circadian neuroendocrine function during night use are described. Suitable lighting conditions can be provided for a working environment while protecting the circadian neuroendocrine systems of those occupying the illuminated workplace during the night. Lighting systems, methods, and devices can provide substantive attenuation of the pathologic circadian disruption in night workers. Lighting systems, methods, and devices can attenuate the specific bands of light implicated in circadian disruption. LED lighting systems, methods, and devices can provide increased intensity at a different portion of the spectrum than conventional LEDs, providing a useable white light even when unfavorable portions of the wavelength are attenuated by a notch filter. LED lighting systems, methods, and devices can switch between a daytime configuration and a night time configuration, wherein the daytime configuration provides unfiltered light and the night time configuration provides filtered light.

A light-emitting device (100) is disclosed. The light-emitting device (100) comprises a plurality of light-emitting elements (135) or light sources and a power module (120) adapted to selectively convey, supply or provide electrical power to the light-emitting elements (135). The power module (120) may be dimensioned such as to be able to power only a proper subset of the light-emitting elements (135) of the light-emitting device (100) at a given time, the subset having a maximum number of light-emitting elements (135) included therein with respect to the number of light-emitting elements (135) included in the all subsets of the light-emitting elements (135) of the light-emitting device (100). The plurality of sets of light-emitting elements (135) may be arranged so as to emit light over a light emission area, and the plurality of sets of light-emitting elements (135) may be arranged relatively to each other such that different sets of light-emitting elements (135) emit light over different portions of the light emission area.

A feedback energy-release system and operation method thereof are provided, adapted to provide an energy parameter to an energy-release apparatus for performing a plurality of energy-release operations on a target skin. A feature capturing device captures tissue feature data of the target skin, wherein the tissue feature data captured before and after each energy-release operation are a first and a second tissue feature data, respectively. A control device compares the second tissue feature data with a plurality of reference tissue feature data to obtain at least one suggested energy parameter, determines grades of the tissue feature data of the current energy-release operation and records a grade distribution of the tissue feature data. The control device generates the energy parameter of the next energy-release operation according to a difference between the first and second tissue feature data, the at least one suggested energy parameter and the grade distribution.

Methods of treating skin disorders are disclosed. The methods involve impinging light having a first peak wavelength on the tissue at a first radiant flux, wherein the first peak wavelength and the first radiant flux is selected to provide an anti-inflammatory effect, and impinging light having a second peak wavelength on the tissue at a second radiant flux, wherein the second peak wavelength and the second radiant flux are selected to either stimulate enzymatic generation of nitric oxide to increase endogenous stores of nitric oxide or release nitric oxide from the endogenous stores are disclosed. Representative skin disorders include pruritus, psoriasis, acne, rosacea, and eczema, and the skin can include the scalp. The methods can reduce stinging and/or itching associated with the skin disorder. The anti-inflammatory wavelengths can be in the range of between about 650 and about 680 nm.

A phototherapy device (100) and a phototherapy instrument (500), comprising a near infrared irradiation module (110) used for emitting near infrared light to the head, and a control component (120) used for controlling the operation of the near infrared irradiation module (110) and coupled to the near infrared irradiation module (110). A method for using near infrared light for therapy, which comprises applying a first, optional second, optional third or more near infrared lights to the head of a patient. The device and method are used for treating Alzheimer's disease, improving brain mitochondrial function and ATP levels, promoting amyloid beta protein (Aβ) decomposition, reducing Aβ deposition, reducing damage to nerve cells, improving nerve tissue repair and regeneration capabilities, improving cognitive ability etc. A therapy method using the phototherapy device (100) or the phototherapy instrument (500), and a computer readable recording medium controlling required near infrared light.

This disclosure relates generally to medical devices, systems, and methods for activation of a photoactive agent during a medical procedure. In an aspect, a catheter system for activation of a photoactive agent may comprise a catheter comprising an elongate shaft comprising a proximal portion, a distal portion, and a first lumen extending along the elongate shaft. A first flexible circuit may be disposed about the distal portion of the elongate shaft. A plurality of first light-emitting diodes (LEDs) may be disposed along the first flexible circuit. A second flexible circuit may be disposed about the distal portion of the elongate shaft. A plurality of second LEDs may be disposed along the second flexible circuit. A control unit may be coupled to the proximal end of the elongate shaft. The communications cable may be disposed within the catheter and may electrically couple the first LEDs with the control unit.

Photobiomodulation therapy systems provide a highly effective way to treat many common ailments to the human body. Many embodiments described herein enable two or more light therapy devices to be communicatively coupled together in various ways. In some embodiments, the light therapy system includes a first light device and a second light device arranged and configured to be communicatively coupled to the first light device. Each of the light devices may include a housing, a communication module, and a plurality of lights arranged and configured to emit at least one of red light and near infrared light.

A light therapy bed including multiple LEDs positioned in individually controllable modules is disclosed. The modules of LEDs are configured to have direct contact or in close proximity to the skin or tissue of the user, through an acrylic or similar cover. The LEDs light the surface and underlying layers of tissue for photodynamic stimulation of the cells. Iterations of the device utilize light known to have a bactericidal effect in the case of acne, MRSA, etc. The bed is fabricated and formed in a curved configuration to optimize contact between the LEDs and the skin of a user. Each of the LED modules may be mounted with a PCB in an arrangement to provide even lighting and temperature upon the skin or tissue surface of a user. Each module also has one or more thermal sensors that evenly and quickly heat all of the areas of a user's body.