A dose planning system, which takes the drug concentration distribution in human organs/tissues as well as the atomic composition distribution of human organs/tissues into consideration, and calculates the neutron/photon dose distribution in human organs/tissues under this drug concentration distribution using the Monte Carlo Method. Thereby the neutron/photon dose distribution in the organs/tissues of the human subject is calculated more accurately.

A beam shaping assembly for neutron capture therapy includes a beam inlet, a target having nuclear reaction with an incident proton beam from the beam inlet to produce neutrons forming a neutron beam, a moderator adjoining to the target, a reflector surrounding the moderator, a thermal neutron absorber adjoining to the moderator, a radiation shield arranged inside the beam shaping assembly and a beam outlet. The material of the moderator is subjected to a powder sintering process using a powder sintering device so as to change powders or a power compact into blocks. The reflector leads the neutrons deviated from the main axis back. The thermal neutron absorber is used for absorbing thermal neutrons so as to avoid overdosing in superficial normal tissue during therapy. The radiation shield is used for shielding leaking neutrons and photons so as to reduce dose of the normal tissue not exposed to irradiation.

A beam shaping assembly (10) used in a neutron capture system and capable of changing an irradiation range of a neutron beam. The beam shaping assembly includes: a beam inlet (11), a target (12), a moderator (13) adjoining the target (12), a reflector (14) surrounding the moderator (13), a thermal neutron absorber (15) adjoining the moderator (13), a radiation shield (16) arranged inside the beam shaping assembly (10), and a beam outlet (17). The beam shaping assembly (10) further includes replacement components (21, 22) that can be attached to and detached from the beam shaping assembly (10) to change the irradiation range of the neutron beam.

A method for measuring radiation intensity includes measuring the radiation intensity received by the protein in a radiation field based on degree of protein degradation in the radiation field, wherein the degree of degradation is a ratio of the molecular weight of the protein before and after irradiation. The measuring method is simple in operation, small in number of steps, small in error, and capable of measuring radiation doses of various radiation fields or even mixed radiation fields. Use of a biological dosimeter for measuring the radiation intensity by the method in a neutron capture therapy system can not only assess radiation contamination in the irradiation chamber, but also evaluate the neutron dose.

A radioactive ray radiation system includes a beam radiation apparatus, a treatment planning module, a control module, a preparation room and a radiation room. First and second stereoscopic vision apparatuses are respectively arranged in the preparation room and the radiation room. Simulated positioning is performed on a radiated subject in the preparation room according to the location of a radiated part determined in a treatment plan, and a first image of the radiated part collected by the first stereoscopic vision apparatus is compared with the treatment plan to determine a simulated positioning pose. Radiation positioning is performed on the radiated subject in the radiation room according to the determined simulated positioning pose, and a second image of the radiated part collected by the second stereoscopic vision apparatus is compared with the treatment plan to control the beam radiation apparatus to start performing radiation therapy on the radiated subject.

Design and making methods of a neutrons generating target are described. In some embodiments, a surface of a target substrate can be modified to form one or more surface features. In some embodiments, a neutron source layer can be disposed on the surface of the target substrate. In some embodiments, the neutron source layer and the target substrate can be heated to an elevated temperature to form a bond between the two. In some embodiments, the surface modification of the target substrate can reduce blistering and material exfoliation in the target. The target can be used in boron neutron capture therapy.

A neutron capture therapy apparatus includes a neutron beam irradiation system, a detection system and a monitoring system. The neutron beam irradiation system is configured for generating a neutron beam. The detection system is configured for detecting real-time irradiation parameters during a neutron beam irradiation therapy process. The monitoring system is configured for controlling the whole neutron beam irradiation process and includes an input part for inputting preset irradiation parameters, a determination part for determining whether the irradiation parameters need to be corrected and a correction part for correcting some of the irradiation parameters when the determination part determines that the irradiation parameters need to be corrected. When the ratio of the real-time neutron dose detected by the detection system to a preset neutron dose is greater than or equal to a preset value, the determination part of the monitoring system determines that the irradiation parameters need to be corrected.

A neutron capture therapy system, including a vacuum tube for transmitting a charged particle beam, a neutron generating part for generating a neutron beam, and a beam shaping assembly for shaping the neutron beam. The beam shaping assembly is provided with an accommodating part. The neutron generating part is disposed at an end of the vacuum tube. The vacuum tube has a first position and a second position. The neutron capture therapy system further includes a removal device, which includes a moving part that drives the vacuum tube to move. The moving part has a third position and a fourth position. When the moving part is in the third position, the vacuum tube is in the first position. When the moving part is in the fourth position, the vacuum tube is in the second position, and the neutron generating part is located at the outer side of the beam shaping assembly.

Embodiments of systems, devices, and methods relating to a beam system. An example beam system includes a charged particle source configured to generate a beam of charged particles, a pre-accelerator system configured to accelerate the beam, and an accelerator configured to accelerate the beam from the pre-accelerator system. The pre-accelerator system can cause the beam to converge as it is propagated from the source to an input aperture of the accelerator. The pre-accelerator system can further reduce or eliminate source disturbance or damage caused by backflow traveling from the accelerator toward the source.

A heat dissipation structure includes a housing. The housing has a bottom surface, a liquid inlet channel, a liquid outlet channel and a protruding portion. The liquid inlet channel and the liquid outlet channel are located at two opposite ends of the housing and above the bottom surface. The liquid inlet channel and the liquid outlet channel extend along a first direction. The protruding portion is located between the liquid inlet channel and the liquid outlet channel and above the bottom surface. The protruding portion protrudes towards a direction away from the bottom surface. The protruding portion has a protruding surface facing away from the bottom surface. A distance between the protruding surface and the bottom surface is increased first and then decreased along the first direction.