Embodiments of the present disclosure include a method for treating a condition of a subject. An implant defining a longitudinal axis is implanted between a nerve and skin of the subject. The implant includes an insulating member disposed, along the longitudinal axis, on at least a skin-facing side of the implant. Exactly two electrodes are disposed, along the longitudinal axis, at respective portions of a nerve-facing side of the implant. While the electrodes are driven to apply a treatment that stimulates the nerve, the insulating member is used to inhibit direct stimulation of sensory nerve fibers of the skin that are adjacent to the skin-facing side of the implant. Other embodiments are also described.

Embodiments of the present disclosure include a method for treating a condition of a subject. An implant defining a longitudinal axis is implanted between a nerve and skin of the subject. The implant includes an insulating member disposed, along the longitudinal axis, on at least a skin-facing side of the implant. Exactly two electrodes are disposed, along the longitudinal axis, at respective portions of a nerve-facing side of the implant. While the electrodes are driven to apply a treatment that stimulates the nerve, the insulating member is used to inhibit direct stimulation of sensory nerve fibers of the skin that are adjacent to the skin-facing side of the implant. Other embodiments are also described.

A method for determining a change of temperature of an object. The method may include heating an object and measuring scattering parameters (S-parameters) of scattered microwave electric fields from the object. A distorted Born iterative method may be used to determine a change of a dielectric property of the object based on the measured S-parameters. A change of temperature of the object may be determined based on the change of the dielectric property of the object.

Methods for treating urinary stress incontinence by non-invasively delivering energy to one or more submucosal regions of vaginal tissue to induce remodeling within the vaginal tissue are provided. In some embodiments, the energy delivery results in heating of the target tissue to a temperature that ranges from about 38° C. to about 46° C. In some embodiments, the subject methods involve cooling a mucosal epithelial layer over the vaginal tissue. In some embodiments, a reverse thermal gradient is produced as the mucosal epithelium is cooled while energy is delivered to the underlying vaginal tissue.

The invention relates to a device (10) comprising at least one housing (2) having a heat source (1), and at least one strand (11, 12) forming a more flexible pad than the housing (2). The strand (11, 12) comprises two layers (14, 19) of heat-conducting material and a layer (18) of phase change material situated between the two layers of heat-conducting material.

Ferritin or iron-based image enhancement agents identify target tissue for treatment or ablation and are heated by microwave absorption. Microwave heat substrates enhance microwave hyperthermal ablation treatment, and may be percutaneously delivered and imaged by x-ray CT during placement of the microwave treatment antenna, allowing more precise positioning and more complete ablation of a tumor site. One method of treating a target tissue uses image-guided delivery of a heat substrate with a reverse-phase change polymer, and may apply energy to fix a mass of the material in the tissue. The fixed polymer may increase hyperthermia, form a thermal boundary, or blockade a vessel or passage so as to reduce or prevent undesired conductive cooling by contiguous tissue, or may deliver a localized treatment drug at the site, upon heating or as it degrades over time.

A dual-mode microwave applicator for treating tissue comprises a control unit, a rod-shaped element, a coaxial line, and a metal sleeve. The control unit controls the applicator in an application mode and a sensing mode. In the application mode microwave radiation is applied and during the sensing mode tumorous tissue is detected. The rod-shaped element comprises a tip. The coaxial line is formed in the rod-shaped element to relay microwaves to the tip for treatment of the tissue. The coaxial line comprises an inner conductor and an outer conductor. The outer conductor includes a slot of a slot length formed at a slot distance from the tip. The metal sleeve at a sleeve distance from the slot. The sleeve distance is about 0.55 mm, the slot length is about 1.75 mm, and the slot distance is about 7.7 mm.

Systems and methods are disclosed for treating back pain associated with a vertebral body of a patient. The system may include an external energy source configured to be positioned at a location external to the body of the patient, a linear configured to drive translation of the external source in one or more axes, a computer coupled to the external source and linear drive and programming executable on said computer for determining a target treatment site within or near the vertebral body based on acquired imaging data, positioning a focal point of the external energy source to substantially coincide with the target treatment site, and delivering a treatment dose of therapeutic energy at said target treatment site, wherein the treatment dose is configured to modulate a nerve within or near the vertebral body.

Provided herein are systems, devices and methods for the treatment of fungus. In particular, provided herein are systems, devices and methods employing energy to nail and tissue structures to treat fungal infection.

Provided herein are systems, devices and methods for the treatment of fungus. In particular, provided herein are systems, devices and methods employing energy to nail and tissue structures to treat fungal infection.