A minimal ingredient personal care composition containing 9 wt % to 16 wt % amino acid surfactant, 3 wt % to 10 wt % glyceryl ester, 0.2 wt % to 6 wt % triglyceride oil, a liquid carrier. The personal care composition is substantially free of sulfated surfactants, has a pH of 4.5 to 6 and a yield stress of 0.5 to 10 Pa. The personal care composition can be a shampoo that delivers suitable cleaning, color retention and/or conditioning benefits, while also being sulfate free.

The invention provides an antimicrobial personal cleansing composition comprising: (i) an aqueous continuous phase including one or more anionic cleansing surfactants; (ii) a dispersed phase including dispersed particles of zinc pyrithione (ZPT); (iii) a structuring polymer for the aqueous continuous phase which is selected from crosslinked alkali-swellable acrylic emulsion (ASE) polymers; and (iv) from 3 to 20 wt % niacinamide based on the total weight of the composition, wherein the structuring polymer is selected from crosslinked copolymers of (meth)acrylic acid with one or more C1 to C5 alkyl esters of (meth)acrylic acid.

Suggested is a method for making and using an extract of halophytes or psammophilous plants comprising the steps of contacting the plant materials with a solvent, re moving the dissolved extract from the residue, recovering the extract and topically or orally administering the extract to a patient in need of dysfunctions of skin and hair.

A hair care composition is disclosed comprising a polyhydroxy fatty acid amide surfactant of general formula (I) wherein R.sup.1 is a C.sub.1-C.sub.4 alkyl groups or hydroxy-substituted C.sub.1-C.sub.4 alkyl groups; R.sup.2CO is a linear or branched, saturated or unsaturated C.sub.12-C.sub.18 acyl group, a silicone compound, and from 0.01 to 10% by weight of an anti-dandruff agent selected from piroctone olamine, azole based anti-fungal agents and mixtures thereof.

Unique foamable vehicles or carriers comprising at least one wax, waxy substance, counterpart or derivative, a stabilizer, water, and a propellant are provided. In some embodiments, the wax is a liquid wax. In some embodiments, the wax includes a solid wax and a liquid wax. The compositions are substantially free of crystals. The components are selected to provide a composition that is substantially resistant to aging and to phase separation, and/or can substantially solubilize and or stabilize active ingredients. Pharmaceutical and cosmetic compositions with potentially enhanced skin delivery and their uses are also provided.

A hair care composition that removes calcium fatty carboxylate salts from the hair and scalp is provided. The hair care composition includes a calcium chelant, an anionic surfactant, a hydrotrope, a carrier, and optionally a zwitterionic surfactant.

The present invention is directed to a method of treating a fungal infection comprising administering topically, to a subject in need thereof, an anti-fungal effective amount of roflumilast. Preferably, topically administered roflumilast is used to treat fungal infections, fungal growth of and/or hypersensitivity to the fungi Malassezia spp. Patients may also be suffering from seborrheic dermatitis, dandruff, dupilumab facial redness, Tinea versicolor, Pityriasis versicolor, Tinea circinata, Tinea pedis, Tinea unguium, Tinea manus, Tinea cruris, Tinea corporis, Tinea faciei, Tinea capitis, and/or Tinea incognito. Topically administered roflumilast is a quick and effective antifungal agent and presents a viable alternative to current antifungal treatments.

A natural edible shampoo and preparation method thereof, the components comprises fatty acyl lactyl-lactic acid, arginine, vegetable oleic acid monoglyceride, plant phospholipid, ε-polylysine, ethyl lauroyl arginate hydrochloride, inulin, polyol and so on. It resist static electricity, improve the smoothness of hair, prevent pore clogging, and has good flowability at a low temperature. The shampoo overturns the classic concept of existing cationic hair care (large irritation), uses nearly non-irritant natural anionic wash and care main ingredients, relies on a non-enclosed protein peptide/low HLB value oiliness agent film-forming smoothing system, avoids a cationic polymer/silicone oil hair-care pattern with intensive negative effect, and protects the original ecological environment of hair and scalp, so that a final product gains the smooth experience feeling of organic silicone oil, thereby creating a new path for research and development of food and cosmetic-type wash and care two-in-one shampoos.

The present invention is directed to a personal composition comprising a) a strobilurin; b) salicylic acid wherein the ratio of a:b is from about 1:1 to about 100:1; wherein there is a synergistic anti-inflammatory/cellular stress activity.

Aspects of the present invention relate inter alia to compositions which may have utility as anti-microbials. Such antimicrobial compositions may be for use in promoting wound healing and/or the treatment of microbial infections. In certain embodiments, the invention relates to an antimicrobial composition and/or combinations comprising copper gluconate and zinc gluconate which may be for use in treating and/or preventing infections and/or promoting wound healing. Certain aspects of the present invention further elate to an antimicrobial composition and/or device comprising copper gluconate, zinc gluconate and Lactobacillus plantarum for use in treating infections and/or promoting wound healing. Also encompassed by the present invention are methods of treating microbial and/or fungal infections in a subject, for example infections of the genital tract. Aspects of the present invention include a composition comprising a zinc salt and a copper salt, wherein the zinc salt is zinc gluconate and the copper salt is copper gluconate.