The disclosure relates to a method for separation and purification of N-acetyl-glucosamine, and belongs to the technical field of biological engineering. In the disclosure, a raw material solution containing N-acetyl-glucosamine is obtained by microbial fermentation or by hydrolyzing the chitin. The raw material solution is subjected to flocculation pretreatment, and continuous centrifugation or pressure filtration is performed to remove suspended solids such as microorganisms, proteins and polysaccharides to obtain clear liquid. Double-stage ion exchange chromatography is performed to remove impurities such as charged organic molecules and inorganic salts. Membrane concentration is performed to efficiently remove water to improve the concentration of the target product. Spray drying or further evaporation concentration and crystallization are performed. Finally drying is performed to obtain an N-acetyl-glucosamine crystal of which the purity is more than 99%.

The present invention relates to the isolation and purification of sialylated oligosaccharides from an aqueous medium in which they are produced.

A purification device for water has a housing with a longitudinal axis, an upper and a lower end and a substantially round cross section. The device includes a first receptacle, arranged parallel to the longitudinal axis of the housing, for a first purification medium, and a second receptacle, which is also arranged parallel to the longitudinal axis of the housing, for a second purification medium. The receptacle for the second purification medium is arranged eccentrically with respect to the longitudinal axis of the housing.

The present disclosure is directed to ion-exchange systems and devices that can monitor key parameters related to the performance of the ion-exchange device. Specifically, the ion-exchange systems and devices disclosed herein can provide real time voltage drop across groups of membrane pairs using diagnostic spacer borders between the pairs. In addition, the ion-exchange systems and devices disclosed herein can monitor the compression force applied by the compression plates holding the ion-exchange systems and devices together.

The present disclosure provides improved systems and methods for purifying and/or concentrating lentiviral compositions.

A filtering device is for obtaining a chemical liquid by purifying a liquid to be purified, and the filtering device has an inlet portion, an outlet portion, a filter A, at least one filter B different from the filter A, and a flow path which includes the filter A and the filter B arranged in series and extends from the inlet portion to the outlet portion, in which the filter A has a porous base material made of polyfluorocarbon and a coating layer which is disposed to cover the porous base material and contains a resin having an adsorptive group.

A method for process a chemical liquid is provided. The method includes at least providing a system having at least one filtration medium, treatment the system with a treatment liquid having a content of iron (Fe) and calcium (Ca) of about 10 ppb or less, and processing a chemical liquid using an apparatus having the system configured therein after the treatment process.

A ultrapure water supply system 10 includes a pure water tank 16 provided vertically below a use point 30, a return pipe 32 through which ultrapure water is returned from the use point 30 to the pure water tank 16, a first pressure regulating valve 40 that is provided at a first position H1 of the return pipe 32 and adjusts a first pressure upstream of the first position H1 and a second pressure regulating valve 42 that is provided at a second position H2 downstream of the first position H1 and vertically below the first position H1 of the return pipe 32 and adjusts a second pressure downstream of the first position H1 and upstream of the second position H2.

A purification method for separating and purifying an organic solvent from a liquid mixture of an organic solvent and water, the organic solvent having a boiling point of more than 100° C. at 1 atm, includes the steps of: passing the liquid mixture through a first ion exchange device; supplying the liquid mixture discharged from the first ion exchange device to a pervaporation device to selectively separate water component; supplying the organic solvent recovered from the concentration side of the pervaporation device to an evaporator to obtain a purified organic solvent; and passing, through the second ion exchange device, a portion of liquid containing the organic solvent and flowing at a first position subsequent to the first ion exchange device. The liquid discharged from the second ion exchange device is returned to a second position which is at a preceding stage of the pervaporation device.

A high salinity water purification system and process, including a forward osmosis system and a reverse osmosis or nanofiltration system. A concentrated brine of a zinc or iron complex combined with a salt or acid draws pure water across the FO membrane from the influent water. The diluted brine is pumped through a vessel holding an anionic adsorption media to remove the zinc or iron complex and the resultant brine is passed through the RO or nanofiltration system to obtain purified water and a concentrated brine stream. The adsorption media is regenerated by a rinse cycle using fresh water or water from the RO system, removing the zinc or iron complex adhered to the media. The resultant brine is stored and mixed with the output of the RO system. Charged membrane can be used as a standalone membrane in FO process or in combination with resin or resin embedded membrane.