Spin columns that include a poly(acid) membrane separation matrix are provided. Also provided are kits that include the subject devices, as well as methods of using the devices, e.g., in sample preparation (such as protein purification) protocols.

A method of obtaining a compound may include adding a substrate to a medium in a reactor, and reacting the substrate in the reactor to form the compound. A first stream is separated from the reaction liquid through a first membrane. A second stream is separated from the reaction liquid through a second membrane. The first membrane is a filtration membrane and the second membrane is configured for liquid-gas or liquid-liquid extraction The first membrane and the second membrane are at least partially immersed in the medium and are moved relative to the reactor during the separation steps.

A method of obtaining a compound may include adding a substrate to a medium in a reactor, and reacting the substrate in the reactor to form the compound. A first stream is separated from the reaction liquid through a first membrane. A second stream is separated from the reaction liquid through a second membrane. The first membrane is a filtration membrane and the second membrane is configured for liquid-gas or liquid-liquid extraction The first membrane and the second membrane are at least partially immersed in the medium and are moved relative to the reactor during the separation steps.

A device for filtering liquids includes a tank, a tank inlet for introducing a liquid to be filtered into the tank, a tank outlet for a retentate, and at least one rotor rotatably drivable around a tank axis, the at least one rotor having a hollow shaft supported in an end wall and attached thereto a support device for filter elements arranged at a distance from the tank axis, the filter elements being fluidically connected to the hollow shaft for discharging a filtered permeate from the tank, wherein an inner lateral surface of the tank comprises at least one guide for diverting the liquid toward the filter elements. At least one of the at least one guide forms a receptacle for at least one conditioning device for adjusting process conditions.

A method of continuous filtration of contaminants from a contaminated viscous fluid, the method may include: pumping the contaminated viscous fluid between a non-perforated surface being a first cylinder and a second perforated surface being a second cylinder disposed substantially parallel to each other at a defined first gap, moving the non-perforated surface and the perforated surface with respect to each other includes one or more longitudinal fins protruding from second cylindrical body into the first gap towards the perforated surface of the first cylindrical body thereby forming a second gap between the distal tips of the fins and the perforated surface, thereby forcing movement of the contaminated viscous fluid in a direction substantially parallel to the relative speed thereby generating a shear rate in the contaminated viscous fluid near the perforated surface in the direction substantially parallel to the relative speed.

A water purification system and method embodying a submerged conduit with a semipermeable surface, thereby leveraging water pressure to cost-effectively and energy-efficiently purify the water that permeates the semipermeable surface. A intake conduit may provide the semipermeable surface, wherein the system contemplates rotating the intake conduit so that as it rotates it engages brushes or blades that clear the semipermeable surface of obstructions.

The present invention relates to a filtration device comprising: at least one enclosure (1; 1A, 1B; 1A, 1B, 1C, 1D) defining a longitudinal axis, said enclosure being obstructed at each end by at least one sealing plate (2A, 2B; 2C, 2D), at least one filtration disc (4) that is rotated and at least one spacer (10) placed between each filtration disc (4), said spacer (10) defining an inter-disc space (10A), at least one hollow rotation shaft (3; 3A) that rotates said at least one filtration disc (4), said shaft having at least one port (33) adapted to collect filtrate (11A, 11B), said filtration disc (4) and said spacer (10) being arranged on said at least one rotation shaft (3; 3A, 3B) inside said enclosure (1; 1A, 1B; 1A, 1B, 1C , 1D), characterised in that said enclosure (1; 1A, 1B; 1A, 1B, 1C, 1D) is passed through by said at least one rotation shaft (3; 3A), and said rotation shaft (3; 3A) is driven by at least one separate rotation means (5, 5A, 5B, 5C) on at least one of the ends of said shaft, said rotation means and said rotation shaft being coaxial, and in that the device comprises at least two separate discharge means (13A, 13B) for the filtrate (11A, 11B), said discharge means being located on said rotation shaft outside said enclosure.

An apparatus for filtration has a feed of sludge, containing liquid, solids and gases fed into a tank, the tank containing at least one spinning separation filter comprising a filter cone set having a filter screen, and a barrier cone, arranged roughly in parallel, and defining a conical workspace between them, the conical workspace having a peripheral opening to the tank and a central opening communicating with the interiors of one or more hollow shafts supporting the barrier cone and the filter cone, the upper shaft supporting the barrier cone having an upper axial channel for the exit of gases, the lower shaft supporting the center of the filter cone having a lower axial channel for the exit of liquid or oil, motor means for producing rotation in said at least one spinning separation filter, and a filtrate liquid reservoir located underneath the filter cone for capturing the filtrate passing through the filter screen.

A dynamic filtration system and method for solid-fluid separation to eliminate or substantially reduce media blinding includes: a fluid inlet through which to receive an inlet flow of fluid to be filtered; a filter membrane; a rotatable mechanical barrier, disposed within an outer shell, to contain the filter membrane and through which to receive and filter the inlet flow of the fluid, the rotatable mechanical barrier configured to rotate dynamically along an axis, to create a high shear flow, thereby to prevent an accumulation of solids on the filter membrane, and whereby a resultant centrifugal force propels any solids and slurry onto the outer shell to be continuously removed from the dynamic filter system; a fluid outlet through which to disperse a filtered fluid; and a solids and slurry outlet through which to disperse solids and slurry collected in filtration when propelled to the outer shell of the mechanical barrier.

The invention relates to a new method of preparation of a polynuclear iron compound stabilized by carbohydrates and/or humic acid or forming a complex with carbohydrates and/or humic acid using a pressure-driven filtration process.