Compositions and methods are described for self-assembled polymer materials having at least one of macro, meso, or micro pores.

A porous membrane comprising stacked layers of nanosheets, each nanosheet comprising one to three atomic layers of a 2D material comprising or consisting of one or more transition metal dichalcogenides is provided. The nanosheets have pores and the membrane comprises a network of water permeation pathways including through-pathways formed by the pores, horizontal pathways formed by gaps between the layers, and vertical pathways formed by gaps between adjacent nanosheets and stacking defects between the layers. Also provided is a method for making the membrane.

Disclosed are methods for coupling a ligand to a composite material. Covalent bonds are formed between functionalized composite materials and ligands as a ligand solution flows through or across the composite materials. The composite materials are useful as chromatographic separation media.

A process for the preparation of a filtration membrane, which includes providing an aqueous suspension of vesicles having transmembrane proteins incorporated therein, the vesicles being formed from an amphiphilic block copolymer having reactive end groups; providing a porous support; functionalizing a surface of the porous support to introduce reactive groups on the surface which are capable of reacting with the reactive end groups of the amphiphilic block copolymers of the vesicles; depositing said suspension of vesicles on a surface of the porous support; and providing reaction conditions such that covalent bonds are formed between the vesicles and the surface.

The present invention generally relates to systems and methods for the separation and removal of carbon dioxide from a liquid, for example, seawater. The systems include an extraction system that collects carbon dioxide from the seawater through a medium, and removes carbon dioxide from the medium; the extraction systems comprising a reactor and a membrane. Alternatively, the extraction system includes a reactor, a membrane and a catalyst.

The invention relates to the providing of hydrophobic and hydrophilic polymer-based hollow fiber membranes containing a water-insoluble antioxidant; in particular, the invention relates to the providing of hollow fiber membranes for the extracorporeal treatment of blood, wherein the hollow fiber membranes have improved biocompatibility relative to treatment blood, in particular improved complement activation and lower platelet loss vis-à-vis treatment blood. At the same time, the elution of hydrophilic polymers from the lumen of the hollow fiber membrane is reduced.

The invention relates to the providing of hydrophobic and hydrophilic polymer-based hollow fiber membranes containing a water-insoluble antioxidant; in particular, the invention relates to the providing of hollow fiber membranes for the extracorporeal treatment of blood, wherein the hollow fiber membranes have improved biocompatibility relative to treatment blood, in particular improved complement activation and lower platelet loss vis-à-vis treatment blood. At the same time, the elution of hydrophilic polymers from the lumen of the hollow fiber membrane is reduced.

Biological filters for removing target components from biological fluids such as removal of pathogenic cells from whole blood, are described. The filters may include a medium comprising an inert surface, with capture material disposed on the inert surface. The filter may be configured to selectively recognize, capture, and remove target cells such as pathogenic cells associated with a disease, such as an autoimmune disease or cancer. Devices, systems, apparatuses, computer readable media, and methods associated with biological filtering are also provided.

The present disclosure relates to a method of preparing a thin film composite layer immobilizing vesicles incorporating a transmembrane protein on a porous substrate membrane, comprising providing an aqueous solution comprising the vesicles and a di-amine or tri-amine compound, covering the surface of a porous support membrane with the aqueous solution, applying a hydrophobic solution comprising an acyl halide compound, and allowing the aqueous solution and the hydrophobic solution to perform an interfacial polymerization reaction to form the thin film composite layer.

Flow capture device and method for removing cells from blood The current invention discloses a blood treating and/or purifying device for removing circulating pathogens, preferably pathogenic cells, more preferably circulating tumor cells from the blood of a patient, a method of producing such a device and method to treat cancer and other diseases caused by virus infection, bacterial infection and parasites infection as well as autoimmune disorders. The described method is an extracorporeal medical therapy, thus can be done also in a hemodialysis system. The current invention also describes a device and an in-situ production method of preparing the device to remove CTC and other pathogens i.e. virus, bacteria or parasites from the bloodstream.