Devices, systems, and their methods of use, for generating droplets are provided. One or more geometric parameters of a microfluidic channel can be selected to generate droplets of a desired and predictable droplet size.

An exhaust gas/reactant mixing arrangement for an exhaust system of an internal combustion engine mixes exhaust gas and reactant. The mixing arrangement includes an exhaust gas guide housing defining a longitudinal axis and having a housing wall. An exhaust gas duct is surrounded by the housing wall and exhaust gas can flow therethrough. A mixing zone has a mixing chamber formed between an upstream end wall and a downstream end wall and a reactant dispensing arrangement is supported on the exhaust gas guide housing. The reactant dispensing arrangement dispenses reactant into the mixing chamber along a reactant dispensing line in a dispensing direction. A mixture flow path leads from an inflow opening to an outflow opening and is formed in the mixing chamber. The mixture flow path has two flow deflection regions, which follow one another in a mixture flow direction and have mutually opposite flow deflection directions.

Disclosed herein is a device (1) for generating a dispersion of a first phase in a second phase, the device comprising a first inlet (2) for supplying a first phase, which opens into a first chamber (4), a second inlet for supplying a second phase, opening into a second chamber and a dispersion outlet (6) for collecting the dispersion. Furthermore, the device comprises a membrane (7), which separates the first chamber (4) and the second chamber (5) and which comprises a first side (8) facing the first chamber (4) and a second side (9) facing the second chamber (5). The membrane (7) comprises multiple channels (10) extending from the first side (8) to the second side (9), providing a fluidic connection between the first chamber (4) and the second chamber (5). Each channel (10) comprises a channel inlet (11) arranged on the first side (8) mid a channel outlet 812) arranged on the second side (9). The first chamber (4) is typically configured such that a flow rate of the first phase through all of the individual channels (10) is essentially equal.

A gas mixer (100), to which a first gas and a second gas are fed, mixes the two fed gases to form a gas mixture. A helical component (2) is arranged in an interior of an outer component (5). A helical mixing cavity (20) is formed between the outer component and the helical component (2). An additional mixing volume (6) is located in the interior of the outer component (5) or in the interior of the helical component (2). One gas is sent through a first feed line (31) to the helical mixing cavity (20), and the other gas is sent through a second feed line (32) to the additional mixing cavity (6). A gas mixture discharge line (40) discharges the produced gas mixture from the helical mixing cavity (20).

Provided herein is a method for preparing microcarrier particles, comprising the steps of allowing the dispersed phase liquid flow through a multi-hole plate at a low temperature to form liquid microspheres in a continuous phase, and enabling a synthetic polymer and/or natural biological macromolecules within the liquid microspheres to be subject to a curing reaction at a low temperature to form particles. Further provided herein are the method for preparing an emulsion and an apparatus and process system for preparing microcarrier particles, which can be used for preparing emulsions and microcarrier particles on a large scale.

An exhaust gas/reactant mixing arrangement for an exhaust system of an internal combustion engine mixes exhaust gas and reactant. The mixing arrangement includes an exhaust gas guide housing defining a longitudinal axis and having a housing wall. An exhaust gas duct is surrounded by the housing wall and exhaust gas can flow therethrough. A mixing zone has a mixing chamber formed between an upstream end wall and a downstream end wall and a reactant dispensing arrangement is supported on the exhaust gas guide housing. The reactant dispensing arrangement dispenses reactant into the mixing chamber along a reactant dispensing line in a dispensing direction. A mixture flow path leads from an inflow opening to an outflow opening and is formed in the mixing chamber. The mixture flow path has two flow deflection regions, which follow one another in a mixture flow direction and have mutually opposite flow deflection directions.

A microfluidic apparatus includes a substrate defining a microchannel having inlet and an outlet defining a length of the microchannel. The microchannel has a main channel extending from the inlet to the outlet, and a plurality of side cavities extending from the main channel. The cavities are in fluid communication with the main channel. A method includes introducing a sample into the microchannel through the inlet to fill the entire microchannel, and then introducing a solvent into the microchannel through the inlet at a controlled flow rate and inlet pressure. A developed solvent front then moves along the main channel from the inlet to the outlet while displacing the sample in the main channel. Images of the microchannel are acquired as the front moves, and a miscibility condition is determined based on the images.

An embodiment for a microfluidic device is provided. The device comprises two areas, arranged side-by-side, and a trigger channel. They include a first area, which is delimited by a first liquid pinning barrier, and a second area, which is delimited by a second liquid pinning barrier. The latter extends parallel to the first liquid pinning barrier to delimit a corridor. The trigger channel extends through the corridor between the two areas. In addition, the trigger channel connects the first liquid pinning barrier with the second liquid pinning barrier, allowing a first liquid pinned at the first liquid pinning barrier and a second liquid pinned at the second liquid pinning barrier to be contacted, each, by a reverse flow of the second liquid in the trigger channel and thereby start mixing at a level of the corridor, in operation. The invention is further directed to related methods of operation.

Devices, systems, and their methods of use, for generating droplets are provided. One or more geometric parameters of a microfluidic channel can be selected to generate droplets of a desired and predictable droplet size.

The mixing nozzle has a throat section, a diffuser section, a gas nozzle section, a first liquid suction port, a liquid nozzle section, a second liquid suction port, a baffle plate, and a jetting port. The first liquid suction port liquidly absorbs the solution in the water storage pool from a side of the gas nozzle section toward the gas nozzle tip. The liquid nozzle section extends to the downstream side of the gas nozzle section with intervening the first liquid suction port. The second liquid suction port liquidly absorbs the solution in the water storage pool from a side of the liquid nozzle section toward the liquid nozzle tip. The baffle plate is provided such that the mixed flow mixed in the diffuser section collides in front of a downstream end of the diffuser section, and divides and reverses the mixed flow.