Acoustofluidic systems including acoustic wave generators for manipulating fluids, droplets, and micro/nano objects within a fluid suspension and related methods are disclosed herein. According to an aspect, an acoustofluidic system includes a substrate including a substrate surface. The system also includes an acoustic wave generator configured to generate acoustic streaming within an acoustic wave region of the substrate surface. Further, the acoustic wave generator is controllable to change the acoustic streaming for movement of a droplet or other micro/nano object on a fluid suspension about the acoustic wave region.

Acoustofluidic systems including acoustic wave generators for manipulating fluids, droplets, and micro/nano objects within a fluid suspension and related methods are disclosed herein. According to an aspect, an acoustofluidic system includes a substrate including a substrate surface. The system also includes an acoustic wave generator configured to generate acoustic streaming within an acoustic wave region of the substrate surface. Further, the acoustic wave generator is controllable to change the acoustic streaming for movement of a droplet or other micro/nano object on a fluid suspension about the acoustic wave region.

The system for making suspensions includes a housing, with a platform mounted therein and a translating table slidably mounted on the platform for removably supporting a receptacle. A base fluid tank stores a base fluid, and a solid particle container stores solid particles. A rotating dispenser system is mounted within the housing, above the platform and the receptacle. The rotating dispenser includes a base fluid dispenser for dispensing a controlled mass of the base fluid into the receptacle, and a solid particle dispenser for dispensing a controlled mass of the solid particles into the receptacle. The base fluid dispenser is in communication with the base fluid tank, and the solid particle dispenser is in communication with the solid particle container. A mixer selectively and controllably mixes the controlled mass of the base fluid and the controlled mass of the solid particles in the receptacle to form the suspension.

The system for making suspensions includes a housing, with a platform mounted therein and a translating table slidably mounted on the platform for removably supporting a receptacle. A base fluid tank stores a base fluid, and a solid particle container stores solid particles. A rotating dispenser system is mounted within the housing, above the platform and the receptacle. The rotating dispenser includes a base fluid dispenser for dispensing a controlled mass of the base fluid into the receptacle, and a solid particle dispenser for dispensing a controlled mass of the solid particles into the receptacle. The base fluid dispenser is in communication with the base fluid tank, and the solid particle dispenser is in communication with the solid particle container. A mixer selectively and controllably mixes the controlled mass of the base fluid and the controlled mass of the solid particles in the receptacle to form the suspension.

A method for generating a stirring in a fluid microdrop, the volume of which is preferably greater than several tens of nanolitres, using an actuator device comprising a high-overtone bulk acoustic resonator HBAR having a quality factor Q of at least 100 in air and including a support which is substantially flat and coated with a layer of dielectric material. The HBAR resonator is associated with a modulatable electronic device capable of generating high-frequency waves. The method envisages depositing, on the support, a fluid microdrop, generating a sinusoidal electrical signal by controlling the modulatable electronic device at a chosen frequency, the frequency being between 100 MHz and 4 GHz, and transformation of the sinusoidal electrical signal having the chosen frequency into high-frequency acoustic waves (OA) by the HBAR resonator.

A method for generating a stirring in a fluid microdrop, the volume of which is preferably greater than several tens of nanolitres, using an actuator device comprising a high-overtone bulk acoustic resonator HBAR having a quality factor Q of at least 100 in air and including a support which is substantially flat and coated with a layer of dielectric material. The HBAR resonator is associated with a modulatable electronic device capable of generating high-frequency waves. The method envisages depositing, on the support, a fluid microdrop, generating a sinusoidal electrical signal by controlling the modulatable electronic device at a chosen frequency, the frequency being between 100 MHz and 4 GHz, and transformation of the sinusoidal electrical signal having the chosen frequency into high-frequency acoustic waves (OA) by the HBAR resonator.

The current invention relates to the method and apparatus to magnetically separate biological entities with magnetic labels from a fluid sample. The claimed magnetic separation device removes biological entities with magnetic labels from its fluidic solution by using a soft-magnetic center pole with two soft-magnetic side poles. The claimed device further includes processes to dissociate entities conglomerate after magnetic separation.

The current invention relates to the method and apparatus to magnetically separate biological entities with magnetic labels from a fluid sample. The claimed magnetic separation device removes biological entities with magnetic labels from its fluidic solution by using a soft-magnetic center pole with two soft-magnetic side poles. The claimed device further includes processes to dissociate entities conglomerate after magnetic separation.

A portable preparation assembly to prepare liquid cosmetic/cleanser products in a personalised way has a container which is configured to contain a solvent liquid and includes a base wall, a lateral wall and an upper opening opposite to the base wall; a housing seat configured to house a solid cosmetic/cleanser and arranged at least partially inside the container; and a stirring device which is configured to stir the solvent liquid in the container so as to determine at least partial dissolution of the solid cosmetic/cleanser in the solvent liquid and mix the dissolved solid cosmetic/cleanser with the solvent liquid to obtain the liquid cosmetic/cleanser product.

A portable preparation assembly to prepare liquid cosmetic/cleanser products in a personalised way has a container which is configured to contain a solvent liquid and includes a base wall, a lateral wall and an upper opening opposite to the base wall; a housing seat configured to house a solid cosmetic/cleanser and arranged at least partially inside the container; and a stirring device which is configured to stir the solvent liquid in the container so as to determine at least partial dissolution of the solid cosmetic/cleanser in the solvent liquid and mix the dissolved solid cosmetic/cleanser with the solvent liquid to obtain the liquid cosmetic/cleanser product.