In one aspect, the invention provides a fluid dispenser comprising a housing configured to receive a means for pressurizing and a disposable fluid bag, and a nozzle towards a distal end. A means for flow control comprising a tubular body whose longitudinal axis coincides with the longitudinal axis of the nozzle having a diameter that tapers from the side distal to the nozzle towards the nozzle is provided. The tubular body is configured to move along its longitudinal axis such that a volume of a gap between the tubular body and the nozzle is varied thus controlling the flow rate. Further, an adapter configured to be fitted onto the nozzle capable of receiving at least one applicator is provided. The fluid dispenser of the invention is capable of being used in a variety of situations in a facile manner, replacing several different devices to be used for individual applications.

The present invention relates to a shaker bottle device that has a body and a lid. The body is further preferably comprised of at least one measuring line that indicates a corresponding amount of liquid or solid volume that is within the body, wherein the line is further highly visible using contrasting colors, fiber-optic, fluorescent, or luminescent paint. The body may also be comprised of a weighted bottom surface that prevents the device from spilling. The body and lid may also have at least one magnet that allows the device to magnetically attach to a metal surface or object to further prevent spilling.

An agitator may include one or more members adjustable between an expanded configuration and a compressed configuration. When the one or more members are in the expanded configuration, the agitator in a first set of two orthogonal dimensions is larger than an opening having a predetermined size. When the one or more members are in the compressed configuration, the agitator in a second set of two orthogonal dimensions is smaller than the opening having the predetermined size. The one or more members are biased to the expanded configuration in absence of external force applied to the one or more members. In use, the agitator may be inserted into a container through a neck of the container in the compressed configuration. The agitator may expand within the container so that the container does not fit through the neck of the container.

The disclosure describes methods and devices with which to process and analyze difficult chemical, biological, environmental samples including but not limited to those containing bulk solids or particulates. The disclosure includes a cartridge which contains a separation tube as well as one or more valves and cavities for receiving raw sample materials and for directing and containing various fluids or samples. The cartridge may contain a separation fluid or density medium of defined density, and structures which direct particulates toward defined regions of the cartridge. Embodiments can include a rotational device for rotating the cartridge at defined rotational rates for defined time intervals. Embodiments allowing multiple assays from a single sample are also disclosed. In some embodiments, this device is used for direct processing and chemical analysis of food, soil, blood, stool, motor oil, semen, and other samples of interest.

Disclosed herein are devices, apparatuses, and methods for grinding of samples. A method includes securing a sample vial in a holder attached to a connecting linkage, the sample vial having a grinding media in the sample vial. The method includes rotating a crank that is operatively coupled to a proximal end of the connecting linkage at a proximal pivot point so that the proximal pivot point undergoes rotational motion. The method includes restricting a distal pivot point of the connecting linkage to a linear path, the distal pivot point near a distal end of the connecting linkage. A result being that the sample vial undergoes a combination of rotational and linear motion.

Provided are methods and devices for dissolving solid protein compositions, such as solid compositions comprising fibrinogen, in an aqueous solvent. The methods comprise use of a closed container containing a volume of solid fibrinogen composition and a head space wherein the pressure within the headspace is sub-atmospheric. Aqueous solvent is introduced into the container while maintain the sub-atmospheric pressure, and subsequent to addition of the solvent, the size of the headspace is decreased to bring the pressure to atmospheric pressure. The devices are suitable for use in the disclosed method.

The disclosure is directed to a sample preparation apparatus for grinding or homogenizing test samples. More specifically, the disclosure relates to grinding samples using rotational and linear motion. Grinding samples can be accomplished with an apparatus with a slider-crank mechanism that is attached to an oscillating connecting linkage. The amplitude of oscillatory motion can be greater than or equal to a length of a sample processing chamber.

Apparatus and method for forming beverages using a beverage cartridge and sonic energy. A cartridge may include a sonic receiver, such as a feature that extends into an interior space of the cartridge and is arranged to receive a sonic emitter that introduces sonic energy into the interior space. The sonic receiver may be excited by sonic energy, which causes the sonic receiver to itself introduce sonic energy into the cartridge.

A concrete comprises in relative parts by weight: 100 of Portland cement; 0.25 to 9 of a defoamer; 0.001 to 6 of a surfactant; 0 to 230 of coarse gravel and/or fine gravel and/or shear enhancers; 0 to 85 of sand; 0 to 60 of a particulate pozzolanic or non-pozzolanic material or a mixture thereof having a mean particle size less than 15 micrometers; 0 to 80 of a particulate pozzolanic or non-pozzolanic material or a mixture thereof having a mean particle size between 15 to 88 micrometers; 0.3 to 18 of a water-reducing superplasticizer; 0 to 14 of polyethylene fibers; and 5 to 40 of water. An air mixing process using a tightly sealed mixing tool is used to thoroughly mix the constituents of the concrete before adding the water for curing. By adjusting relative parts in the composition, concretes of high and ultrahigh performance can be achieved efficiently.

A specimen disrupting apparatus includes: a drive unit that rotates the lower portion of a container having a solution that includes a specimen, a great number of small diameter beads, and a large diameter bead stored therein; and a control unit that controls the drive unit. The control unit controls the drive unit such that the lower portion of the container rotates at two or more different rotational speeds which are changed continuously.