A method of mixing a pharmaceutical solution including adding a gas into an interior compartment of a mix bag to form a headspace. The interior compartment of the mix bag includes a top portion and a bottom portion. The headspace adjacent to the top portion contains gas. The method includes adding a solvent into the mix bag, and establishing a bubble column in the interior compartment by activating a recirculation assembly. The recirculation assembly includes a connecting pathway operably coupled to a recirculation pump. A first end of the connecting pathway is coupled to a top gas recirculation port and a second end is coupled to a bottom gas recirculation port of the mix bag such that the recirculation pump draws the gas from the headspace and delivers the gas to the interior compartment via the bottom gas recirculation port. The method includes adding a solute into the mix bag.

Disclosed are a stirring process and a stirring system for a neodymium-iron-boron powder and a process for manufacturing a neodymium-iron-boron magnetic steel. The stirring process for the neodymium-iron-boron powder mainly comprises the following aeration, feeding and stirring. Specifically, the aeration refers to filling a mixer with nitrogen and/or an inert gas, with the internal space of the mixer closed; the feeding refers to placing a neodymium-iron-boron powder to be stirred into the mixer and keeping the internal space of the mixer closed; and the stirring refers to introducing the mixer with a pulsed air stream, which is an intermittently jetted air stream formed by nitrogen and/or an inert gas, and by which the neodymium-iron-boron powder can be repeatedly blown up and down to mix and stir the neodymium-iron-boron powder.

A diagnostic system for determining the presence of a target in a sample liquid that includes a diagnostic reader and a microfluidic strip having a microfluidic channel network therein. An actuator within the reader modifies the pressure of a gas in gaseous communication with a liquid-gas interface of a sample liquid within the microfluidic channel network to move and/or mix the sample liquid. The pressure modifications may be continuous and/or oscillatory.

A sample introduction system provides mixing of a sample and a diluent within the container via gas injection. In one or more implementations, the sample introduction system causes a probe of an autosampler to be inserted into a container containing a sample and a diluent so that an end of the probe is submerged beneath a surface of the diluent and the sample. Gas is then injected through the probe to mix the sample and the diluent within the container. An aliquot of the mixed sample and diluent is then withdrawn through the probe.

A system for oxygenating a biological culture includes a container bounding a compartment and having a top wall, a bottom wall, and an encircling sidewall extending therebetween; a tubular member projecting into the compartment of the container and terminating at a terminal end; a gas supply coupled with the tubular member and being configured to blow gas through the tubular member; and a mixing element disposed within compartment of the container at a location between the terminal end of the tubular member and the bottom wall of the container, the mixing element being configured to mix the liquid.

A microsphere cavity that forms a whispering gallery mode is used. By vibrationally coupling a whispering gallery mode being one of kinds of an optical mode to a vibrational mode of water or a liquid other than water, ultra strong coupling water or a liquid in a vibrational coupling state is generated. A first example is to acquire aerosol in which water itself or a liquid itself other than water constitutes a micro-water sphere cavity or a micro-liquid sphere cavity (50) and is a dispersoid. A second example is to acquire colloid or emulsion in which a micro-dielectric sphere cavity (53) is a dispersoid and water or a liquid other than water is a dispersion medium.

Some variations provide a system for producing a functionalized powder, comprising: an agitated pressure vessel; first particles and second particles contained within the agitated pressure vessel; a fluid contained within the agitated pressure vessel; an exhaust line for releasing the fluid from the agitated pressure vessel; and a means for recovering a functionalized powder containing the second particles disposed onto surfaces of the first particles. A preferred fluid is carbon dioxide in liquefied or supercritical form. The carbon dioxide may be initially loaded into the pressure vessel as solid carbon dioxide. The pressure vessel may be batch or continuous and is operated under reaction conditions to functionalize the first particles with the second particles, thereby producing a functionalized powder, such as nanofunctionalized metal particles in which nanoparticles act as grain refiners for a component ultimately produced from the nanofunctionalized metal particles. Methods for making the functionalized powder are also disclosed.

A system for performing a gas-liquid mass transfer includes a container bounding a compartment and having a top wall, a bottom wall, and an encircling sidewall extending therebetween. A tube has a first end and an opposing second end, the first end of the tube being disposed within the compartment of the container. A nozzle is disposed within the compartment of the container and has at least one outlet, the nozzle being coupled with the tube so that a gas can be passed through the tube and out the at least one outlet of the nozzle. The nozzle is sufficiently buoyant so that when a fluid is disposed within the compartment of the container, the nozzle floats on the fluid.

A sample introduction system provides mixing of a sample and a diluent within the container via gas injection. In one or more implementations, the sample introduction system causes a probe of an autosampler to be inserted into a container containing a sample and a diluent so that an end of the probe is submerged beneath a surface of the diluent and the sample. Gas is then injected through the probe to mix the sample and the diluent within the container. An aliquot of the mixed sample and diluent is then withdrawn through the probe.

The present invention provides method for separating contaminants from a liquid mixture comprising the steps of a) providing a feed of said liquid mixture to be purified, b) adding a separation aid to the liquid mixture to be purified, wherein said separation aid is capable of binding said contaminants and c) supplying a flow of compressed air into said feed after step b) has been performed to provide a feed comprising air. The method further comprises steps d) removing air from said feed comprising air to provide a deaerated feed; and e) supplying said deaerated feed to a separator, and f) separating a phase comprising contaminants and said separation aid from said liquid mixture in said separator, wherein the separation aid added in step b) is insoluble in said liquid mixture at the separation conditions in step f). The present invention further provides a system for separating contaminants from a liquid mixture.