An insert assembly for a foam generating device includes a first insert and a second insert with a channel defined therethrough. Inserts may be formed by two shell halves that are coupleable to one another to define the channel. A plurality of ribs extends along an interior surface of the channel. Pad structures defined by porous media are provided in the channel and gripped by the plurality of ribs. The pads receive cleaning solution passing through the channel and cause foam to be generated by breaking-up the cleaning solution and agitating. The ribs may be arranged horizontally relative to a longitudinal axis of the insert assembly and retain the pads within the device. Inserts may be arranged in series along a longitudinal axis of the foam generating device with the pad structures arranged within the channel.

A homogenous mixing apparatus comprises: a circulation unit, a dynamic mixing unit, wherein a feeding port of the first-stage dynamic mixing device communicates with the discharging end of the circulation unit, a discharging port of the third-stage dynamic mixing device communicates with the feeding end of the circulation unit, and each of the dynamic mixing devices comprises a dynamic mixer; and a control unit, configured to be capable of controlling the dynamic mixing unit, so that the dynamic mixers of the first-stage, the second-stage dynamic mixing device, and the third-stage dynamic mixing device are capable of being independently started and shut down and operated at independent rotating speeds, wherein the dynamic mixers each comprise a stator and a rotor, rotating speed ranges of the dynamic mixers of the first-stage, second-stage, and third-stage dynamic mixing device increase in sequence, and distances between the rotors and the stators decrease in sequence.

A first solution is mixed and diluted with diluting liquid to make a first dilute solution, a second solution is mixed and diluted with diluting liquid to make a second dilute solution, and the first dilute solution and second dilute solution, both diluted with diluting liquid, are mixed in a sealed tank.

The invention relates to an apparatus for aerating a pasty product. The apparatus comprises a housing (1) with an inlet (4) for the pasty product to be aerated and an outlet (5) for the aerated product.

The apparatus comprises at least a first set of a rotor and a stator (21) and a second set of a rotor and a stator (22). The apparatus further comprises a gas injector (6) for injecting, upstream of the first set of a rotor and a stator (21), a gas into the pasty product to be aerated.

The apparatus further comprises an intermediate mixing chamber (7) provided in the housing between the first and the second sets of a rotor and a stator (21,22). A secondary product introduction means protrudes into the intermediate mixing chamber (7) so as to issue into said intermediate mixing chamber (7).

A method for aerating a pasty product is also provided.

An apparatus, vortex generator assembly and method for automated cell lysis and nucleic acid purification and processing. The vortex generator assembly includes sample holder having a lysis well, at least one wash well, and an elution well. The vortex generator assembly also includes a sample holder cover having a plurality of vibration rods for creating a vortex in the wells of the sample holder. The apparatus includes motor operating a rotating cam to cause the vibration rods to vibrate and create the vortex in a well holding fluid and magnetic beads, wherein the vortexing speed is sufficient to overcome the magnetic attraction between the beads and disperse the beads in solution, to collect nucleic acids such as DNA.

A static mixer (100), comprising a static mixer housing, having an inlet port (120) for receiving a fluid, a channel (104) in fluid communication with the inlet port (120), a raised rib along a perimeter of the channel (104), a flow splitter for splitting the fluid into a first stream (106a) and a second stream (106b) within channels, a second flow splitter for splitting the first stream (106a) into a third stream (110a) and a fourth stream (110b) within channels and a third flow splitter for splitting the second stream (106b) into a fifth stream (110c) and a sixth stream (110d) within channels, a first T-style junction for rejoining and mixing the third stream and the fourth stream within a channel (112a), a second T-style junction for rejoining and mixing the fifth stream and the sixth stream within a channel (112b), and a third T-style junction for rejoining and mixing the streams; and a plastic film, the plastic film sealed to the raised rib, forming a static mixer (100) capable of mixing the fluid while remaining in a state of laminar flow.

Apparatus for mixing polymer, the apparatus comprising (i) a mixer housing including an internal chamber, said internal chamber having first and second sections in fluid communication with each other through a passageway; (ii) a first ram received in said first section; and (iii) a second ram received in said second section, where the apparatus is adapted to receive a composition including polymer within said internal chamber and move said composition between said first and second chambers through said passageway by operation of said first and second rams.

The present disclosure provides methods and compositions for detecting polynucleotides in a sample and for quantifying polynucleotide load in a sample. The polynucleotides can be associated with a disease, disorder, or condition. In some applications, methylated DNA is quantified, e.g., in order to determine the load of polynucleotides in a sample. The present disclosure also provides methods and compositions for determining the load of fetal polynucleotides in a biological sample, e.g., the load of fetal polynucleotides (e.g., DNA, RNA) in maternal plasma. The present disclosure provides methods and compositions for detecting cellular processes such as cellular viability, growth rates, and infection rates. This disclosure also provides compositions and methods for detecting differences in copy number of a target polynucleotide. In some embodiments, the methods and compositions provided herein are useful for diagnosis of fetal genetic abnormalities, when the starting sample is maternal tissue (e.g., blood, plasma). The methods and materials described apply techniques for allowing detection of small, but statistically significant, differences in polynucleotide copy number.

This invention provides compositions and methods for detecting differences in copy number of a target polynucleotide. In some cases, the methods and compositions provided herein are useful for diagnosis of fetal genetic abnormalities, when the starting sample is maternal tissue (e.g., blood, plasma). The methods and materials described apply techniques for allowing detection of small, but statistically significant, differences in polynucleotide copy number.

An apparatus includes a housing with an inlet for a pasty product to be aerated and an outlet for the aerated product. The apparatus includes at least a first set of a rotor and a stator and a second set of a rotor and a stator. The apparatus further includes a gas injector for injecting, upstream of the first set of the rotor and the stator, a gas into the pasty product to be aerated. The apparatus further includes an intermediate mixing chamber provided in the housing between the first and the second sets of the rotor and the stator . A secondary product introduction member protrudes into the intermediate mixing chamber so as to issue into the intermediate mixing chamber. A method for aerating a pasty product is also provided.