The present invention relates to a method for preparation of monodisperse cell-targeting giant unilamellar vesicles based on symmetrically division of a parent polymer shell-stabilized giant unilamellar vesicle into smaller polymer shell-stabilized giant unilamellar vesicles with a diameter between 1 μm and 10 μm using a microfluidic splitting device. The inventive method allows preparation of differently charged giant unilamellar vesicles as well as bioligand- and PEG-conjugated giant unilamellar vesicles, which are useful for targeted cellular delivery at high efficiency and specificity. A further advantage of the present invention is that the giant unilamellar vesicles can deliver huge cargos such as drug releasing porous microparticles, high amounts of in vivo imaging probes, viruses, or up-and-coming DNA origami robots.

This invention refers to a paint composition with prolonged release biocides to repel, reduce, and control insects, characterized by: a) A cbp vehicle, preferably a water-based acrylic vinyl paint; b) At least one pyrethroid biocide or its mixture, selected from: b1) microencapsulated deltamethrin as an active ingredient: b2) microencapsulated cypermethrin as an active ingredient; Where said pyrethroid biocides are activated or catalyzed through (PBO) piperonyl butoxide, and Wherein said microcapsules of the active ingredients are obtained through a microencapsulation process by interfacial polymerization, and/or a microencapsulation by ionic gelation process, for a prolonged release with regards to the biocidal active ingredients' interval.

To provide a quantum dot and manufacturing method of the dot particularly capable of reducing organic residues adhering to the quantum dot surface and of suppressing the black discoloration occurrence of a layer including the quantum dot positioned immediately above a light emitting device, and a compact, sheet member, wavelength conversion member and light emitting apparatus with high luminous efficiency using the quantum dot, a quantum dot of the present invention has a core portion including a semiconductor particle, and a shell portion with which the surface of the core portion is coated, and is characterized in that a weight reduction up to 490° C. is within 75% in a TG-DTA profile. Further, the quantum dot of the invention is characterized in that oleylamine (OLA) is not observed in GC-MS qualitative analysis at 350° C.

To provide a quantum dot and manufacturing method of the dot particularly capable of reducing organic residues adhering to the quantum dot surface and of suppressing the black discoloration occurrence of a layer including the quantum dot positioned immediately above a light emitting device, and a compact, sheet member, wavelength conversion member and light emitting apparatus with high luminous efficiency using the quantum dot, a quantum dot of the present invention has a core portion including a semiconductor particle, and a shell portion with which the surface of the core portion is coated, and is characterized in that a weight reduction up to 490° C. is within 75% in a TG-DTA profile. Further, the quantum dot of the invention is characterized in that oleylamine (OLA) is not observed in GC-MS qualitative analysis at 350° C.

An object of the present invention is to provide a ferrite particle having a low apparent density, filling a specified volume with a low weight with various properties maintained in a controllable state, a ferrite carrier core material composed of the ferrite particle, and a ferrite carrier using the ferrite core material and an electrophotographic developer. To achieve the object, the ferrite particle having the outer shell structure containing the Ti oxide for the ferrite carrier core material, and the ferrite carrier using the ferrite particle as the ferrite carrier core material and the electrophotographic developer are employed.

Provided are hollow particles which are more excellent in heat resistance and dispersibility than ever before and which are lightweight. The hollow particles containing hollow resin particles having a surface covered with inorganic fine particles, wherein a volume average particle diameter of the hollow particles is from 0.1 μm to 9.0 μm, and a void ratio thereof is from 55% to 95%; wherein a repeating unit constituting the resin of the hollow resin particles contains a crosslinkable monomer unit, and a content of the crosslinkable monomer unit is from 25 to 100 parts by mass, with respect to 100 parts by mass of the resin; wherein a primary particle diameter of the inorganic fine particles is from 10 nm to 120 nm; and wherein the inorganic fine particles are contained at from 5 to 180 parts by mass, with respect to 100 parts by mass of the hollow resin particles.

Provided are hollow particles which are more excellent in heat resistance and dispersibility than ever before and which are lightweight. The hollow particles containing hollow resin particles having a surface covered with inorganic fine particles, wherein a volume average particle diameter of the hollow particles is from 0.1 μm to 9.0 μm, and a void ratio thereof is from 55% to 95%; wherein a repeating unit constituting the resin of the hollow resin particles contains a crosslinkable monomer unit, and a content of the crosslinkable monomer unit is from 25 to 100 parts by mass, with respect to 100 parts by mass of the resin; wherein a primary particle diameter of the inorganic fine particles is from 10 nm to 120 nm; and wherein the inorganic fine particles are contained at from 5 to 180 parts by mass, with respect to 100 parts by mass of the hollow resin particles.

The disclosure relates to a gas-filled microbubble, comprising: a shell encapsulating a gas volume; wherein the shell comprises a gas impermeable molecular layer; wherein the shell is functionalized with a plurality of polymerizable molecules, wherein the polymerizable molecules comprise pentacosadienoic acid, PCDA, derivatives, in particular polyethylene glycol PCDA, PCDA-PEG; wherein the polymerizable molecules are configured to undergo polymerization when being irradiated with UV radiation in a determined wavelength range; and wherein the polymerization of the polymerizable molecules changes physicochemical properties, such as viscoelastic properties, of the microbubble.

The disclosure relates to a gas-filled microbubble, comprising: a shell encapsulating a gas volume; wherein the shell comprises a gas impermeable molecular layer; wherein the shell is functionalized with a plurality of polymerizable molecules, wherein the polymerizable molecules comprise pentacosadienoic acid, PCDA, derivatives, in particular polyethylene glycol PCDA, PCDA-PEG; wherein the polymerizable molecules are configured to undergo polymerization when being irradiated with UV radiation in a determined wavelength range; and wherein the polymerization of the polymerizable molecules changes physicochemical properties, such as viscoelastic properties, of the microbubble.

The present invention relates to a process for producing a particle dispersion comprising the steps of: a) providing a dispersion consisting of a solvent and solid core particles, b) providing a solution of a soluble, interfacially-active polymer having a molecular weight of more than 5 kDa, c) mixing said dispersion of solid core particles with said polymer solution, d) removing free polymer from the obtained mixture; wherein in step a) the solvent is selected from an organic solvent, a mixture of at least two organic solvents or a mixture of at least one organic solvent with water; wherein in step c), the amount of the soluble, interfacially-active polymer mixed with said dispersion of solid core particles exceeds the amount of polymer required to coat the surface of each of the solid core particles with a monolayer of the polymer; wherein step d) is repeated until the requirement described by the following formula is fulfilled:

(ST.sub.disp−18 mN/m)/(ST.sub.solv−18 mN/m)>0.90,

with ST.sub.disp being the surface tension of the modified particle dispersion in [mN/m] and ST.sub.solv being the surface tension of the pure solvent or solvent mixture in [mN/m]; and wherein the solvent or solvent mixture contained in the dispersion of solid core particles is miscible with the solvent or solvent mixture contained in the polymer solution. The present invention also relates to a particle dispersion exhibiting a homogenous drying pattern as well as a film made thereof and the use of the non-aqueous particle dispersion.