The present invention provides a system for the production of a radiopharmaceutical including a radiosynthesis apparatus and a disposable cassette. The system of the invention includes a device that enables a position on the cassette to be freed for inclusion of an additional reagent vial. With the system of the invention a broader range of radiochemical syntheses can be envisaged using the cassette.

The present invention relates to an automated radiosynthesis device adapted for the addition of multiple additional components. The automated radiosynthesis device of the invention enables a wider range of radiochemical synthetic processes to be carried out in an automated fashion.

Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients, are provided. Certain of the systems and methods described herein are capable of manufacturing multiple chemical products without the need to fluidically connect or disconnect unit operations when switching from one making chemical product to making another chemical product.

The present invention provides a method for the synthesis of an injectable composition comprising a [.sup.18F]-labelled pyridaben derivative that is advantageous over prior methods. In particular, the method of the present invention comprises a method of radiosynthesis that permits a more facile purification using solid phase extraction (SPE).

A source vessel weight monitoring assembly for use in reactor systems to provide real-time and direct measurements of the availability of source or process materials from a source vessel. The assembly includes one or more force or load sensors, such as load cells, positioned between a bottom wall of the source vessel and a support element for the vessel (e.g., a base of a source vessel enclosure). The sensors are positioned to at least partially support the vessel, and a signal conditioning element processes the output electrical signals from the sensors, then a controller processes the output signals from the signal conditioning components with a conversion factor, for example, to determine a current weight of the source vessel and process material (e.g., solid, liquid, or gaseous precursor) stored therein. The controller uses this weight to calculate the amount of available process material or chemistry in the source vessel.

A method can be employed to regulate and stably operate a steam reforming system that is operated by steam reforming, that has a capacity utilization level that can be regulated, and that comprises a steam reformer, a hydrogenating and desulfurizing unit that is positioned upstream of the steam reformer and is configured for feedstock desulfurization, and a firing unit of the steam reformer. According to the method, a mandated capacity utilization level for the steam reforming system is established with automated regulation of the following continuously monitored parameter ratios: a hydrogen-to-feedstock ratio in the hydrogenating and desulfurizing unit, a steam-to-carbon ratio in the steam reformer, and a fuel-to-air ratio in the firing unit of the steam reformer.

Disclosed herein are cell processing systems, devices, and methods thereof. A system for cell processing may comprise a plurality of instruments each independently configured to perform one or more cell processing operations upon a cartridge, and a robot capable of moving the cartridge between each of the plurality of instruments.

A method and apparatus for monitoring and evaluation of a production of a functional material, wherein an assessment of steps taken by users based on a data basis results in reporting to the user of the extent to which predetermined properties of a functional material produced are attained in the event of variances in the steps taken.

Disclosed herein are systems, methods and devices for the continuous production and processing of compounds, including biopharmaceutical compounds. The system and devices are operated in an automated manner and capable of operation under Good Manufacturing Practice (GMP)-compliant conditions.

Fuel production system includes: synthesis gas generation unit configured to generate synthesis gas containing hydrogen and carbon monoxide from carbon-containing raw material; fuel production unit configured to produce fuel from synthesis gas generated; water electrolyzer configured to electrolyze water to generate water-electrolyzed hydrogen; hydrogen supply unit configured to supply water-electrolyzed hydrogen generated to synthesis gas generation unit; and controller. The controller is configured to perform: calculating input energy based on first energy possessed by raw material, second energy consumed by water electrolyzer, third energy consumed by synthesis gas generation unit, and fourth energy consumed by fuel production unit; calculating recovered energy based on fifth energy possessed by fuel produced; and controlling water electrolyzer based on input energy and recovered energy calculated.