This invention relates to a new stationary phase carrying functional groups comprising a halogen substituted aromatic ring. Target molecules can interact with this stationary phase by halogen bonding. The stationary phase is suitable for SPE or chromatographic separations.

Described herein is a functional graphene composition comprising a graphene scaffold and one or more metal chelating functional groups covalently bonded to the graphene scaffold and a porous substrate that includes the functional graphene composition. Also provided is a method of removing dissolved metals from an aqueous liquid, such as, acid mine drainage.

The invention relates to strong hydrogen-bond acidic sorbents. The sorbents may be provided in a form that limits or eliminates intramolecular bonding of the hydrogen-bond acidic site between neighboring sorbent molecules, for example, by providing steric groups adjacent to the hydrogen-bond acidic site. The hydrogen bond site may be a phenolic structure based on a bisphenol architecture. The sorbents of the invention may be used in methods for trapping or detecting hazardous chemicals or explosives.

The invention relates to an affinity resin functionalized with small molecule inhibitors of glycoside-cleaving enzymes, e.g., α-galactosidase A (α-Gal A), glucocerebrosidase (GCB), β-galactosidase, and acid alpha-glucosidase (GAA), and a method for purifying glycoside-cleaving enzymes produced in a cell line using the small molecule inhibitor-functionalized affinity resin.

The invention discloses a separation matrix comprising a plurality of multimodal ligands covalently coupled to a support, wherein said support is a membrane comprising nonwoven polymer fibers and wherein said ligands are capable of interacting with a target biomacromolecule. Further, the invention discloses separation methods using the separation matrix.

A filter is treated with a reduced amount of a halo active aromatic sulfanomide compound of Formula (I):

##STR00001##

wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, and R.sub.5 are independently selected from hydrogen, COOR′, CON(R″).sub.2, alkoxy, CN, NO.sub.2, SO.sub.3R″, halogen, substituted or unsubstituted phenyl, sulfonamide, halosulfonamide, and substituted or unsubstituted C.sub.1-C.sub.12 alkyl; R′ is hydrogen, an alkali metal, an alkaline earth metal, substituted C.sub.1-C.sub.12 alkyl, or unsubstituted C.sub.1-C.sub.12 alkyl; and R″ is hydrogen or substituted or unsubstituted C.sub.1-C.sub.12 alkyl, where the two R″ groups in CON(R″).sub.2 may be independently selected; X is halogen; M is an alkali or alkaline earth metal; and n is the number of water molecules per molecule of the sulfonamide compound. The compound effectively suppresses odors pre-use, in use, and post-use for extended periods of time.

Chromatography resins having mixed mode ligands and methods of using such resins are provided.

The disclosure provides a capture system and methods for isolating cysteine-containing peptides from biological fluid and proteolytic mixtures. The disclosure also provides compounds of formulae (II), (III), and (IV), useful in methods of the invention. ##STR00001##

An article that can be used for biomaterial capture comprises (a) a porous substrate; and (b) borne on the porous substrate, a polymer comprising interpolymerized units of at least one monomer consisting of (1) at least one monovalent ethylenically unsaturated group, (2) at least one monovalent ligand functional group selected from acidic groups, basic groups other than guanidino, and salts thereof, and (3) a multivalent spacer group that is directly bonded to the monovalent groups so as to link at least one ethylenically unsaturated group and at least one ligand functional group by a chain of at least six catenated atoms.

An oxygen absorbing agent composition including at least one type of a compound having an indane skeleton represented by the following general formula (1) and a transition metal catalyst: ##STR00001##