An apparatus and a method are used for investigating the naphtha reforming process in catalyst test devices with reactors arranged in parallel. The apparatus has a plurality of reactors arranged in parallel with reaction chambers (R1, R2, . . . ), a product fluid supply, a process control, and at least one analysis unit. Each individual reactor has an outlet line for the product fluid stream, wherein the analysis unit is operatively connected to each outlet line for the product fluid stream and the apparatus is functionally connected to the control of the apparatus. In carrying out the method, naphtha-containing reactant fluid streams are brought into contact with catalysts in the individual reactors and the product fluid streams are subsequently supplied to the online analysis unit from the respective outlet lines of the individual reactors and analyzed. Using the evaluation of the online analytical characterization data, the process parameters of the respective reactor unit are adapted. The process steps of analytical characterization, evaluation, and adaptation of process parameters are repeated for the duration of the investigation.

A catalytic reaction analysis dual reactor system and a method for measuring the catalytic activity of a catalyst by correcting for non-catalytic effects with the catalytic reaction analysis dual reactor system. The dual reactor system contains a first reactor comprising a first catalyst on a first catalyst support, and a second reactor comprising a second catalyst support, wherein the particle size and amount of the first catalyst and the second catalyst support are substantially the same, and the effect of the catalyst is isolated by correcting the result obtained from the first reactor containing the catalyst with the result obtained from the second reactor containing the catalyst support.

A synthesis device comprises a reaction vessel configured to contain a number of carriers and to which a solution is configured to be supplied, and a gas supplier configured to supply a gas to the reaction vessel to stir the solution and the carriers.

The present invention generally relates to droplet libraries and to systems and methods for the formation of libraries of droplets. The present invention also relates to methods utilizing these droplet libraries in various biological, chemical, or diagnostic assays.

A microfluidic device for analysing nucleic acids includes a pump unit with a pumping volume, a filter unit for receiving a lysate, and a reaction chamber. The pump unit, the filter unit and the reaction chamber are arranged in the stated order in a pump direction of the pump unit. The microfluidic device is configured to pump an elution medium via the pump unit into the filter unit for elution and subsequently into the reaction chamber for further treatment.

A microfluidic device comprising a plurality of microreactors is provided. Each microreactor includes at least a first inlet and a second inlet for supplying a first fluid and a second fluid, respectively, to said microreactor and at least one waste channel for draining fluid from said microreactor. The device further comprises a shared first microfluidic supply system for supplying a first fluid to the first inlets of the plurality of microreactors, a shared second microfluidic supply system for supplying a second fluid to the second inlets of the plurality of microreactors. At least one of said inlets to each microreactor comprises at least one valve-less fluidic resistance element having a fluidic resistance that is substantially larger than the fluidic resistance of the corresponding shared microfluidic supply system. A chemical reaction sequencer apparatus including the microfluidic device and a method for supplying reagents to a plurality of microreactors are also provided.

The present invention generally relates to droplet libraries and to systems and methods for the formation of libraries of droplets. The present invention also relates to methods utilizing these droplet libraries in various biological, chemical, or diagnostic assays.

The invention relates to a device for synthesising oligonucleotides, comprising: a reagent container receptacle (1) for holding a reagent container support (17) comprising multiple reagent containers (18); an exchangeable microfluid chip (10) comprising a synthesis chamber, fluid connectors and microfluid valves; a control device (5); fluid connecting means (2); wherein the device can be loaded with the microfluid chip (10) and the reagent container support (17) when in a loading position; a chip receptacle (3). To allow cost-effective and prompt synthesis even of small amounts of oligonucleotides, the invention provides for an actuator device (6) to be provided, with which the reagent container receptacle (1), the microfluid chip (10) and the fluid connecting means (2) can be brought from the loading position to an operating position, in which operating position the reagent container receptacle (1), the chip receptacle (3) and the fluid connecting means (2) are positioned relative to each other such that reagents can be conveyed out of the reagent containers (18) towards the synthesis chamber (14) depending on the valve position of the microfluid valves.

Apparatuses and a method for plate-based oligonucleotide synthesis are disclosed. In one example, an apparatus used in oligonucleotide synthesis includes a machined block to receive a commercially-available synthesis plate. A keeper is used to apply pressure to the commercially-available synthesis plate, and a sealing element is used to seal the commercially-available synthesis plate to the machined block. Other methods and apparatuses are disclosed.

An example method includes reacting a first solution and a different, second solution on a flow cell by flowing the first solution over amplification sites on the flow cell and subsequently flowing the second solution over the amplification sites. The first solution includes target nucleic acids and a first reagent mixture that comprises nucleoside triphosphates and replication enzymes. The target nucleic acids in the first solution transport to and bind to the amplification sites at a transport rate. The first reagent mixture amplifies the target nucleic acids that are bound to the amplification sites to produce clonal populations of amplicons originating from corresponding target nucleic acids. The amplicons are produced at an amplification rate that exceeds the transport rate. The second solution includes a second reagent mixture and lacks the target nucleic acids. The second solution is to increase a number of the amplicons at the amplification sites.