A method for purifying a nonaqueous liquid substance includes: filling a cartridge container with a macroporous or porous type ion exchange resin in a water-wet state to obtain an ion exchange resin-filled cartridge filled with the macroporous or porous type ion exchange resin before water content reduction; reducing a water content of the macroporous or porous type ion exchange resin in the cartridge container until a water content (A) of the macroporous or porous type ion exchange resin after water content reduction becomes 90 to 97% of a water content (B) of the macroporous or porous type ion exchange resin in a saturated equilibrium state; an initial blowing step of allowing the nonaqueous liquid substance before being purified to pass inside the cartridge container filled with the macroporous or porous type ion exchange resin after water content reduction and discharging an initial blow effluent from inside the cartridge container; and purification.

A method for purifying a nonaqueous liquid substance includes: filling a cartridge container with a macroporous or porous type ion exchange resin in a water-wet state to obtain an ion exchange resin-filled cartridge filled with the macroporous or porous type ion exchange resin before water content reduction; reducing a water content of the macroporous or porous type ion exchange resin in the cartridge container until a water content (A) of the macroporous or porous type ion exchange resin after water content reduction becomes 90 to 97% of a water content (B) of the macroporous or porous type ion exchange resin in a saturated equilibrium state; an initial blowing step of allowing the nonaqueous liquid substance before being purified to pass inside the cartridge container filled with the macroporous or porous type ion exchange resin after water content reduction and discharging an initial blow effluent from inside the cartridge container; and purification.

An ion exchange resin bag 5 includes a bag body 51 and a reinforcing body 52. The bag body 51 has a bottom surface portion 511 that is provided at an end portion opposite to an end portion where an opening is provided and forms a bottom surface of the bag body, and a side surface portion 512 that is connected to the bottom surface portion 511 and forms a side surface of the bag body 51. The reinforcing body 52 has a first reinforcing portion 521 that is fixed to a boundary portion of the bottom surface portion 511 and the side surface portion 512, and a second reinforcing portion 522 that is connected to the first reinforcing portion 521 and fixed to at least a part of the side surface portion 512 and extends from the first reinforcing portion 521 toward the opening.

An ion exchange resin bag 5 includes a bag body 51 and a reinforcing body 52. The bag body 51 has a bottom surface portion 511 that is provided at an end portion opposite to an end portion where an opening is provided and forms a bottom surface of the bag body, and a side surface portion 512 that is connected to the bottom surface portion 511 and forms a side surface of the bag body 51. The reinforcing body 52 has a first reinforcing portion 521 that is fixed to a boundary portion of the bottom surface portion 511 and the side surface portion 512, and a second reinforcing portion 522 that is connected to the first reinforcing portion 521 and fixed to at least a part of the side surface portion 512 and extends from the first reinforcing portion 521 toward the opening.

Provided is an process for the automated synthesis of at least one chemical compound including providing at least one substrate in at least one solvent in the at least one reaction container; automatically passing the at least one substrate through at least one first compartment of the at least one cartridge once or several times and collecting a formed substrate-reagent intermediate product in the at least one reaction container prior to passing the substrate-reagent intermediate product into a subsequent compartment; automatically passing the substrate-reagent intermediate product through at least one second compartment once or several times and collecting a formed reaction product prior to passing the reaction product into a subsequent compartment; automatically passing the reaction product through at least one third compartment for purifying the product once or several times and collecting a purified product in the at least one reaction container.

Provided is an process for the automated synthesis of at least one chemical compound including providing at least one substrate in at least one solvent in the at least one reaction container; automatically passing the at least one substrate through at least one first compartment of the at least one cartridge once or several times and collecting a formed substrate-reagent intermediate product in the at least one reaction container prior to passing the substrate-reagent intermediate product into a subsequent compartment; automatically passing the substrate-reagent intermediate product through at least one second compartment once or several times and collecting a formed reaction product prior to passing the reaction product into a subsequent compartment; automatically passing the reaction product through at least one third compartment for purifying the product once or several times and collecting a purified product in the at least one reaction container.

An ion exchanger includes a housing and a cartridge. The housing has an inlet port, through which coolant flows in, and an outlet port, through which the coolant flows out. The cartridge is detachably attached to the housing. The cartridge is filled with ion-exchange resin. The ion exchanger is configured to remove ions from the coolant through ion exchange when the coolant flowing in the housing passes through the ion-exchange resin. The cartridge includes a bypass route that causes some of the coolant that has flowed into the housing to bypass the ion-exchange resin and flow to the outlet port.

An ion exchanger includes a housing and a cartridge. The housing has an inlet port, through which coolant flows in, and an outlet port, through which the coolant flows out. The cartridge is detachably attached to the housing. The cartridge is filled with ion-exchange resin. The ion exchanger is configured to remove ions from the coolant through ion exchange when the coolant flowing in the housing passes through the ion-exchange resin. The cartridge includes a bypass route that causes some of the coolant that has flowed into the housing to bypass the ion-exchange resin and flow to the outlet port.

Methods, sorbent cartridges and cleaning devices are disclosed for refurbishing sorbent materials. In one implementation among multiple implementations, a medical fluid delivery method includes: providing a sorbent cartridge including H.sup.+ZP within a casing for a treatment; and after the treatment, refurbishing the H.sup.+ZP while maintained within the casing via (i) regenerating the non-disinfected H.sup.+ZP by flowing an acid solution through the casing, (ii) rinsing the regenerated H.sup.+ZP while maintained within the casing, (iii) disinfecting the regenerated and rinsed H.sup.+ZP by flowing a disinfecting agent through the casing, and (iv) rinsing the regenerated and disinfected H.sup.+ZP while maintained within the casing. Multiple batch sorbent refurbishing implementations are also disclosed.

Methods, sorbent cartridges and cleaning devices are disclosed for refurbishing sorbent materials. In one implementation among multiple implementations, a medical fluid delivery method includes: providing a sorbent cartridge including H.sup.+ZP within a casing for a treatment; and after the treatment, refurbishing the H.sup.+ZP while maintained within the casing via (i) regenerating the non-disinfected H.sup.+ZP by flowing an acid solution through the casing, (ii) rinsing the regenerated H.sup.+ZP while maintained within the casing, (iii) disinfecting the regenerated and rinsed H.sup.+ZP by flowing a disinfecting agent through the casing, and (iv) rinsing the regenerated and disinfected H.sup.+ZP while maintained within the casing. Multiple batch sorbent refurbishing implementations are also disclosed.