A dispenser for taking up and discharging fluid volumes which has an exchangeable piston-cylinder unit. The dispenser has a housing and a device for incremental distance measurement that, when there is relative movement between the piston and the cylinder, the distance traveled by the piston relative to the housing can be determined incrementally. The dispenser has a piston actuation member which can be releasably connected to the piston moving the piston in order to take up and/or discharge fluid volumes. The dispenser has a position determining device which has a first position element and a second position element. The first position element is fixed in or on the housing of the dispenser. The second position element is coupled so as to be able to move with the piston actuation member. The position determining device is for continuously sensing the position of the second position element.

Provided are methods and systems that relate to configuring a handheld analyzer. The handheld analyzer may receive an identifier from a dual design test cartridge. The parameter module disposed within the handheld analyzer may determine parameters corresponding to the received test cartridge identifier. The parameter module may then configure the handheld analyzer to perform a test with the dual designed test cartridge using the determined parameters. In an embodiment, the diagnostic test module may determine the test corresponding to the received cartridge identifier and the diagnostic test module configures the handheld analyzer to perform the determined test with the test cartridge. In another embodiment, the dual test cartridge comprises an outer enclosure and an inner enclosure. The outer enclosure comprises a parameter module capable of storing test cartridge identification and may be reused to store new test identifications.

System, method, and computer program product for improving the accuracy of blood glucose measurements in a blood glucose meter by compensating for thermal effects of the glucose meter hardware. A machine learning model is used to predict the reaction site temperature on a blood glucose test strip based on one or more temperature measurements and device status information. The model receives several inputs including at least one temperature measurement sensed near the reaction site as well as device usage and other factors that may influence the reaction site temperature. The model provides a predicted reaction site temperature to the glucometer software or firmware to be used in a blood glucose calculation.

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According to an example aspect of the present invention, there is provided a liquid handling device comprising: means for harvesting energy; energy storage arranged for storing the harvested energy in the liquid handling device; and an electronic component connected to the energy storage and configured to use the energy storage as a power source.

An acoustic liquid transfer system comprises: a processor; a source holding component configured to hold a source microplate; a destination holding component configured to hold a destination microplate; an acoustic transducer configured to cause liquid to transfer between the source and destination microplates; and a controller configured to direct movements, according to an ordered picklist, of one or more of the: source holding component, destination holding component, and acoustic transducer. The processor is configured to access an initial picklist of a plurality of source/destination pairs; obtain a current source/destination pair on the ordered picklist being created, calculate a plurality of movement metrics between the current source/destination pair and at least some of the plurality of source/destination pairs on the initial picklist but not yet on the ordered picklist, select a next source/destination pair with reference to the movement metrics: and add the next source/destination pair to the ordered picklist.

A portable detector is disclosed for detecting certain analytes of interest, such as genetic material (e.g., nucleic acids). The detector includes a reading component for the detection of the analytes, and control circuitry for controlling operation of the reading component. Processing circuitry may be included to perform both primary analysis of acquired data, and where desired, secondary analysis. Where desired, some or all of the computationally intensive tasks may be off-loaded to enhance the portability and speed of the device. The device may incorporate various types of interface, technologies for reading and analysis, positioning system interfaces, and so forth. A number of exemplary use cases and methods are also disclosed.

Described are exemplary embodiments of a handheld, powered positive displacement pipette having unique mechanisms for the retention, identification and ejection of associated pipette syringes.

The present invention generally includes methods, devices and/or kits for the detection of a COVID-19 infection in an individual by measuring the level or concentration or one or more ions present in a urine sample that is substantially free of COVID-19 RNA, antibodies, or antigen material.

The present invention provides methods and apparatus for manipulating and interrogating the contents of large numbers of microdroplets in parallel on a surface of a microfluidic chip. According to one aspect of the invention a method is provided for manipulating and inspecting microdroplets on a microfluidic chip by optically- mediated electrowetting (oEWOD), the method comprising forming, using a first optical assembly, a plurality of oEWOD traps on a surface of the chip and forming, using a second optical assembly, a second array of oEWOD traps on the surface of the chip, and making an adjustment to the first optical assembly whilst one or more of the microdroplets are held in place by second array of oEWOD traps. Apparatus comprising a microfluidic chip and first and second optical assemblies is also provided.

Systems, methods, and collection devices are disclosed for rapid, local PCR testing. The PCR testing system may be configured for use with a disposable sample collection device that includes a swab configured for collecting a biological sample from a patient; and a sample container configured to receive the swab and separate a bulk quantity of the biological sample from the swab for containment in a bulk collection chamber, which is located with the sample container, wherein the sample container is configured to meter a selected volume of the biological sample into a PCR sample tube, which contains a lyophilized master mix, releasably attachable to the sample container.