B01L2300/10

Integrated microfluidic system for culturing and testing

The present disclosure describes a microfluidic chip for culturing and in vitro testing of 3D organotypic cultures. The tests may be performed directly on the organotypic culture in the microfluidic chip. The microfluidic chip includes at least one microfluidic unit which includes two fluidic compartments, such as upper and lower, separated by a permeable supporting structure, one or more access opening for the fluidic compartments, and a set of lids interchangeable with a set of insets. The permeable support structure serves as a support for the organotypic culture. The upper and lower compartments may include inlets and outlets which allow fluids to be perfused into the lower compartment and fluids to be perfused into the upper compartment. The access opening may be closed with a lid or accommodate an inset.

FREEZE-DRYING APPARATUS AND METHOD
20220410148 · 2022-12-29 · ·

A process for freeze drying a material. The process has the steps of (a) placing material to be freeze-dried in a vessel, the vessel comprising a container having a base, and at least one wall defining an opening at one end; (b) applying a membrane to the at least one wall to thereby cover the opening, wherein the membrane comprises an aperture which, in use, is aligned with the opening; and (c) subjecting the vessel to a lyophilisation procedure, wherein the membrane is in place on the container during the lyophilisation procedure.

GENOME EXTRACTION DEVICE OF DUAL CHAMBER STRUCTURE IN WHICH OUTER CHAMBER AND BEAD CHAMBER ARE COMBINED WITH EACH OTHER

Provided is a genome extraction device to which a dual chamber structure of an outer chamber and a bead chamber is applied, more particularly a genome extraction device to which the above-described dual chamber structure is applied so that the performance of dry beads vulnerable to moisture can be maintained for a long time.

Safety cabinet, and vibration damping mechanism for fan filter unit

A biosafety cabinet includes an operation, an operation space, a front plate, an operation opening, a vibration damping mechanism and an exhaust. The vibration damping mechanism is a mechanism that floats an operation object, which is disposed in the operation space, from the operation stage. The vibration damping mechanism includes a table which supports the operation object, and a magnet which is disposed in the operation stage. The vibration damping mechanism is a mechanism that floats the operation object from the operation stage by using a magnetic force.

Low-temperature storage plant with a nitrogen withdrawal apparatus
11530862 · 2022-12-20 · ·

A storage plant for storing objects at the temperature of liquid nitrogen comprises a plurality of storage tanks arranged in a cooled chamber. A nitrogen withdrawal apparatus is provided to carry off evaporated nitrogen directly from the storage tanks before it can enter the chamber. The pressure in the storage tanks is kept below the pressure in the chamber.

METHOD FOR ENHANCED DETERMINATION OF ANALYTE CONCENTRATION IN BODY FLUID
20220381773 · 2022-12-01 ·

An analytical method for determining a concentration of an analyte is disclosed. In this method, an image of an optical test strip having a body fluid applied thereto is obtained with a camera of a mobile device. Local temperature information is received at a current location of the mobile device from a temperature source such as a remote weather information service or temperature sensor. Additional local temperature information is received by the mobile device from a thermochromic field provided on the test strip and/or on a color reference card. A processor determines a correction temperature and/or a correction temperature function using the local temperature information. The processor also determines the analyte concentration from the image captured and taking into account the correction temperature information.

AUTOMATIC ANALYSIS DEVICE

Provided is an automatic analysis device that can suppress the occurrence of condensation in a reagent cool box and can immediately drain the condensation water generated by introducing outside air. In an automatic analysis device including a reagent cool box that stores a plurality of reagent vessels while keeping the reagent vessels cool, the reagent cool box includes a drain for discharging the condensation water generated inside the reagent cool box, and an outside air introduction path that guides air outside the reagent cool box to the inside, wherein the outside air introduction path is provided along a bottom surface of the reagent cool box, and an outside air discharge port is formed toward an upper opening unit of the drain.

Microdevice for detecting aldehydes or ketones

A device and system for detecting aldehydes or ketones and, more particularly, a device and system, for detecting aldehydes or ketones, utilized in a rotating platform are provided.

MICROFLUIDIC DEVICE AND METHOD FOR QUANTIFYING CONTACT LENS DEPOSITION
20220343480 · 2022-10-27 ·

Disclosed herein are methods for quantifying contact lens deposition. An example method may comprise disposing a contact lens sample in a fluid well. The example method may comprise disposing a volume of tear fluid in the well with the contact lens sample. The example method may comprise capturing pre-rinse images of the contact lens sample. The example method may comprise rinsing the contact lens sample. The example method may comprise capturing post-rinse images of the contact lens after the rinsing. The example method may comprise determining, using one or more of the tear images or the post-rinse images, a deposition metric. The example method may comprise outputting the deposition metric.

CELL CULTURE SYSTEM
20220340847 · 2022-10-27 ·

The present invention relates to an automatic culture device using a single-use closed system flow path for culturing a cell or a tissue, and realizes reduction in manufacturing cost and high integration property of a device. A cell culture system including an automatic culture device and an information processing device. The automatic culture device includes a plurality of types of closed system flow paths possible to be installed and removed, and a plurality of culture devices. The information processing device includes: an input device configured to receive, as an input, at least one piece of data selected from a group consisting of data of an identifier of a patient, data related to a transplantation method, data related to a type of cell, data related to the required number of cells, and data related to a treatment plan; an arithmetic device configured to select, based on the input data, from options of a cell culture method, the culture devices, and the closed system flow paths, the cell culture method, the culture device, and the closed system flow path to be used; and an output device configured to output a number of the closed system flow path to be used and a number of the culture device to be used.