Provided is a centrifugal field-flow fractionation device capable of suppressing deformation of a channel member. Pressure in a channel formed inside the channel member in a centrifugal field-flow fractionation device 1 is increased by a pressure increasing mechanism 8 provided downstream of the centrifugal field-flow fractionation device 1. In this manner, an inner surface of the channel is pressed outward by a liquid sample in the channel, and an outer peripheral surface and an inner peripheral surface of the channel member can be suppressed from being recessed toward the channel side.

Provided is a centrifugal field-flow fractionation device capable of suppressing deformation of a channel member. Pressure in a channel formed inside the channel member in a centrifugal field-flow fractionation device 1 is increased by a pressure increasing mechanism 8 provided downstream of the centrifugal field-flow fractionation device 1. In this manner, an inner surface of the channel is pressed outward by a liquid sample in the channel, and an outer peripheral surface and an inner peripheral surface of the channel member can be suppressed from being recessed toward the channel side.

Centrifugal contactors that can be used for mixing or separating materials are described. The contactors include a sensing system including a communications fiber within the shaft of the contactors and access ports providing access from the communications fiber to the mixing/separating zone of the contactor. The sensing system can be utilized during operation of the contactor and can provide for detailed and accurate on-line characterization of a protocol, as well as process control and system modification as necessary during operation.

Centrifugal contactors that can be used for mixing or separating materials are described. The contactors include a sensing system including a communications fiber within the shaft of the contactors and access ports providing access from the communications fiber to the mixing/separating zone of the contactor. The sensing system can be utilized during operation of the contactor and can provide for detailed and accurate on-line characterization of a protocol, as well as process control and system modification as necessary during operation.

A centrifugal separator includes a rotating body driving and sealing structure in which a hermetically sealed space is formed between a rotating body and an outer case by sealing the inside and outside using a noncontact seal during rotation of the rotating body, in an airtight manner. A rotation coupling unit is provided at the upper end of a centrifugal cylinder, and even when the centrifugal cylinder is deformed during use causing an internal fluid to leak through a fitting portion of a bottom member to the centrifugal cylinder, the fluid leaks in the hermetically sealed space so that the driving system or the like is not contaminated.

A centrifugal separator includes a rotating body driving and sealing structure in which a hermetically sealed space is formed between a rotating body and an outer case by sealing the inside and outside using a noncontact seal during rotation of the rotating body, in an airtight manner. A rotation coupling unit is provided at the upper end of a centrifugal cylinder, and even when the centrifugal cylinder is deformed during use causing an internal fluid to leak through a fitting portion of a bottom member to the centrifugal cylinder, the fluid leaks in the hermetically sealed space so that the driving system or the like is not contaminated.

An active rotating separator is disclosed, comprising a separator drum arranged to receive multiphase fluid via an upstream end and to deliver separated fluid phases from a downstream end of the drum. An electric motor is installed in the flow through the drum, the motor operable to generate rotation in the fluid flow that passes through the drum, the motor comprising an open rotor permitting through-flow of fluid through the motor.

An active rotating separator is disclosed, comprising a separator drum arranged to receive multiphase fluid via an upstream end and to deliver separated fluid phases from a downstream end of the drum. An electric motor is installed in the flow through the drum, the motor operable to generate rotation in the fluid flow that passes through the drum, the motor comprising an open rotor permitting through-flow of fluid through the motor.

Cell separation systems and methods of separating cells are disclosed. In an embodiment, a cell separation system is described that comprises a non-transitory storage device that executes a centrifugation program to separate cell volume from biologic material volume; a heating mechanism; a containment mechanism; and an assembly comprised of a single-walled centrifugation bowl. In an embodiment, methods of separating cells are disclosed whereby cells are separated by agitating a volume of biologic material and a volume digestion media to form a digested volume of biologic material; centrifuging the digested volume of biologic material; removing a portion of a resulting waste via at least one fluid outlet; isolating a different portion of the waste, and removing the concentrated cell volumes from the reservoir.

Cell separation systems and methods of separating cells are disclosed. In an embodiment, a cell separation system is described that comprises a non-transitory storage device that executes a centrifugation program to separate cell volume from biologic material volume; a heating mechanism; a containment mechanism; and an assembly comprised of a single-walled centrifugation bowl. In an embodiment, methods of separating cells are disclosed whereby cells are separated by agitating a volume of biologic material and a volume digestion media to form a digested volume of biologic material; centrifuging the digested volume of biologic material; removing a portion of a resulting waste via at least one fluid outlet; isolating a different portion of the waste, and removing the concentrated cell volumes from the reservoir.