The present invention relates to a solid form, particularly to a 3D-printed immediate release solid dosage form (e.g. based on a pharmaceutical, nutraceutical, or food supplement composition). To overcome some of the solubility and disintegration problems inherited by 3D-printed solid dosage forms, the solid form comprises one or more channels, generally in the form of tubular passages or grooves, through the body of the solid form or the surface thereof.

The invention pertains to the use of sophisticated chemical formulation and spectroscopic design methods to select taggants compatible with the 3D print medium that are easily detected spectroscopically but otherwise compatible with the product, structural integrity and stability, and aesthetics. A spectral pattern employs a different chemical or combination of chemicals to alter the formulation of all or some portion of the printed object so that its authenticity can be monitored later using a spectrometer.

Embodiments of the present disclosure relate to advanced polishing pads with tunable chemical, material and structural properties, and new methods of manufacturing the same. According to one or more embodiments of the disclosure, it has been discovered that a polishing pad with improved properties may be produced by an additive manufacturing process, such as a three-dimensional (3D) printing process. Embodiments of the present disclosure thus may provide an advanced polishing pad that has discrete features and geometries, formed from at least two different materials that include functional polymers, functional oligomers, reactive diluents, addition polymer precursor compounds, catalysts, and curing agents. For example, the advanced polishing pad may be formed from a plurality of polymeric layers, by the automated sequential deposition of at least one polymer precursor composition followed by at least one curing step, wherein each layer may represent at least one polymer composition, and/or regions of different compositions. Embodiments of the disclosure further provide a polishing pad with polymeric layers that may be interpenetrating polymer networks.

A cross-linkable powder for use in a selective laser sintering (SLS) process for additive manufacturing is disclosed as well as a novel manufacturing process to form a 3D object using said cross-linkable powder. The manufacturing process makes it possible to create interlayer covalent bondings between deposited layers of cross-linkable powder such that 3D printed objects are achieved having improved mechanical strength, less object deformation and/or no warping.

Novel support material formulations, characterized as providing a cured support material with improved dissolution rate, while maintaining sufficient mechanical strength, are disclosed. The formulations comprise a water-miscible non-curable polymer, a first water-miscible, curable material and a second, water-miscible material that is selected capable of interfering with intermolecular interactions between polymeric chains formed upon exposing the first water-miscible material to curing energy. Methods of fabricating a three-dimensional object, and a three-dimensional object fabricated thereby are also disclosed.

The present invention provides a thermosetting material, which contains the following components (A) to (C) and which, when measured with a rotational viscometer at a constant shear rate (JIS K7117-2:1999), exhibits a viscosity at 25 C. and 10 s.sup.1 of 5 Pa.Math.s or more and 200 Pa.Math.s or less and, when measured with a rotational viscometer at a constant shear rate in the same manner as above, exhibits a viscosity at 25 C. and a shear rate of 100 s.sup.1 of 0.3 Pa.Math.s or more and 50 Pa.Math.s or less. (A): a (meth) acrylate compound in which a substituted or unsubstituted alicyclic hydrocarbon group having 6 or more carbon atoms is ester-bonded, and which, when measured with a rotational viscometer at a constant shear rate in the same manner as above, exhibits a viscosity of 5 to 300 mPa.Math.s as a viscosity measured at 25 C. and 10 to 100 s.sup.1; (B): spherical silica; and (C): a black pigment.

A material that can be formed into a porous prosthetic sleeve liner that provides particularly useful benefits for prosthetics. The material is breathable and sweat-absorbing, thus minimizing skin morbidity when used as a prosthetic liner. The material can include hydrophilic-lined continuous pores within a hydrophobic polymer, wherein the hydrophilic lining is crosslinked together with the hydrophobic polymer via non-degradable covalent interactions using chain crosslinkers.

Additives for three-dimensional build materials or inks are described herein which, in some embodiments, can impart flame retardant properties and/or structural enhancements to articles printed from the build materials. In some embodiments, such an additive comprises a compound of Formula I herein, wherein L and Z are ring substituents comprising at least one polymerizable point of unsaturation, and wherein R.sup.1 and R.sup.2 are independently selected from the group consisting of alkylene and alkenylene, and R.sup.3-R.sup.6 each represent one to four optional ring substituents, each one of the one to four ring substituents independently selected from the group consisting of alkyl, heteroalkyl, haloalkyl, halo, hydroxyl, alkoxy, amine, amide, and ether, and wherein n is an integer from 1 to 7.

Methods of additive manufacturing, binder compositions for additive manufacturing, and articles produced by and/or associated with methods of additive manufacturing are generally described.

Compositions including a combination of (meth)acryloyl-terminated monomers and oligomers prepared by co-reacting reactants having active hydrogen groups with an acrylating agent are disclosed. Polymerizates formed using the combinations of (meth)acryloyl-terminated monomers and oligomers exhibit a high hardness, excellent thermomechanical properties, and a high refractive index. The compositions can be used to fabricate optical components.