Described herein is a method of forming individual tubes or sachets containing fluent material, and a packaging machine for doing so, are described. The side of the foil which will be in contact with the fluent material when the package is formed is exposed to plasma in mist or aerosol form as the tube or sachet is formed from a strip of laminate material (1), which is folded about a former (2) into a closed tube or sachet which passes over the open end of a dispensing tube (3) from which the fluent material is dispensed. A mist of plasma is injected into the interior of the material tube as it is formed, extracted from the area once it has passed over the interior walls of the laminate tube.

A method of filling pharmaceutical containers includes: filling a first plurality of containers, the first plurality of containers being supported by a first holder supported on a first step of a first transport and packaging container defining a first step height, the filling includes moving filling needles of a filling device to a filling needle height and dispensing a substance into each of the first plurality of containers; and filling a second plurality of containers, the second plurality of containers being supported by a second holder supported on a second step of a second transport and packaging container defining a second step height equal to the first step height, the filling includes moving the filling needles to the filling needle height and dispensing the substance into each of the second plurality of containers, the second plurality of containers differ from the first plurality of containers in at least one aspect.

A method of filling pharmaceutical containers includes: filling a first plurality of containers, the first plurality of containers being supported by a first holder supported on a first step of a first transport and packaging container defining a first step height, the filling includes moving filling needles of a filling device to a filling needle height and dispensing a substance into each of the first plurality of containers; and filling a second plurality of containers, the second plurality of containers being supported by a second holder supported on a second step of a second transport and packaging container defining a second step height equal to the first step height, the filling includes moving the filling needles to the filling needle height and dispensing the substance into each of the second plurality of containers, the second plurality of containers differ from the first plurality of containers in at least one aspect.

The invention is in the field of cultured meat. In particular the invention is related to a method for aseptic packaging of cultured tissue and a system suitable for this method. The method comprises the steps of producing the cultured tissue, harvesting the cultured tissue, transferring the cultured tissue to a sterile package and sealing the sterile package, wherein all steps are executed under aseptic conditions.

There is described a packaging apparatus for forming a plurality of sealed packages-comprising conveyor for advancing a web of packaging material along an advancement path, an isolation chamber, a tube forming device adapted to form a tube from the, in use, advancing web of packaging material, a sealing device adapted to longitudinally seal the tube, a support structure carrying at least the tube forming device, a filling device for continuously filling the tube formed by the tube forming device, a package forming unit adapted to form and seal the packages from the, in use, advancing tube formed by the tube forming device and filled by the filling device. The support structure comprises at least one support column at least indirectly carrying the tube forming device and extending parallel to the longitudinal axis of the tube forming device.

There is described a packaging apparatus for forming a plurality of sealed packages-comprising conveyor for advancing a web of packaging material along an advancement path, an isolation chamber, a tube forming device adapted to form a tube from the, in use, advancing web of packaging material, a sealing device adapted to longitudinally seal the tube, a support structure carrying at least the tube forming device, a filling device for continuously filling the tube formed by the tube forming device, a package forming unit adapted to form and seal the packages from the, in use, advancing tube formed by the tube forming device and filled by the filling device. The support structure comprises at least one support column at least indirectly carrying the tube forming device and extending parallel to the longitudinal axis of the tube forming device.

An on-body injector system includes a drug container assembly including a container, a seal member, and a sealing interface between the seal member and the container. The container includes an opening and the seal member at least partially covers the opening in the container. A fluid pathway assembly is coupled to the drug container assembly and includes a needle that is movable between a storage position, in which a point of the needle is spaced from the seal member, and a delivery position, in which the point of the needle is disposed at least partially through the seal member. A radiation generator is configured to emit rays of radiation to sterilize and/or disinfect the sealing interface. A barrier is disposed adjacent to the sealing interface and has an opening. At least a portion of the drug container assembly is positioned adjacent to the opening in the barrier.

An on-body injector system includes a drug container assembly including a container, a seal member, and a sealing interface between the seal member and the container. The container includes an opening and the seal member at least partially covers the opening in the container. A fluid pathway assembly is coupled to the drug container assembly and includes a needle that is movable between a storage position, in which a point of the needle is spaced from the seal member, and a delivery position, in which the point of the needle is disposed at least partially through the seal member. A radiation generator is configured to emit rays of radiation to sterilize and/or disinfect the sealing interface. A barrier is disposed adjacent to the sealing interface and has an opening. At least a portion of the drug container assembly is positioned adjacent to the opening in the barrier.

A sterilization method includes irradiating flexible bags, in particular, bags of the type that can contain solutions of human plasma proteins for therapeutic use. The sterilization method includes electron beam irradiation. An in-line method for filling flexible bags of the type that can contain solutions of human plasma proteins for therapeutic use can use the sterilization method.

A sterilization method includes irradiating flexible bags, in particular, bags of the type that can contain solutions of human plasma proteins for therapeutic use. The sterilization method includes electron beam irradiation. An in-line method for filling flexible bags of the type that can contain solutions of human plasma proteins for therapeutic use can use the sterilization method.