The present invention is directed to methods for filling a container wherein the filled container has no headspace. The present invention is further directed to methods for stabilizing an aqueous drug substance solution by filling a container with the aqueous drug substance solution wherein the filled container has no headspace. The present invention is further directed to methods for detecting headspace in a container.

A welding station for welding parts of electronic cigarettes includes feeding means, set in a feeding area for feeding parts of electronic cigarettes to be welded; welding means, set in a welding area, downstream of the feeding area, for welding the parts of electronic cigarettes; and a transfer device, set between the feeding means and the welding means for receiving from the feeding means the parts of electronic cigarettes to be welded and transferring them from the feeding area to the welding area. The transfer device includes a first transfer sector and a second transfer sector, pre-arranged for receiving from the feeding means, respectively, first parts and second parts of electronic cigarettes to be welded and transferring them into the welding area. The first transfer sector and the second transfer sector are mobile in rotation about an axis, independently of one another.

Methods and systems for filling a muffler body with a fibrous material prior to completing assembly of the muffler body are disclosed. The muffler body is composed of two half shells and the fibrous material is injected between the shells by a filling nozzle.

An isolator system for filling a container with a liquid, the isolator system comprises a filling module having a filling station for filling the container with the liquid, a stopper placing station for placing a stopper on the filled container, and a plurality of handling devices for handling the container within the filling module; a first transfer station for transferring the container to be filled into the filling module; a second transfer station for transferring the filled container out of the filling module; and a control device. The present application also discloses a transfer station for transferring a container and several methods.

In one general aspect, a method for filling multiple containers with a pharmaceutical product is disclosed, which comprises decontaminating sealed nested materials in a transfer chamber, removing from the sealed nested materials one or both of a container nest holding the multiple containers and a closure nest holding multiple closures, transferring from the transfer chamber to a controlled environment enclosure the removed nest, aseptically filling the containers with the pharmaceutical product, and closing the containers with the multiple closures. The nests are configured to allow multiple closures and containers to be simultaneously aligned concentrically, and closed simultaneously. Spring-loaded retaining structures on the closure nest allow it to releasably retain multiple closures above the corresponding multiple containers. In some embodiments the spring-loaded features are monolithically integrated with the closure nest. The product may be lyophilized in partially sealed containers while the sealing closures are releasably retained by the closure nest.

Packaging for liquid food, where the packaging has an outer casing (2) of cardboard, an inner bag (8) of plastic foil which consists of e.g. completely recyclable bio-polyethylene plastic, where the inner bag is arranged inside the outer casing (2) and completely fills it when the inner bag is filled with the food, and an opening module, here called MF module (12), which contains an emptying device and a filling device arranged on a plastic disc (14), wherein the emptying device comprises an emptying channel (13) and a stopper (19) and where the filling device comprises a filling channel (25) and a filling plug (26) and wherein the MF module (12) is connected to the inner bag (8) by that the underside of the plastic disc (14) is welded to the outside of the inner bag so that the emptying channel (13) connected to a hole (11) in the inner bag (8) where the filling channel (25) opens into the emptying channel (13) is connected to the outer cover (2) in that top flaps (6a-6d) of the outer casing are attached to a slot (17) in the plastic disc (14) along the side edges thereof. The application also includes a method for filling the packaging and a method for producing an inner bag for the packaging.

A method of packing a temperature sensitive product utilizes a temperature controlled product shipper that includes a phase change material bladder which can be filled with a preconditioned brined-slurry PCM at the point of packaging. The temperature sensitive product is contained within a product box or master case, which is in turn packed inside an insulated liner and an outer box. The PCM bladder fits between the master case and the insulated liner and is filled with the preconditioned flowable PCM at the point of packing just before closing the box for shipment.

A device for closing a chamber of a container having an opening for accessing the chamber comprises a plunger, a plunger seat, a container carrier and a spacer. The plunger seat releasably holds the plunger in a predefined alignment. The container carrier is arranged to be connected to the container in a predefined position and alignment in relation to the opening of the container. The spacer is arranged to position and align the plunger seat adjacent to and distant from the container carrier such that the opening of the container is open when the container is connected to the container carrier.

A tube filling machine (1) adapted to fill different types of empty tubes (18) simultaneously, where the filling machine (1) comprises a grouping device (11), a transfer device (9), a conveyor (7) and a filling device (2) comprising a plurality of filling nozzles (3, 4, 5, 6), where the grouping device (11) comprises a first supply tray (13) with a first type of tubes, a second supply tray (14) with a second type of tubes, a receiving tray (17) and a pick-up head (12), where the transfer device (9) is adapted to transfer a grouped row of empty tubes (18) from the receiving tray (17) to the conveyor (7), where the grouping device (11) is adapted to place a plurality of groups (21) of empty tubes adjacent each other in the receiving tray (17), where a group (21) comprises a row of the first type of tubes and a row of the second type of tubes, that the transfer device (9) is adapted to transfer a row of grouped empty tubes from the receiving tray (17) to the conveyor (9), and where the filling nozzles (3, 4, 5, 6) are adapted to fill the grouped empty tubes with different content.

Systems and methods permit filling containers with a product. A filling arm is disposed within a chamber. An optical sensor is configured to sense openings of the containers within the chamber. Locations of the sensed openings are used to guide the filling arm to fill the containers with a product.