C07C211/23

Substituted amines as disrupters of ABETA42 oligomer formation
11827582 · 2023-11-28 · ·

The present disclosure provides small molecule drugs and pharmaceutical compositions for the treatment and prevention of diseases related to the formation of Aβ42 oligomers in a subject. It further provides a method of reducing formation of or disrupting Aβ42 oligomers in a subject, the method comprising the step of administering to the subject in need thereof a therapeutically effective amount of a pharmaceutical composition. One such compound is a compound of formula 120: ##STR00001##

Cobalt complexes, process for preparation and use thereof

The present invention discloses a cobalt compound of formula (I), a process for the preparation and use thereof. The present invention further relates to a pharmaceutical composition and a method inhibition of Tau Aggregation in a subject in need thereof using compound of formula (I). ##STR00001##

Cobalt complexes, process for preparation and use thereof

The present invention discloses a cobalt compound of formula (I), a process for the preparation and use thereof. The present invention further relates to a pharmaceutical composition and a method inhibition of Tau Aggregation in a subject in need thereof using compound of formula (I). ##STR00001##

COBALT COMPLEXES, PROCESS FOR PREPARATION AND USE THEREOF

The present invention discloses a cobalt compound of formula (I), a process for the preparation and use thereof. The present invention further relates to a pharmaceutical composition and a method inhibition of Tau Aggregation in a subject in need thereof using compound of formula (I).

##STR00001##

COBALT COMPLEXES, PROCESS FOR PREPARATION AND USE THEREOF

The present invention discloses a cobalt compound of formula (I), a process for the preparation and use thereof. The present invention further relates to a pharmaceutical composition and a method inhibition of Tau Aggregation in a subject in need thereof using compound of formula (I).

##STR00001##

SYNTHESIS OF RAS INHIBITORS

The present invention relates to Ras inhibitors and to methods for preparing Ras inhibitors.

SYNTHESIS OF RAS INHIBITORS

The present invention relates to Ras inhibitors and to methods for preparing Ras inhibitors.