Patent classifications
C07C233/34
Use of small molecule inhibitors to KLF10 for modulation of T regulatory cells and cancer immunotherapy
The invention relates to compositions and methods for inhibiting Krüppel-like Factor 10 (KLF10) for modulation of T regulatory cells and cancer immunotherapy.
Materials that provide bioresistance and/or defoaming and slower cooling properties for aqueous quenchants
Methods and compositions are provided for heat treating, e.g. quenching a metal. The quenching composition includes a composition that comprises a polyamidopolyamine compound having a molecular weight of about 500 to about 100,000 and comprising a pendent amino group; and/or a non-polymeric amidoamine having a molecular weight of about 290 to about 5000 and comprising an amino group; and a hydroxyl containing diluent. These compositions impart one or more of the functions of quenching, lubricity, anti/low foaming and/or bioresistance to the quenching fluid.
Materials that provide bioresistance and/or defoaming and slower cooling properties for aqueous quenchants
Methods and compositions are provided for heat treating, e.g. quenching a metal. The quenching composition includes a composition that comprises a polyamidopolyamine compound having a molecular weight of about 500 to about 100,000 and comprising a pendent amino group; and/or a non-polymeric amidoamine having a molecular weight of about 290 to about 5000 and comprising an amino group; and a hydroxyl containing diluent. These compositions impart one or more of the functions of quenching, lubricity, anti/low foaming and/or bioresistance to the quenching fluid.
Compositions and Methods of Using Polyamidopolyamines and Non-Polymeric Amidoamines
Compositions comprising a polyamidopolyamine and/or a non-poly-meric amidoamine are disclosed for imparting multiple desired characteristics to a variety of industrial compositions. In certain embodiments, these compositions are prepared by condensing a C.sub.4 to C.sub.16 poly basic acid, monobasic acid or derivative thereof with a polyamine comprising a primary amino group, and in the presence of an optional organic diluent. Certain specific polyamidopolyamine and a non-polymeric amidoamine formulae and compositions containing same are disclosed, as are methods of use of these compositions.
Compositions and Methods of Using Polyamidopolyamines and Non-Polymeric Amidoamines
Compositions comprising a polyamidopolyamine and/or a non-poly-meric amidoamine are disclosed for imparting multiple desired characteristics to a variety of industrial compositions. In certain embodiments, these compositions are prepared by condensing a C.sub.4 to C.sub.16 poly basic acid, monobasic acid or derivative thereof with a polyamine comprising a primary amino group, and in the presence of an optional organic diluent. Certain specific polyamidopolyamine and a non-polymeric amidoamine formulae and compositions containing same are disclosed, as are methods of use of these compositions.
Functionalized graphene barrier element
Described herein are functionalized graphene compositions that have gas, fluid, and/or vapor resistant properties. Also described are barrier elements based on the aforementioned compositions. Also described is a barrier device that incorporates the barrier element and further comprises a substrate and a protective coating, encompassing the barrier element.
Functionalized graphene barrier element
Described herein are functionalized graphene compositions that have gas, fluid, and/or vapor resistant properties. Also described are barrier elements based on the aforementioned compositions. Also described is a barrier device that incorporates the barrier element and further comprises a substrate and a protective coating, encompassing the barrier element.
USE OF SMALL MOLECULE INHIBITORS TO KLF10 FOR MODULATION OF T REGULATORY CELLS AND CANCER IMMUNOTHERAPY
The invention relates to compositions and methods for inhibiting Krppel-like Factor 10 (KLF10) for modulation of T regulatory cells and cancer immunotherapy.