C07C233/34

Use of small molecule inhibitors to KLF10 for modulation of T regulatory cells and cancer immunotherapy

The invention relates to compositions and methods for inhibiting Krüppel-like Factor 10 (KLF10) for modulation of T regulatory cells and cancer immunotherapy.

Materials that provide bioresistance and/or defoaming and slower cooling properties for aqueous quenchants

Methods and compositions are provided for heat treating, e.g. quenching a metal. The quenching composition includes a composition that comprises a polyamidopolyamine compound having a molecular weight of about 500 to about 100,000 and comprising a pendent amino group; and/or a non-polymeric amidoamine having a molecular weight of about 290 to about 5000 and comprising an amino group; and a hydroxyl containing diluent. These compositions impart one or more of the functions of quenching, lubricity, anti/low foaming and/or bioresistance to the quenching fluid.

Materials that provide bioresistance and/or defoaming and slower cooling properties for aqueous quenchants

Methods and compositions are provided for heat treating, e.g. quenching a metal. The quenching composition includes a composition that comprises a polyamidopolyamine compound having a molecular weight of about 500 to about 100,000 and comprising a pendent amino group; and/or a non-polymeric amidoamine having a molecular weight of about 290 to about 5000 and comprising an amino group; and a hydroxyl containing diluent. These compositions impart one or more of the functions of quenching, lubricity, anti/low foaming and/or bioresistance to the quenching fluid.

Compositions and Methods of Using Polyamidopolyamines and Non-Polymeric Amidoamines

Compositions comprising a polyamidopolyamine and/or a non-poly-meric amidoamine are disclosed for imparting multiple desired characteristics to a variety of industrial compositions. In certain embodiments, these compositions are prepared by condensing a C.sub.4 to C.sub.16 poly basic acid, monobasic acid or derivative thereof with a polyamine comprising a primary amino group, and in the presence of an optional organic diluent. Certain specific polyamidopolyamine and a non-polymeric amidoamine formulae and compositions containing same are disclosed, as are methods of use of these compositions.

Compositions and Methods of Using Polyamidopolyamines and Non-Polymeric Amidoamines

Compositions comprising a polyamidopolyamine and/or a non-poly-meric amidoamine are disclosed for imparting multiple desired characteristics to a variety of industrial compositions. In certain embodiments, these compositions are prepared by condensing a C.sub.4 to C.sub.16 poly basic acid, monobasic acid or derivative thereof with a polyamine comprising a primary amino group, and in the presence of an optional organic diluent. Certain specific polyamidopolyamine and a non-polymeric amidoamine formulae and compositions containing same are disclosed, as are methods of use of these compositions.

Functionalized graphene barrier element
09969682 · 2018-05-15 · ·

Described herein are functionalized graphene compositions that have gas, fluid, and/or vapor resistant properties. Also described are barrier elements based on the aforementioned compositions. Also described is a barrier device that incorporates the barrier element and further comprises a substrate and a protective coating, encompassing the barrier element.

Functionalized graphene barrier element
09969682 · 2018-05-15 · ·

Described herein are functionalized graphene compositions that have gas, fluid, and/or vapor resistant properties. Also described are barrier elements based on the aforementioned compositions. Also described is a barrier device that incorporates the barrier element and further comprises a substrate and a protective coating, encompassing the barrier element.

USE OF SMALL MOLECULE INHIBITORS TO KLF10 FOR MODULATION OF T REGULATORY CELLS AND CANCER IMMUNOTHERAPY
20170121318 · 2017-05-04 · ·

The invention relates to compositions and methods for inhibiting Krppel-like Factor 10 (KLF10) for modulation of T regulatory cells and cancer immunotherapy.