Patent classifications
C07C233/50
SHMT INHIBITORS AND USES THEREOF
The present invention provides compounds, compositions thereof, and methods of using the same.
SHMT INHIBITORS AND USES THEREOF
The present invention provides compounds, compositions thereof, and methods of using the same.
TEAD INHIBITORS AND USES THEREOF
The present disclosure provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
Dimethyl-nonatetraenyl-trimethyl-cyclohexyl compounds and uses thereof
This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a dimethyl-nonatetraenyl-trimethyl-cyclohexyl structure useful as therapeutics for the treatment of subjects suffering from disorders characterized by abnormal proliferation and/or abnormal differentiation of cells, in particular of cells of which the growth and differentiation is sensitive to the actions of retinoids.
Dimethyl-nonatetraenyl-trimethyl-cyclohexyl compounds and uses thereof
This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a dimethyl-nonatetraenyl-trimethyl-cyclohexyl structure useful as therapeutics for the treatment of subjects suffering from disorders characterized by abnormal proliferation and/or abnormal differentiation of cells, in particular of cells of which the growth and differentiation is sensitive to the actions of retinoids.
SHMT INHIBITORS AND USES THEREOF
The present invention provides compounds, compositions thereof, and methods of using the same.
SHMT INHIBITORS AND USES THEREOF
The present invention provides compounds, compositions thereof, and methods of using the same.
Small Molecule Allosteric Modulators of Serotonin (5-HT) 5-HT2C and 5-HT2A Receptors
The present invention relates to novel 5HT receptor modulators, such as compounds of the general Formula (I) and general Formula (II):
##STR00001##
or a pharmaceutically acceptable salt thereof. Methods of using the compounds include, for example, modulation of 5-hydroxytryptamine (5-HT) receptor subtypes, including 5-hydroxytryptamine 2A receptor and/or 5-hydroxytryptamine 2C receptor, and treatment of a condition or disease where the treatment is associated with the modulation of 5-hydroxytryptamine 2A receptor and/or 5-hydroxytryptamine 2C receptor.
DIMETHYL-NONATETRAENYL-TRIMETHYL-CYCLOHEXYL COMPOUNDS AND USES THEREOF
This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a dimethyl-nonatetraenyl-trimethyl-cyclohexyl structure useful as therapeutics for the treatment of subjects suffering from disorders characterized by abnormal proliferation and/or abnormal differentiation of cells, in particular of cells of which the growth and differentiation is sensitive to the actions of retinoids.