The present invention provides compounds of Formula (I): ##STR00001##
or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein all the variables are as defined herein. These compounds are selective LPA receptor inhibitors.

The present invention provides compounds of Formula (I): ##STR00001##
or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein all the variables are as defined herein. These compounds are selective LPA receptor inhibitors.

Disclosed is an antifreezing coolant composition, which does not include glycol but includes environmentally friendly materials, such as a carboxylic acid salt, an anthranilamide compound, a corrosion inhibitor and a triazole compound. The antifreezing coolant composition may form a thin film on the metal surface in cooling systems for vehicles to thereby exhibit high corrosion resistance at low and high temperatures, superior antifreezing performance at low temperatures, and superior cooling performance at high temperatures.

A lamp for a photochemical reactor, including: a support member made of a material having a thermal conductivity greater than or equal to 100W/mK at 20° C. and including at least one channel configured to contain a coolant fluid; at least one printed circuit mounted on the support member; and at least one light-emitting diode mounted on the printed circuit. A photochemical reactor including such a lamp, and a method for preparing a cycloalkanone oxime or a lactam using such a lamp.

A lamp for a photochemical reactor, including: a support member made of a material having a thermal conductivity greater than or equal to 100W/mK at 20° C. and including at least one channel configured to contain a coolant fluid; at least one printed circuit mounted on the support member; and at least one light-emitting diode mounted on the printed circuit. A photochemical reactor including such a lamp, and a method for preparing a cycloalkanone oxime or a lactam using such a lamp.

The present invention provides compounds of Formula (I):

##STR00001##

or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein all the variables are as defined herein. These compounds are selective LPA receptor inhibitors.

The present invention provides compounds of Formula (I):

##STR00001##

or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein all the variables are as defined herein. These compounds are selective LPA receptor inhibitors.

Provided are a photoirradiation device equipped with: a first optically transparent container for covering a light-emitting body provided with light-emitting diodes; a liquid phase section provided on the outside thereof and formed from a liquid having a refractive index closer to that of the first optically transparent container than that of a gas forming a gas phase section inside the first optically transparent container; and a second optically transparent container for covering the liquid phase section, a photoreaction method using the photoirradiation device, and a method for producing lactam by using the photoreaction method. The reflection of light between a target liquid and a light-emitting diode light source is suppressed, and a desired photoirradiation can be achieved with a high optical transparency.

Provided are a photoirradiation device equipped with: a first optically transparent container for covering a light-emitting body provided with light-emitting diodes; a liquid phase section provided on the outside thereof and formed from a liquid having a refractive index closer to that of the first optically transparent container than that of a gas forming a gas phase section inside the first optically transparent container; and a second optically transparent container for covering the liquid phase section, a photoreaction method using the photoirradiation device, and a method for producing lactam by using the photoreaction method. The reflection of light between a target liquid and a light-emitting diode light source is suppressed, and a desired photoirradiation can be achieved with a high optical transparency.

Provided is a photochemical reaction device wherein two partitions formed from an optically transparent material are arranged apart from each other between a light source and a reaction liquid, and an optically transparent fluid introduction/discharge means for introducing an optically transparent fluid between the partitions and discharging the fluid and a state change detection means for detecting a change in the state of the optically transparent fluid at the discharge side of the optically transparent fluid introduction/discharge means are provided. Also provided are a photochemical reaction method that uses the photochemical reaction device and a lactam production method that uses the photochemical reaction method. The present invention prevents decreases in the performance of the light source even when the optically transparent material in the photochemical reaction device is damaged, and makes it possible to reliably prevent ignition even if the reaction liquid is a flammable liquid.