There is disclosed a process for preparing taurine from alkali isethionate by reacting alkali taurinates in the solution of ammonolysis reaction of alkali isethionate with ammonium bisulfite or ammonium sulfite to obtain taurine and to regenerate alkali bisulfite or alkali sulfite, which is used to react with ethylene oxide to afford alkali isethionate.

There is disclosed a process for preparing taurine from alkali isethionate by reacting alkali taurinates in the solution of ammonolysis reaction of alkali isethionate with ammonium bisulfite or ammonium sulfite to obtain taurine and to regenerate alkali bisulfite or alkali sulfite, which is used to react with ethylene oxide to afford alkali isethionate.

A system for preparing high-purity taurine and salt. The system can be used in an ethylene oxide process for producing taurine. The system includes an addition reaction device, an ammonolysis reaction device, an evaporation device, and a taurine salt concentrated solution collection device. The ammonolysis reaction device is provided with a metal salt inlet, the taurine salt concentrated solution collection device is connected with an ion exchange system for ion exchange, the ion exchange system is provided with an acid inlet, an adsorption solution outlet and an eluate outlet, the adsorption solution outlet of the ion exchange system is connected with a taurine extraction device, the eluate outlet of the ion exchange system is connected with a salt extraction device, and the ion exchange system is provided with a purified water inlet, an adsorption unit cleaning water outlet and an elution unit cleaning water outlet.

A system for preparing high-purity taurine and salt. The system can be used in an ethylene oxide process for producing taurine. The system includes an addition reaction device, an ammonolysis reaction device, an evaporation device, and a taurine salt concentrated solution collection device. The ammonolysis reaction device is provided with a metal salt inlet, the taurine salt concentrated solution collection device is connected with an ion exchange system for ion exchange, the ion exchange system is provided with an acid inlet, an adsorption solution outlet and an eluate outlet, the adsorption solution outlet of the ion exchange system is connected with a taurine extraction device, the eluate outlet of the ion exchange system is connected with a salt extraction device, and the ion exchange system is provided with a purified water inlet, an adsorption unit cleaning water outlet and an elution unit cleaning water outlet.

Pyrimidone compounds defined herein exhibit human neutrophil elastase inhibitory properties and are useful for treating diseases and condition in which HNE is implicated.

Pyrimidone compounds defined herein exhibit human neutrophil elastase inhibitory properties and are useful for treating diseases and condition in which HNE is implicated.

There is disclosed a process for producing taurine from ammonium isethionate by the ammonolysis of alkali isethionate in the presence of alkali ditaurinate or alkali tritaurinate, or their mixture, to inhibit the formation of byproducts and to continuously convert the byproducts of the ammonolysis reaction to alkali taurinate. Alkali taurinate is reacted with ammonium isethionate to obtain taurine and to regenerate alkali isethionate. The production yield is increased to from 90% to nearly quantitative. The ammonolysis reaction is catalyzed by alkali salts of hydroxide, sulfate, sulfite, phosphate, or carbonate.

There is disclosed a process for producing taurine from ammonium isethionate by the ammonolysis of alkali isethionate in the presence of alkali ditaurinate or alkali tritaurinate, or their mixture, to inhibit the formation of byproducts and to continuously convert the byproducts of the ammonolysis reaction to alkali taurinate. Alkali taurinate is reacted with ammonium isethionate to obtain taurine and to regenerate alkali isethionate. The production yield is increased to from 90% to nearly quantitative. The ammonolysis reaction is catalyzed by alkali salts of hydroxide, sulfate, sulfite, phosphate, or carbonate.

A lyophilisate of treosulfan is described which possesses favourable characteristics in terms of a short reconstitution time and a high purity and stability and which is particularly useful in the treatment of cancer and for conditioning therapy before transplantation of bone marrow or blood stem cells.

A lyophilisate of treosulfan is described which possesses favourable characteristics in terms of a short reconstitution time and a high purity and stability and which is particularly useful in the treatment of cancer and for conditioning therapy before transplantation of bone marrow or blood stem cells.