Patent classifications
C07C309/18
Method for preparing taurine
There is disclosed a process for preparing taurine from alkali isethionate by reacting alkali taurinates in the solution of ammonolysis reaction of alkali isethionate with ammonium bisulfite or ammonium sulfite to obtain taurine and to regenerate alkali bisulfite or alkali sulfite, which is used to react with ethylene oxide to afford alkali isethionate.
Method for preparing taurine
There is disclosed a process for preparing taurine from alkali isethionate by reacting alkali taurinates in the solution of ammonolysis reaction of alkali isethionate with ammonium bisulfite or ammonium sulfite to obtain taurine and to regenerate alkali bisulfite or alkali sulfite, which is used to react with ethylene oxide to afford alkali isethionate.
Phenyl containing compound, intermediate thereof, preparation method therefor and application thereof
A phenyl-containing compound, an intermediate thereof, a preparation method therefor and an application thereof. Provided is a compound represented by formula I or a pharmaceutically acceptable salt thereof, where R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 are independently hydrogen, C.sub.1-C.sub.6 alkyl, C.sub.1-C.sub.6 alkoxy or C(═O)OR.sup.8; where R.sup.8 is C.sub.1-C.sub.4 alkyl; R.sup.6 is (II), (III) or (IV); and R.sup.7 is —OH, —NH.sub.2, —NHCH.sub.3, —N(CH.sub.3).sub.2 or C.sub.1-4 alkoxy. The compound has a low critical micelle concentration (CMC) and good dilution resistance and is capable of enclosing an insoluble drug to form a small-molecule micelle having a high drug loading capacity and good stability. ##STR00001##
Phenyl containing compound, intermediate thereof, preparation method therefor and application thereof
A phenyl-containing compound, an intermediate thereof, a preparation method therefor and an application thereof. Provided is a compound represented by formula I or a pharmaceutically acceptable salt thereof, where R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 are independently hydrogen, C.sub.1-C.sub.6 alkyl, C.sub.1-C.sub.6 alkoxy or C(═O)OR.sup.8; where R.sup.8 is C.sub.1-C.sub.4 alkyl; R.sup.6 is (II), (III) or (IV); and R.sup.7 is —OH, —NH.sub.2, —NHCH.sub.3, —N(CH.sub.3).sub.2 or C.sub.1-4 alkoxy. The compound has a low critical micelle concentration (CMC) and good dilution resistance and is capable of enclosing an insoluble drug to form a small-molecule micelle having a high drug loading capacity and good stability. ##STR00001##
AMPHOTERIC COMPOUNDS
Disclosed are a variety of amphoteric compounds containing a quaternary nitrogen group, a covalently bound counterion, and an ester or amide group. These amphoteric compounds can be advantageously prepared via a chemoenzymatic green process, and exhibit good surfactant properties.
AMPHOTERIC COMPOUNDS
Disclosed are a variety of amphoteric compounds containing a quaternary nitrogen group, a covalently bound counterion, and an ester or amide group. These amphoteric compounds can be advantageously prepared via a chemoenzymatic green process, and exhibit good surfactant properties.
PROCESS FOR CONVERTING DISULFIDES TO CONVERSION PRODUCTS AND PROCESS FOR PRODUCING CYSTEIC ACID
Embodiments of the present disclosure generally relate to processes for converting disulfides to conversion products and to processes for producing cysteic acid. In an embodiment, a process for converting cystine to a conversion product is provided. The process include introducing an organic peroxide and water to cystine to form a mixture. The process further includes reacting the mixture, under conversion conditions, to form the conversion product, wherein the conversion product comprises cysteic acid, an amount of cysteic acid in the conversion product is greater than about 90 wt % based on a total weight of the conversion product, and the conversion conditions comprise a conversion temperature from about 15° C. to about 50° C. The process further includes heating the conversion product to remove the organic peroxide.
PROCESS FOR CONVERTING DISULFIDES TO CONVERSION PRODUCTS AND PROCESS FOR PRODUCING CYSTEIC ACID
Embodiments of the present disclosure generally relate to processes for converting disulfides to conversion products and to processes for producing cysteic acid. In an embodiment, a process for converting cystine to a conversion product is provided. The process include introducing an organic peroxide and water to cystine to form a mixture. The process further includes reacting the mixture, under conversion conditions, to form the conversion product, wherein the conversion product comprises cysteic acid, an amount of cysteic acid in the conversion product is greater than about 90 wt % based on a total weight of the conversion product, and the conversion conditions comprise a conversion temperature from about 15° C. to about 50° C. The process further includes heating the conversion product to remove the organic peroxide.
Photoresist composition, compound, and production method thereof
A photoresist composition containing (A) a polymer having a structural unit (I) that includes an acid-labile group, and (I) a compound represented by the following formula (1). In the following formula (1), R.sup.1, R.sup.2, R.sup.3 and R represent a hydrogen atom or a monovalent organic group having 1 to 20 carbon atoms. X represents a single bond, an oxygen atom or —NR.sup.a—. R.sup.a represents a hydrogen atom, a hydroxy group or a monovalent organic group having 1 to 20 carbon atoms, and optionally taken together represents a ring structure by binding with R each other. A.sup.− represents —SO.sub.3.sup.− or —CO.sub.2.sup.−. M.sup.+ represents a monovalent onium cation. ##STR00001##
Photoresist composition, compound, and production method thereof
A photoresist composition containing (A) a polymer having a structural unit (I) that includes an acid-labile group, and (I) a compound represented by the following formula (1). In the following formula (1), R.sup.1, R.sup.2, R.sup.3 and R represent a hydrogen atom or a monovalent organic group having 1 to 20 carbon atoms. X represents a single bond, an oxygen atom or —NR.sup.a—. R.sup.a represents a hydrogen atom, a hydroxy group or a monovalent organic group having 1 to 20 carbon atoms, and optionally taken together represents a ring structure by binding with R each other. A.sup.− represents —SO.sub.3.sup.− or —CO.sub.2.sup.−. M.sup.+ represents a monovalent onium cation. ##STR00001##