The present disclosure provides compounds and methods for inhibiting or degrading the N-terminal domain of the androgen receptor, as well as methods for treating cancers such as prostate cancer.

The present disclosure provides compounds and methods for inhibiting or degrading the N-terminal domain of the androgen receptor, as well as methods for treating cancers such as prostate cancer.

The present disclosure provides compounds and methods for inhibiting or degrading the N-terminal domain of the androgen receptor, as well as methods for treating cancers such as prostate cancer.

Novel biaromatic compounds, which are vitamin D analogs, processes for their preparation and cosmetic, dermatological and pharmaceutical preparations containing one or more of these compounds.

Compounds of formula I ##STR00001##
a process for preparation of compounds of formula I; precursor compounds of formula II ##STR00002##
a process for preparation of precursor compounds of formula II; compounds of formula III ##STR00003##
a process for the preparation of compounds of formula IV from compounds of formula III ##STR00004##
and the use of compounds of formula I for the preparation of compounds of formula IV.

Compounds of formula I ##STR00001##
a process for preparation of compounds of formula I; precursor compounds of formula II ##STR00002##
a process for preparation of precursor compounds of formula II; compounds of formula III ##STR00003##
a process for the preparation of compounds of formula IV from compounds of formula III ##STR00004##
and the use of compounds of formula I for the preparation of compounds of formula IV.

The present disclosure provides compounds and methods for inhibiting or degrading the N-terminal domain of the androgen receptor, as well as methods for treating cancers such as prostate cancer.

Object A problem to be solved by the present invention is to provide a luminescent nanocrystal complex that tends to disperse orderly in a polymer matrix and is superior in dispersibility in structurally mesogenic crosslinkable polymer matrices. Solution The present invention is a luminescent nanocrystal complex that contains luminescent nanocrystals and a surface-modifying compound that modifies the surface of the luminescent nanocrystals. The surface-modifying compound has a mesogenic backbone and a group that binds to the surface of the luminescent nanocrystals.

Compounds of formula I

##STR00001##

a process for preparation of compounds of formula I; precursor compounds of formula II

##STR00002##

a process for preparation of precursor compounds of formula II; compounds of formula III

##STR00003##

a process for the preparation of compounds of formula IV from compounds of formula III

##STR00004##

and the use of compounds of formula I for the preparation of compounds of formula IV.

Compounds of formula I

##STR00001##

a process for preparation of compounds of formula I; precursor compounds of formula II

##STR00002##

a process for preparation of precursor compounds of formula II; compounds of formula III

##STR00003##

a process for the preparation of compounds of formula IV from compounds of formula III

##STR00004##

and the use of compounds of formula I for the preparation of compounds of formula IV.