The disclosure provides processes for synthesizing compounds for use as CFTR modulators. ##STR00001##

The disclosure provides processes for synthesizing compounds for use as CFTR modulators. ##STR00001##

In order to provide a novel compound that has good solvent solubility, has high storage stability (dissolution stability) during refrigerated or frozen storage, and can be used as a crosslinking agent, a substituted trisphenol compound represented by formula (2) below is provided:

##STR00001##

In order to provide a novel compound that has good solvent solubility, has high storage stability (dissolution stability) during refrigerated or frozen storage, and can be used as a crosslinking agent, a substituted trisphenol compound represented by formula (2) below is provided:

##STR00001##

The present invention relates to an isomerization process of product obtained from bisphenol preparation from a condensation reaction of ketone and phenol comprising contacting the product obtained from bisphenol preparation from a condensation reaction of ketone and phenol with the ion exchange resin in aqueous condition for the isomerization of the undesired product and separating the product having higher bisphenol content, wherein said ion exchange resin is aromatic polymer having the sulfonic acid group modified with at least one promoter selected from the compound shown in the structure (I):

##STR00001##

The present invention relates to an isomerization process of product obtained from bisphenol preparation from a condensation reaction of ketone and phenol comprising contacting the product obtained from bisphenol preparation from a condensation reaction of ketone and phenol with the ion exchange resin in aqueous condition for the isomerization of the undesired product and separating the product having higher bisphenol content, wherein said ion exchange resin is aromatic polymer having the sulfonic acid group modified with at least one promoter selected from the compound shown in the structure (I):

##STR00001##

The invention relates to a composition that contains a binary mixture of bisphenol F and propoxylated bisphenol F. The aim of the invention is to provide aromatic polyols for preparing polyurethane-based and polyisocyanurate-based polymers, which ensure good handling from a technical point of view and good miscibility with the isocyanate component and render the end product flameproof. For this purpose, the invention devises a composition, which contains a binary mixture of ethoxylated bisphenol F and propoxylated bisphenol F in a weight ratio of 20:80 to 80:20.

The invention relates to a composition that contains a binary mixture of bisphenol F and propoxylated bisphenol F. The aim of the invention is to provide aromatic polyols for preparing polyurethane-based and polyisocyanurate-based polymers, which ensure good handling from a technical point of view and good miscibility with the isocyanate component and render the end product flameproof. For this purpose, the invention devises a composition, which contains a binary mixture of ethoxylated bisphenol F and propoxylated bisphenol F in a weight ratio of 20:80 to 80:20.

Provided is a thermally stable bisphenol composition whose increase in the Hazen color number is suppressed even under higher temperature conditions. A bisphenol composition including an aryl alkyl sulfide or a dialkyl disulfide at 0.1 ppb by mass to 1% by mass with respect to a bisphenol. A bisphenol composition including an aryl alkyl sulfide or a dialkyl disulfide at a predetermined ratio is thermally stable in terms of the Hazen color number, and shows no coloring problem under high temperature conditions. By using such a bisphenol composition, a polycarbonate resin having an excellent color tone can be produced.

Provided is a thermally stable bisphenol composition whose increase in the Hazen color number is suppressed even under higher temperature conditions. A bisphenol composition including an aryl alkyl sulfide or a dialkyl disulfide at 0.1 ppb by mass to 1% by mass with respect to a bisphenol. A bisphenol composition including an aryl alkyl sulfide or a dialkyl disulfide at a predetermined ratio is thermally stable in terms of the Hazen color number, and shows no coloring problem under high temperature conditions. By using such a bisphenol composition, a polycarbonate resin having an excellent color tone can be produced.