An integrated, co-product capable process is provided for producing taurine in particular with optionally one or both of monoethanolamine and diethanolamine from one or more sugars, comprising pyrolyzing one or more sugars to produce a crude pyrolysis product mixture including glycolaldehyde and formaldehyde; optionally removing formaldehyde from the crude pyrolysis product mixture, then combining the crude pyrolysis product mixture with an aminating agent in the presence of hydrogen and further in the presence of a catalyst to produce at least monoethanolamine from the crude pyrolysis product mixture; optionally recovering diethanolamine from the crude reductive amination product, sulfating at least a portion to all of the monoethanolamine product to produce 2-aminoethyl hydrogen sulfate ester; and sulfonating the 2-aminoethyl hydrogen sulfate ester to produce taurine.

An integrated, co-product capable process is provided for producing taurine in particular with optionally one or both of monoethanolamine and diethanolamine from one or more sugars, comprising pyrolyzing one or more sugars to produce a crude pyrolysis product mixture including glycolaldehyde and formaldehyde; optionally removing formaldehyde from the crude pyrolysis product mixture, then combining the crude pyrolysis product mixture with an aminating agent in the presence of hydrogen and further in the presence of a catalyst to produce at least monoethanolamine from the crude pyrolysis product mixture; optionally recovering diethanolamine from the crude reductive amination product, sulfating at least a portion to all of the monoethanolamine product to produce 2-aminoethyl hydrogen sulfate ester; and sulfonating the 2-aminoethyl hydrogen sulfate ester to produce taurine.

The present invention reports the obtaining of carbonyl compounds and derivatives, through syntheses with high yield and purity, providing anti-humoral active principles with selective antiproliferative properties and anti-metastatic activity.

The present invention refers to the development of new polyfunctional push-pull butadienes and their O and C-prenylated, benzoylated and iodide derivatives, with high electronic conjugation in the lateral chain. These compounds exhibit high anti-tumor selectivity, causing cell death by apoptosis, also show anti-metastatic and non-mutagenic properties in the experimental studies performed.

The present invention reports the obtaining of carbonyl compounds and derivatives, through syntheses with high yield and purity, providing anti-humoral active principles with selective antiproliferative properties and anti-metastatic activity.

The present invention refers to the development of new polyfunctional push-pull butadienes and their O and C-prenylated, benzoylated and iodide derivatives, with high electronic conjugation in the lateral chain. These compounds exhibit high anti-tumor selectivity, causing cell death by apoptosis, also show anti-metastatic and non-mutagenic properties in the experimental studies performed.

Provided is a chiller and system that may be utilized in a supercritical fluid chromatography method, wherein a non-polar solvent may replace a portion or all of a polar solvent for the purpose of separating or extracting desired sample molecules from a combined sample/solvent stream. The system may reduce the amount of polar solvent necessary for chromatographic separation and/or extraction of desired samples. The system may incorporate a supercritical fluid chiller, a supercritical fluid pressure-equalizing vessel and a supercritical fluid cyclonic separator. The supercritical fluid chiller allows for efficient and consistent pumping of liquid-phase gases employing off-the-shelf HPLC pumps. The pressure equalizing vessel allows the use of off-the-shelf HPLC column cartridges. The system may further incorporate the use of one or more disposable cartridges containing silica gel or other suitable medium. The system may also utilize an open loop cooling circuit using fluids with a positive Joule-Thompson coefficient.

Provided is a chiller and system that may be utilized in a supercritical fluid chromatography method, wherein a non-polar solvent may replace a portion or all of a polar solvent for the purpose of separating or extracting desired sample molecules from a combined sample/solvent stream. The system may reduce the amount of polar solvent necessary for chromatographic separation and/or extraction of desired samples. The system may incorporate a supercritical fluid chiller, a supercritical fluid pressure-equalizing vessel and a supercritical fluid cyclonic separator. The supercritical fluid chiller allows for efficient and consistent pumping of liquid-phase gases employing off-the-shelf HPLC pumps. The pressure equalizing vessel allows the use of off-the-shelf HPLC column cartridges. The system may further incorporate the use of one or more disposable cartridges containing silica gel or other suitable medium. The system may also utilize an open loop cooling circuit using fluids with a positive Joule-Thompson coefficient.

The present invention relates to a method for extracting aromatic compounds from aqueous, alkaline compositions containing lignin, which have a pH value of at least pH 10, in particular of at least pH 11, especially of at least pH 12, characterized in that the aqueous, alkaline composition containing lignin is treated with active carbon, the active carbon separates from the aqueous, alkaline composition containing lignin and the active carbon then undergoes a desorption step in order to extract the aromatic compounds, wherein the desorption step comprises the treatment of the active carbon (i) by means of an organic solvent, which essentially consists of one or more aromatic hydrocarbons or a mixture of at least one aromatic hydrocarbon together with at least one C.sub.1-C.sub.4 alkanol, or (ii) by means of water vapor,
wherein an eluate is obtained which contains the aromatic compounds.

The present invention relates to a method for extracting aromatic compounds from aqueous, alkaline compositions containing lignin, which have a pH value of at least pH 10, in particular of at least pH 11, especially of at least pH 12, characterized in that the aqueous, alkaline composition containing lignin is treated with active carbon, the active carbon separates from the aqueous, alkaline composition containing lignin and the active carbon then undergoes a desorption step in order to extract the aromatic compounds, wherein the desorption step comprises the treatment of the active carbon (i) by means of an organic solvent, which essentially consists of one or more aromatic hydrocarbons or a mixture of at least one aromatic hydrocarbon together with at least one C.sub.1-C.sub.4 alkanol, or (ii) by means of water vapor,
wherein an eluate is obtained which contains the aromatic compounds.

The present invention relates to a method for extracting aromatic compounds from aqueous, alkaline compositions containing lignin, which have a pH value of at least pH 10, in particular of at least pH 11, especially of at least pH 12, characterized in that the aqueous, alkaline composition containing lignin is treated with active carbon, the active carbon separates from the aqueous, alkaline composition containing lignin and the active carbon then undergoes a desorption step in order to extract the aromatic compounds, wherein the desorption step comprises the treatment of the active carbon (i) by means of an organic solvent, which essentially consists of one or more aromatic hydrocarbons or a mixture of at least one aromatic hydrocarbon together with at least one C.sub.1-C.sub.4 alkanol, or (ii) by means of water vapor,
wherein an eluate is obtained which contains the aromatic compounds.

Provided herein are compositions of compounds of formula (I), methods of inhibiting a bacterial infection by contacting a cell with a composition comprising a compound of formula (I), and methods of isolating compounds of formula (I) from an extract of Streptomyces tempisquensis.