C07D237/06

1,4-disubstituted pyridazine analogs thereof and methods for treating SMN-deficiency-related conditions

The present invention provides a compound of formula I or a pharmaceutically acceptable salt thereof; ##STR00001##
a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

1,4-disubstituted pyridazine analogs thereof and methods for treating SMN-deficiency-related conditions

The present invention provides a compound of formula I or a pharmaceutically acceptable salt thereof; ##STR00001##
a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

1,4-DISUBSTITUTED PYRIDAZINE ANALOGS THERE OF AND METHODS FOR TREATING SMN-DEFICIENCY-RELATED CONDITIONS

The present invention provides a compound of formula I or a pharmaceutically acceptable salt thereof;

##STR00001##

a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

1,4-DISUBSTITUTED PYRIDAZINE ANALOGS THERE OF AND METHODS FOR TREATING SMN-DEFICIENCY-RELATED CONDITIONS

The present invention provides a compound of formula I or a pharmaceutically acceptable salt thereof;

##STR00001##

a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

1,4-DISUBSTITUTED PYRIDAZINE ANALOGS THERE OF AND METHODS FOR TREATING SMN-DEFICIENCY-RELATED CONDITIONS

The present invention provides a compound of formula I or a pharmaceutically acceptable salt thereof;

##STR00001##

a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

1,4-DISUBSTITUTED PYRIDAZINE ANALOGS THERE OF AND METHODS FOR TREATING SMN-DEFICIENCY-RELATED CONDITIONS

The present invention provides a compound of formula I or a pharmaceutically acceptable salt thereof;

##STR00001##

a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

1,4-disubstituted pyridazine analogs there of and methods for treating SMN-deficiency-related conditions

The present invention provides a compound of formula I or a pharmaceutically acceptable salt thereof; ##STR00001##
a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

1,4-disubstituted pyridazine analogs there of and methods for treating SMN-deficiency-related conditions

The present invention provides a compound of formula I or a pharmaceutically acceptable salt thereof; ##STR00001##
a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

1,4-DISUBSTITUTED PYRIDAZINE ANALOGS THERE OF AND METHODS FOR TREATING SMN-DEFICIENCY-RELATED CONDITIONS

The present invention provides a compound of formula I or a pharmaceutically acceptable salt thereof;

##STR00001##

a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

1,4-DISUBSTITUTED PYRIDAZINE ANALOGS THERE OF AND METHODS FOR TREATING SMN-DEFICIENCY-RELATED CONDITIONS

The present invention provides a compound of formula I or a pharmaceutically acceptable salt thereof;

##STR00001##

a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.