Patent classifications
C07D251/16
Divalent nucleobase compounds and uses therefor
Described herein are novel divalent nucleobases that each bind two nucleic acid strands, matched or mismatched when incorporated into a nucleic acid or nucleic acid analog backbone (a genetic recognition reagent, or genetic recognition reagent). In one embodiment, the genetic recognition reagent is a peptide nucleic acid (PNA) or gamma PNA (γPNA) oligomer. Uses of the divalent nucleobases and monomers and genetic recognition reagents containing the divalent nucleobases also are provided.
Divalent nucleobase compounds and uses therefor
Described herein are novel divalent nucleobases that each bind two nucleic acid strands, matched or mismatched when incorporated into a nucleic acid or nucleic acid analog backbone (a genetic recognition reagent, or genetic recognition reagent). In one embodiment, the genetic recognition reagent is a peptide nucleic acid (PNA) or gamma PNA (γPNA) oligomer. Uses of the divalent nucleobases and monomers and genetic recognition reagents containing the divalent nucleobases also are provided.
Organic compound, and organic light-emitting diode and organic light-emitting device having the compound
An organic compound having a naphtho fluoranthene core and a hetero aromatic group bonded to a specific position of the naphtho fluoranthene core, an organic light-emitting diode and an organic light-emitting device including the compound are disclosed. Since the organic compound has a narrow Stokes Shift between an absorption wavelength and an emission wavelength, the organic compound has a broad overlapped area between its absorption peak and an emission peak of a delayed fluorescent material, and therefore it can emit blue light with high color purity. It is possible to manufacture an organic light-emitting diode (OLED) and an organic light-emitting device that enhance luminous efficiency and color purity using the organic compound.
Organic compound, and organic light-emitting diode and organic light-emitting device having the compound
An organic compound having a naphtho fluoranthene core and a hetero aromatic group bonded to a specific position of the naphtho fluoranthene core, an organic light-emitting diode and an organic light-emitting device including the compound are disclosed. Since the organic compound has a narrow Stokes Shift between an absorption wavelength and an emission wavelength, the organic compound has a broad overlapped area between its absorption peak and an emission peak of a delayed fluorescent material, and therefore it can emit blue light with high color purity. It is possible to manufacture an organic light-emitting diode (OLED) and an organic light-emitting device that enhance luminous efficiency and color purity using the organic compound.
CARBOCYCLIC NUCLEOSIDE ANALOGUE
The present invention relates to novel hydrolytically stable carbon-cyclic 5-aza-2-deoxycytidine and carbocyclic 5-aza-cytidine compounds and pro-drugs thereof as hypomethylating agents.
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CARBOCYCLIC NUCLEOSIDE ANALOGUE
The present invention relates to novel hydrolytically stable carbon-cyclic 5-aza-2-deoxycytidine and carbocyclic 5-aza-cytidine compounds and pro-drugs thereof as hypomethylating agents.
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Light-emitting material, compound, and organic light-emitting element
A compound represented by the following general formula is excellent in light emission properties. R.sup.1 and R.sup.2 each independently represent a fluorinated alkyl group, D represents a substituent in which Hammett's σ.sub.p value is negative, and A represents a substituent in which Hammett's σ.sub.p value is positive. ##STR00001##
Antimicrobial compounds and methods of making and using the same
The present invention relates generally to the field of antimicrobial compounds and to methods of making and using them. These compounds are useful for treating, preventing, and reducing the risk of microbial infections in humans and animals.
Antimicrobial compounds and methods of making and using the same
The present invention relates generally to the field of antimicrobial compounds and to methods of making and using them. These compounds are useful for treating, preventing, and reducing the risk of microbial infections in humans and animals.
SUBSTITUTED CARBONUCLEOSIDE DERIVATIVES USEFUL AS ANTICANCER AGENTS
Compounds of the general formula):
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processes for the preparation of these compounds, compositions containing these compounds, and the uses of these compounds.