The present invention provides compounds of Formula (I) which can be used as CCR8 inhibitors, which can be used as treatment or prevention of cancer using CCR8 inhibitors targeted tumor specific T regulatory cells.

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The present disclosure relates generally to therapeutic agents that may be useful as modulators of Integrated Stress Response (ISR) pathway.

The present disclosure relates generally to therapeutic agents that may be useful as modulators of Integrated Stress Response (ISR) pathway.

A nitrogen-containing ring derivative regulator, a preparation method therefor and use thereof. In particular, the present invention relates to a compound as represented by general formula (I), a preparation method therefor, a pharmaceutical composition containing the compound, and use thereof as a G protein-coupled receptor regulator in the treatment or prevention of central nervous system diseases and/or mental diseases.

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Lactam compounds of Formula I and their use for the treatment of neurological and psychiatric disorders including schizophrenia, bipolar disorder, anxiety disorder and insomnia is disclosed. ##STR00001##

Lactam compounds of Formula I and their use for the treatment of neurological and psychiatric disorders including schizophrenia, bipolar disorder, anxiety disorder and insomnia is disclosed. ##STR00001##

The present disclosure relates to a composition having a structure that includes ##STR00001##
where R.sub.1 includes at least one of hydrogen, carbon, and/or fluorine, and includes a covalent bond. In some embodiments of the present disclosure, R.sub.1 may include at least one of hydrogen, fluorine, a carboxyl group, a hydroxyl group, an alkoxy group, and/or a hydrocarbon chain. In some embodiments of the present disclosure, the composition may be derived from at least one of ##STR00002##
In some embodiments of the present disclosure, at least a portion of the composition may be bioderived.

The present disclosure relates to a composition having a structure that includes ##STR00001##
where R.sub.1 includes at least one of hydrogen, carbon, and/or fluorine, and includes a covalent bond. In some embodiments of the present disclosure, R.sub.1 may include at least one of hydrogen, fluorine, a carboxyl group, a hydroxyl group, an alkoxy group, and/or a hydrocarbon chain. In some embodiments of the present disclosure, the composition may be derived from at least one of ##STR00002##
In some embodiments of the present disclosure, at least a portion of the composition may be bioderived.

A polymerizable liquid crystal compound represented by the following general formula (1): ##STR00001##
(the symbols in the general formula (1) are as described in the DESCRIPTION.)

A polymerizable liquid crystal compound represented by the following general formula (1): ##STR00001##
(the symbols in the general formula (1) are as described in the DESCRIPTION.)