Provided herein is a process for resolving the (S)- and (R)- enantiomers of a compound of Formula (I), wherein L, R.sup.1, and R.sup.2 are defined herein.

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Provided herein is a process for resolving the (S)- and (R)- enantiomers of a compound of Formula (I), wherein L, R.sup.1, and R.sup.2 are defined herein.

##STR00001##

The present invention relates to the technical field of organic chemical engineering, and in particular to a key intermediate for synthesizing prostaglandin compounds and a preparation method therefor. When applied to the synthesis of prostaglandin compounds, the process flow is simplified, the yield and product purity are improved, the production costs are reduced, and the industrial application is easy.

##STR00001##

The present invention relates to new benzo-N-hydroxy amide compounds of formula (I) and pharmaceutically acceptable salts, isomers and prodrugs thereof, which show a significant inhibitory activity on the proliferation of tumor cells and specifically of cancer stem cells. ##STR00001##