Provided is a method for producing a halogenated hydrocarbon magnesium compound, the method including bringing a halogenated hydrocarbon compound into contact with magnesium having a specific surface area of 1×10.sup.−5 to 2×10.sup.−4 m.sup.2/g. Also provided are methods for producing a tertiary alcohol compound and an organosilicon compound, wherein said production method is utilized.

Provided is a method for producing a halogenated hydrocarbon magnesium compound, the method including bringing a halogenated hydrocarbon compound into contact with magnesium having a specific surface area of 1×10.sup.−5 to 2×10.sup.−4 m.sup.2/g. Also provided are methods for producing a tertiary alcohol compound and an organosilicon compound, wherein said production method is utilized.

The present invention provides methods for performing supercritical fluid chromatography comprising loading a sample to be separated by supercritical fluid chromatography onto a stationary phase comprising a spherical, monodisperse, core-shell particulate material comprising a nonporous core and one or more layers of a porous shell material surrounding the core, wherein the particles are sized less than 2 microns; and performing supercritical fluid chromatography to separate the sample.

The present invention provides methods for performing supercritical fluid chromatography comprising loading a sample to be separated by supercritical fluid chromatography onto a stationary phase comprising a spherical, monodisperse, core-shell particulate material comprising a nonporous core and one or more layers of a porous shell material surrounding the core, wherein the particles are sized less than 2 microns; and performing supercritical fluid chromatography to separate the sample.

A method of preparing catalyst particles (the “preparation method”) is disclosed. The preparation method comprises combining a Ru(0) complex and a carrier fluid to form a mixture and heating the mixture at an elevated temperature to nucleate the Ru(0) complex and give the catalyst particles in the carrier fluid. The preparation method optionally comprises isolating the catalyst particles from the carrier fluid. A method of preparing an organosilicon compound via dehydrogenative silylation with the catalyst particles (the “synthesis method”) is also disclosed. The synthesis method comprises reacting (A) an organohydridochlorosilane compound and (B) an alkene compound in the presence of (C) a catalyst, thereby preparing the organosilicon compound. The catalyst (C) of the synthesis method comprises the catalyst particles prepared by the preparation method.

The present disclosure relates to biosensors, kits and methods for detecting and/or quantifying lysophosphatidic acid (LPA) in a liquid sample such as a serum sample from a subject. The present disclosure also relates to linker compounds that are useful, for example, in the biosensors, kits and methods of the present disclosure and to methods for preparing a biosensor for detecting and/or quantifying lysophosphatidic acid (LPA) in a liquid sample.

The present disclosure relates to biosensors, kits and methods for detecting and/or quantifying lysophosphatidic acid (LPA) in a liquid sample such as a serum sample from a subject. The present disclosure also relates to linker compounds that are useful, for example, in the biosensors, kits and methods of the present disclosure and to methods for preparing a biosensor for detecting and/or quantifying lysophosphatidic acid (LPA) in a liquid sample.

A component made of micromachinable material for a high quality factor resonator or escapement mechanism, with a core made of micromachinable material and/or coated with an oxide layer, and including, on this core or on this oxide layer an abrasion resistant layer including a contact surface cooperating with an opposing contact surface an which is a hydrophobic self-assembled monolayer of the alkylsilane and/or fluorinated or perfluorinated or polyperfluorinated type, with a low or zero sulphur content, and arranged to repel any wetting agent from the area of contact between the contact surface and the opposing contact surface.

A component made of micromachinable material for a high quality factor resonator or escapement mechanism, with a core made of micromachinable material and/or coated with an oxide layer, and including, on this core or on this oxide layer an abrasion resistant layer including a contact surface cooperating with an opposing contact surface an which is a hydrophobic self-assembled monolayer of the alkylsilane and/or fluorinated or perfluorinated or polyperfluorinated type, with a low or zero sulphur content, and arranged to repel any wetting agent from the area of contact between the contact surface and the opposing contact surface.

Boron, phosphorus, arsenic, antimony and other impurities are at least partially removed from a mixture containing at least one chlorosilane and/or organochlorosilane by a) contacting the liquid mixture with a carrier material functionalized with an amidoxime of the general structural formula (I),

##STR00001##

where CAR=carrier material and R.sup.1, R.sup.2 are independently of one another H, alkyl, alkenyl, aryl, alkylaryl; and b) optionally removing the functionalized carrier material.