Patent classifications
C07F9/74
ANTI-CANCER AGENT
An anti-cancer agent is provided comprising a tumour homing peptide having, or having been modified to present, two cysteine residues, with an arsenic atom between, such that the tumour homing peptide cyclises to give an arsenic-containing anti-cancer agent. This allows for selection of an appropriate tumour homing peptide for treatment of a given cancer whereby the subsequent agent provides for a more targeted delivery of arsenic to the tumour microenvironment.
DEUTERATED OXOPHENYLARSINE COMPOUND AND USE THEREOF
Disclosed are a deuterated oxophenylarsine, or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition containing a pharmaceutically acceptable carrier and the deuterated oxophenylarsine. The deuterated oxophenylarsine can be used for treating and preventing cancers and related diseases.
APPLICATIONS OF P14K INHIBITOR IN INTRACELLULAR PROTEIN MISFOLDING-RELATED DISEASES AND LYSOSOMAL STORAGE DISEASES
Provided are uses of a PI4KIII? specific inhibitor in preventing or treating intracellular protein misfolding-related diseases, also provided are uses of the PI4KIII? specific inhibitor in preventing or treating lysosomal storage diseases.
HALOGENATED PHENYLARSINE OXIDE COMPOUND AND APPLICATION THEREOF
A fluorinated phenylarsine oxide or a pharmaceutically acceptable salt thereof, relating to a pharmaceutical composition containing a pharmaceutically acceptable carrier and a fluorinated phenylarsine oxide. The fluorinated phenylarsine oxide can be used for treating and preventing cancer and related diseases.
HALOGENATED PHENYLARSINE OXIDE COMPOUND AND APPLICATION THEREOF
A fluorinated phenylarsine oxide or a pharmaceutically acceptable salt thereof, relating to a pharmaceutical composition containing a pharmaceutically acceptable carrier and a fluorinated phenylarsine oxide. The fluorinated phenylarsine oxide can be used for treating and preventing cancer and related diseases.
Triarylphosphine or triarylarsine compound, alpha-olefin polymerization catalyst using the compound, ternary copolymer, and production process of alpha-olefin-((meth)acrylic acid)-based copolymer
To provide an industrially useful -olefin((meth)acrylic acid)-based olefin copolymer having both a high molecular weight and a high comonomer content, a catalyst component capable of realizing a production of two different kinds of -olefin((meth)acrylic acid)-based olefin copolymers, and a production process using the catalyst. An -olefin((meth)acrylic acid)-based olefin copolymer is produced by using a metal complex complexed with a ligand represented by the following formula (Y is phosphorus or arsenic) for a catalyst composition. ##STR00001##
Triarylphosphine or triarylarsine compound, alpha-olefin polymerization catalyst using the compound, ternary copolymer, and production process of alpha-olefin-((meth)acrylic acid)-based copolymer
To provide an industrially useful -olefin((meth)acrylic acid)-based olefin copolymer having both a high molecular weight and a high comonomer content, a catalyst component capable of realizing a production of two different kinds of -olefin((meth)acrylic acid)-based olefin copolymers, and a production process using the catalyst. An -olefin((meth)acrylic acid)-based olefin copolymer is produced by using a metal complex complexed with a ligand represented by the following formula (Y is phosphorus or arsenic) for a catalyst composition. ##STR00001##
Arsenic complexes for potential diagnostic applications
The present invention provides radioactive arsenic complexes useful in diagnostic and therapeutic applications and methods for forming those arsenic complexes.