Patent classifications
C08G63/91
Methods of making foams exhibiting desired properties from aromatic polyester polyether polyols derived from polyethylene terephthalates and foams made therefrom
The disclosure relates to methods of making foams comprising aromatic polyester polyether polyol materials derived from the transesterification of polyethylene terephthalate with either glycerin or trimethylolpropane, wherein each of these triols, independently, has a degree of ethoxylation of from 1 to 9. Uses of the foams are further disclosed. The disclosure further relates to selection of blowing agents suitable to generate a selected end use case. Yet further, the disclosure relates to selection of end uses, properties, and environmental profiles of the foams generated according to the methods herein, and selecting formulation variables suitable to obtain the foams.
Polymeric dispersants containing one or two quaternary amine anchoring groups with improved chemical and thermal stability
The present invention relates to a dispersant having a tertiary or quaternary amine anchoring group and a solubilizing polymer selected from C.sub.8-50 fatty acid; a C.sub.8-50 ak(en)yl substituted succinic acid, anhydride or partial ester; a dimer or trimer fatty acid; and/or polymers from repeating units of polyesters, polyethers, polyacrylate, polyamides, polyurethanes or mixtures of said repeating units in a random or blocky copolymer. The dispersants are an improvement in that the alkylene connecting group between the tertiary or quaternized amine and the solubilizing polymer lacks abstractable hydrogen atoms at the geminal carbon atom from the nitrogen of the tertiary or quaternized amine over the prior art. The dispersants are useful as dispersants with improved thermal stability and low amounts yellow color after aging at elevated temperatures.
FLOW CELLS
An example of a kit includes a flow cell, a primer fluid, and a cleaving fluid. The flow cell includes at least one surface functionalized with a polymeric hydrogel including azide functional groups or amine functional groups. The primer fluid includes a plurality of alkyne-containing primers, each alkyne-containing primer having an amino cleavable group attaching a primer sequence of the alkyne-containing primer to an alkyne-containing moiety of the alkyne-containing primer. The cleaving fluid includes a substance that is reactive with the amino cleavable group.
FLOW CELLS
An example of a kit includes a flow cell, a primer fluid, and a cleaving fluid. The flow cell includes at least one surface functionalized with a polymeric hydrogel including azide functional groups or amine functional groups. The primer fluid includes a plurality of alkyne-containing primers, each alkyne-containing primer having an amino cleavable group attaching a primer sequence of the alkyne-containing primer to an alkyne-containing moiety of the alkyne-containing primer. The cleaving fluid includes a substance that is reactive with the amino cleavable group.
Methods and compositions for preparing particle boards
An amorphous polylactic acid polymer having a weight average molecular weight in the range of about 35,000 to 180,000 is described. The polylactic acid polymer composition can be hammer milled without cryogenics result in the form of particles wherein 90% of the particles have particle size of about 250 μm or less and the material has a glass transition temperature of between about 55° C. to about 58° C. and a relative viscosity of about 1.45 to about 1.95 centipoise. The polymer composition can be used to form an aqueous suspension. The material is ideally suited for use in preparing particleboard. A method is disclosed for preparing such polylactic acid polymers. The method involves obtaining an amorphous polylactic acid polymer having a weight average molecular weight of between about 115,000 to about 180,000. Treating the polylactic acid polymer to reduce the molecular weight to between about 35,000 to 45,000 such that it has a glass transition temperature of between about 55° C. and 58° C. and a relative viscosity of about 1.45 to about 1.95. Material can be formed into particles in a commercial hammer mill with bypass such that 90% of the initial mass results in the particles which can pass thru a sieve having a pore size of about 250 μm. During particle board formation the temperature of around 140-140 C being reached to optimally activate the adhesive; Bond strengths and throughput rates of resulting particle boards can be controlled thereafter, with variable combination of particle sizes, adhesive loading and initial moisture content.
MACROMOLECULAR TRANSITION METAL COMPLEXES FOR TREATMENT OF CANCERAND PROCESS FOR THEIR PREPARATION
The present invention relates to macromolecular transition metal complexes, characterized by having the general formula (I), to the process for their preparation, and to bidentate and monodentate macroligands. The invention also refers to pharmaceutical compositions and medicaments containing said macromolecular transition metal complexes, and to the use of said pharmaceutical compositions, medicaments and macromolecular transition metal complexes for cancer therapy and/or cancer prevention, as antitumor agent in solid tumors, liquid tumors and/or metastases and/or as radiosensitizer agents.
COSMETIC COMPOSITION COMPRISING A GRAFTED POLYHYDROXYALKANOATE COPOLYMER IN A FATTY MEDIUM
The present invention relates to a cosmetic composition comprising a) one or more polyhydroxyalkanoate (PH A) copolymers which contain, and preferably consist of, at least two different repeating polymer units chosen from the units (A) and (B) below, and also the optical or geometrical isomers thereof, the organic or mineral acid or base salts thereof, and the solvates thereof such as hydrates: -[-0-CH(R.sup.1)—CH.sub.2—C(0)-]- unit (A) -[-0-CH(R.sup.2)—CH.sub.2—C(0)-]- unit (B) in which polymer units (A) and (B): —R.sup.1 represents a hydrocarbon-based chain chosen from i) linear or branched (C.sub.5-C.sub.28)alkyl, ii) linear or branched (C.sub.6-C.sub.28)alkenyl, iii) linear or branched (C.sub.6-C.sub.28)alkynyl; preferably, the hydrocarbon-based group is linear; said hydrocarbon-based chain being optionally substituted and/or interrupted with atoms or groups as described in the description; —R.sup.2 represents a cyclic or non-cyclic, linear or branched, saturated or unsaturated hydrocarbon-based group, comprising from 3 to 30 carbon atoms; b) a fatty medium comprising one or more fatty substances which are preferably liquid at 25° C. and at atmospheric pressure; it being understood that (A) is different from (B).
POLY(AMINE-CO-ESTER) POLYMERS WITH MODIFIED END GROUPS AND ENHANCED PULMONARY DELIVERY
Poly(amine-co-ester) polymers, methods of forming active agent-load polyplexes and particles therefrom, and methods of using them for delivery of nucleic acid agents with optimal uptake have been developed. Examples demonstrate critical molecular weights in combination with exposed carboxylic and/or hydroxyl groups, and methods of making. Typically, the compositions are less toxic, more efficient at drug delivery, or a combination thereof compared to a control other transfection reagents. In some embodiments, the compositions are suitable for in vivo delivery, and can be administered systemically to a subject to treat a disease or condition. For poly(amine-co-ester) polymers with specific amine or hydroxyl group containing end-groups in admixture with PEGylated poly(amine-co-ester) polymers, in vivo delivery to the lung by inhalation has been shown.
POLY(AMINE-CO-ESTER) POLYMERS WITH MODIFIED END GROUPS AND ENHANCED PULMONARY DELIVERY
Poly(amine-co-ester) polymers, methods of forming active agent-load polyplexes and particles therefrom, and methods of using them for delivery of nucleic acid agents with optimal uptake have been developed. Examples demonstrate critical molecular weights in combination with exposed carboxylic and/or hydroxyl groups, and methods of making. Typically, the compositions are less toxic, more efficient at drug delivery, or a combination thereof compared to a control other transfection reagents. In some embodiments, the compositions are suitable for in vivo delivery, and can be administered systemically to a subject to treat a disease or condition. For poly(amine-co-ester) polymers with specific amine or hydroxyl group containing end-groups in admixture with PEGylated poly(amine-co-ester) polymers, in vivo delivery to the lung by inhalation has been shown.
ESTER COMPOUND AND RESIN COMPOSITION
Compounds containing, in one molecule thereof, a structure represented by formula (1), a structure represented by formula (2), and a structure represented by formula (3) (all the symbols are those described in the specification).
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are useful as epoxy resin curing agents.